Limiting inter-annual variation in total allowable catch strategies. An application to ICES roundfish stocks

This study evaluated through simulation management strategy that stabilise catch levels by setting bounds on the inter-annual variability in Total Allowable Catches (TACs). An integrated modelling approach was used, which modelled both the ‘real’ and observed systems and the interactions between all system components. The modelling framework therefore allowed evaluation of the robustness of candidate management strategies to both the intrinsic properties of the systems, and the ability to observe, monitor, assess and control them. Strategies were evaluated in terms of level of risk (measured as the probability of spawning stock biomass falling below the biomass limit reference level for the stock) and cumulative yield. The simulation approach used provides a powerful tool for the examination of the performance of candidate management strategies. It has shown that better management is not necessarily going to be achieved by improving the assessement, since even with a perfect assessment (where the simulated working group knew stock status perfectly) stocks may crash at fishing levels that standard stochastic projections would suggest were safe. Also explicitly modelling the assessment process can result in quite different outcomes than those predicted by the simple projection traditionally used by stock assessment working groups. This is because the simple projection assumes that the status of the stock in the current year is known without error and that the target fishing mortality can be achieved without error. However, in practice the assessment is based on last years data and the effect of any management measure on SSB is only manifest, following the implementation of the quota, at the end of the following year. The choice of target and fishing mortality levels and minimum stock levels results from ICES interpretation of the precautionary approach. This lead to the definition of fishing mortality and biomass reference points that are intended to prevent over-fishing and to trigger recovery plans when a stock is overfished respectively. Although, fishing mortality and biomass reference points were originally intended to be independent, a fishing mortality level implies a corresponding biomass level. In the case of saithe a fishing mortality of 0.40 (i.e. the FPA level) would drive the stock to Blim, suggesting that the choice of biomass and target reference points are not consistent for this stock

Limiting inter-annual variation in total allowable catch strategies. An application to ICES roundfish stocks

This study evaluated through simulation management strategy that stabilise catch levels by setting bounds on the inter-annual variability in Total Allowable Catches (TACs). An integrated modelling approach was used, which modelled both the ‘real’ and observed systems and the interactions between all system components. The modelling framework therefore allowed evaluation of the robustness of candidate management strategies to both the intrinsic properties of the systems, and the ability to observe, monitor, assess and control them. Strategies were evaluated in terms of level of risk (measured as the probability of spawning stock biomass falling below the biomass limit reference level for the stock) and cumulative yield. The simulation approach used provides a powerful tool for the examination of the performance of candidate management strategies. It has shown that better management is not necessarily going to be achieved by improving the assessement, since even with a perfect assessment (where the simulated working group knew stock status perfectly) stocks may crash at fishing levels that standard stochastic projections would suggest were safe. Also explicitly modelling the assessment process can result in quite different outcomes than those predicted by the simple projection traditionally used by stock assessment working groups. This is because the simple projection assumes that the status of the stock in the current year is known without error and that the target fishing mortality can be achieved without error. However, in practice the assessment is based on last years data and the effect of any management measure on SSB is only manifest, following the implementation of the quota, at the end of the following year. The choice of target and fishing mortality levels and minimum stock levels results from ICES interpretation of the precautionary approach. This lead to the definition of fishing mortality and biomass reference points that are intended to prevent over-fishing and to trigger recovery plans when a stock is overfished respectively. Although, fishing mortality and biomass reference points were originally intended to be independent, a fishing mortality level implies a corresponding biomass level. In the case of saithe a fishing mortality of 0.40 (i.e. the FPA level) would drive the stock to Blim, suggesting that the choice of biomass and target reference points are not consistent for this stock

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

Idiopathic congenital nystagmus (ICN) is characterised by involuntary, periodic, predominantly horizontal, oscillations of both eyes. We identified 22 mutations in FRMD7 in 26 families with X-linked idiopathic congenital nystagmus. Screening of 42 ICN singleton cases (28 male, 14 females) yielded three mutations (7%). We found restricted expression of FRMD7 in human embryonic brain and developing neural retina suggesting a specific role in the control of eye movement and gaze stability

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

The nature and significance of Marx's critique of classical political economy

The thesis is concerned with a series of methodological aspects of Karl Marx's economic writings, notably Capital. These methodological questions are explored by means of a critical review of Marx's relationship to the school of classical political economy in Britain. Here emphasis is placed on David Ricardo. The aim of the thesis is to demonstrate that it is impossible to understand fully the revolution wrought by Marx in the field of political economy without having fundamental regard for the philosophical foundation of Marx's Capital. It is argued that Hegel is above all the key figure here and that a proper consideration of the influence of his philosophy in shaping Marx's intellectual development is of paramount importance. After an initial survey in which it is held that these matters have received little adequate attention in the past, attention is directed towards the major elements of Marx's critique of classical economics. Stress is placed on the empiricism which underlay much of this political economy and the consequences which this philosophical stance involved. To develop the argument, Marx's notion of labour is examined in detail. A more general analysis of the concepts employed by Marx in his work follows, designed to demonstrate concretely the fundamental nature of Marx's critique of the work of his predecessors. The opening chapters of Capital are subjected to a close textual scrutiny in order to highlight the dialectical character of Marx's work. Finally the nature of the notion of fetishism is explored with a view to establishing its centrality for Marx as well as to explain its absence from the work of the classical economists

An improved method for estimating individual growth variability in fish, and the correlation between von Bertalanffy growth parameters

A new method for estimating individual variability in the von Bertalanffy growth parameters of fish species is presented. The method uses a nonlinear random effects model, which explicitly assumes that an individual's growth parameters represent samples from a multivariate population of growth parameters characteristic of a species or population. The method was applied to backcalculated length-at-age data from the tropical emperor, Lethrinus mahsena. Individual growth parameter variability estimates were compared with those derived using the current "standard" method, which characterizes the joint distribution of growth parameter estimates obtained by independently fitting a growth curve to each individual data set. Estimates of mean von Bertalanffy growth parameters from the two methods were similar. However, estimated growth parameter variances were much higher using the standard method. Using the random effects model, the estimated correlation between population mean values of L-infinity and K was -0.52 or -0.42, depending on the marginal distribution assumed for K. The latter estimate had a 95% posterior credibility interval of -0.62 to -0.17. These represent the first reliable estimate of this correlation and confirm the view that these parameters are negatively correlated in fish populations; however, the absolute correlation value is somewhat lower than has been assumed