774 research outputs found
Die Spacer Thickness Reproduction for Central Incisor Crown Fabrication with Combined Computer-aided Design and 3D Printing Technology: An in vitro Study
Statement of problem
The inability to control die spacer thickness has been reported. However, little information is available on the congruency between the computer-aided design parameters for die spacer thickness and the actual printout. Purpose
The purpose of this study was to evaluate the accuracy and precision of the die spacer thickness achieved by combining computer-aided design and 3-dimensional printing technology. Material and Methods
An ivorine maxillary central incisor was prepared for a ceramic crown. The prepared tooth was duplicated by using polyvinyl siloxane duplicating silicone, and 80 die-stone models were produced from Type IV dental stone. The dies were randomly divided into 5 groups with assigned die spacer thicknesses of 25 μm, 45 μm, 65 μm, 85 μm, and 105 μm (n=16). The printed resin copings, obtained from a printer (ProJet DP 3000; 3D Systems), were cemented onto their respective die-stone models with self-adhesive resin cement and stored at room temperature until sectioning into halves in a buccolingual direction. The internal gap was measured at 5 defined locations per side of the sectioned die. Images of the printed resin coping/die-stone model internal gap dimensions were obtained with an inverted bright field metallurgical microscope at ×100 magnification. The acquired digital image was calibrated, and measurements were made using image analysis software. Mixed models (α=.05) were used to evaluate accuracy. A false discovery rate at 5% was used to adjust for multiple testing. Coefficient of variation was used to determine the precision for each group and was evaluated statistically with the Wald test (α=.05). Results
The accuracy, expressed in terms of the mean differences between the prescribed die spacer thickness and the measured internal gap (standard deviation), was 50 μm (11) for the 25 μm group simulated die spacer thickness, 30 μm (10) for the 45 μm group, 15 μm (14) for the 65 μm group, 3 μm (23) for the 85 μm group, and -10 μm (32) for the 105 μm group. The precision mean of the measurements, expressed as a coefficient of variation, ranged between 14% and 33% for the 5 groups. Conclusions
For the accuracy evaluation, statistically significant differences were found for all the groups, except the group of 85 μm. For the precision assessment, the coefficient of variation was above 10% for all groups, showing the printer’s inability to reproduce the uniform internal gap within the same group
Spatial Morphometric Analysis Using Shape-Changing Rigid-Body Chains
Morphometry is the quantitative comparison of shapes, primarily curves. As an alternate to classical methods of spatial morphometry, this work investigates a kinematic synthesis methodology for designing a spatial chain of rigid-bodies to match arbitrary spatial curves. The goal is to find a single set of spatial bodies that can be moved to approximately align with any given set of spatial curves. Previous rigid-body shape-change morphometry work focused on mechanisms composed of rigid planar links connected by prismatic and revolute joints to approximate planar curves. Open space curves are the current focus of the research. The primary advantage of this method is its capacity to describe the difference in space curves with a limited number of parameters.https://ecommons.udayton.edu/stander_posters/2395/thumbnail.jp
Validation of Kepler's Multiple Planet Candidates. III: Light Curve Analysis & Announcement of Hundreds of New Multi-planet Systems
The Kepler mission has discovered over 2500 exoplanet candidates in the first
two years of spacecraft data, with approximately 40% of them in candidate
multi-planet systems. The high rate of multiplicity combined with the low rate
of identified false-positives indicates that the multiplanet systems contain
very few false-positive signals due to other systems not gravitationally bound
to the target star (Lissauer, J. J., et al., 2012, ApJ 750, 131). False
positives in the multi- planet systems are identified and removed, leaving
behind a residual population of candidate multi-planet transiting systems
expected to have a false-positive rate less than 1%. We present a sample of 340
planetary systems that contain 851 planets that are validated to substantially
better than the 99% confidence level; the vast majority of these have not been
previously verified as planets. We expect ~2 unidentified false-positives
making our sample of planet very reliable. We present fundamental planetary
properties of our sample based on a comprehensive analysis of Kepler light
curves and ground-based spectroscopy and high-resolution imaging. Since we do
not require spectroscopy or high-resolution imaging for validation, some of our
derived parameters for a planetary system may be systematically incorrect due
to dilution from light due to additional stars in the photometric aperture.
None the less, our result nearly doubles the number of verified exoplanets.Comment: 138 pages, 8 Figures, 5 Tables. Accepted for publications in the
Astrophysical Journa
The Detection and Characterization of cm Radio Continuum Emission from the Low-mass Protostar L1014-IRS
Observations by the Cores to Disk Legacy Team with the Spitzer Space
Telescope have identified a low luminosity, mid-infrared source within the
dense core, Lynds 1014, which was previously thought to harbor no internal
source. Followup near-infrared and submillimeter interferometric observations
have confirmed the protostellar nature of this source by detecting scattered
light from an outflow cavity and a weak molecular outflow. In this paper, we
report the detection of cm continuum emission with the VLA. The emission is
characterized by a quiescent, unresolved 90 uJy 6 cm source within 0.2" of the
Spitzer source. The spectral index of the quiescent component is between 6 cm and 3.6 cm. A factor of two increase in 6 cm
emission was detected during one epoch and circular polarization was marginally
detected at the level with Stokes {V/I} % . We have
searched for 22 GHz H2O maser emission toward L1014-IRS, but no masers were
detected during 7 epochs of observations between June 2004 and December 2006.
L1014-IRS appears to be a low-mass, accreting protostar which exhibits cm
emission from a thermal jet or a wind, with a variable non-thermal emission
component. The quiescent cm radio emission is noticeably above the correlation
of 3.6 cm and 6 cm luminosity versus bolometric luminosity, indicating more
radio emission than expected. We characterize the cm continuum emission in
terms of observations of other low-mass protostars, including updated
correlations of centimeter continuum emission with bolometric luminosity and
outflow force, and discuss the implications of recent larger distance estimates
on the physical attributes of the protostar and dense molecular core.Comment: 14 pages. Accepted for publication in Ap
MACSIMS : multiple alignment of complete sequences information management system
BACKGROUND: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as genomics, proteomics or transcriptomics. New information management systems are now needed for the collection, validation and analysis of the vast amount of heterogeneous data available. Multiple alignments of complete sequences provide an ideal environment for the integration of this information in the context of the protein family. RESULTS: MACSIMS is a multiple alignment-based information management program that combines the advantages of both knowledge-based and ab initio sequence analysis methods. Structural and functional information is retrieved automatically from the public databases. In the multiple alignment, homologous regions are identified and the retrieved data is evaluated and propagated from known to unknown sequences with these reliable regions. In a large-scale evaluation, the specificity of the propagated sequence features is estimated to be >99%, i.e. very few false positive predictions are made. MACSIMS is then used to characterise mutations in a test set of 100 proteins that are known to be involved in human genetic diseases. The number of sequence features associated with these proteins was increased by 60%, compared to the features available in the public databases. An XML format output file allows automatic parsing of the MACSIM results, while a graphical display using the JalView program allows manual analysis. CONCLUSION: MACSIMS is a new information management system that incorporates detailed analyses of protein families at the structural, functional and evolutionary levels. MACSIMS thus provides a unique environment that facilitates knowledge extraction and the presentation of the most pertinent information to the biologist. A web server and the source code are available at
Kepler-68: Three Planets, One With a Density Between That of Earth and Ice Giants
NASA's Kepler Mission has revealed two transiting planets orbiting Kepler-68.
Follow-up Doppler measurements have established the mass of the innermost
planet and revealed a third jovian-mass planet orbiting beyond the two
transiting planets. Kepler-68b, in a 5.4 day orbit has mass 8.3 +/- 2.3 Earth,
radius 2.31 +/- 0.07 Earth radii, and a density of 3.32 +/- 0.92 (cgs), giving
Kepler-68b a density intermediate between that of the ice giants and Earth.
Kepler-68c is Earth-sized with a radius of 0.953 Earth and transits on a 9.6
day orbit; validation of Kepler-68c posed unique challenges. Kepler-68d has an
orbital period of 580 +/- 15 days and minimum mass of Msin(i) = 0.947 Jupiter.
Power spectra of the Kepler photometry at 1-minute cadence exhibit a rich and
strong set of asteroseismic pulsation modes enabling detailed analysis of the
stellar interior. Spectroscopy of the star coupled with asteroseismic modeling
of the multiple pulsation modes yield precise measurements of stellar
properties, notably Teff = 5793 +/- 74 K, M = 1.079 +/- 0.051 Msun, R = 1.243
+/- 0.019 Rsun, and density 0.7903 +/- 0.0054 (cgs), all measured with
fractional uncertainties of only a few percent. Models of Kepler-68b suggest it
is likely composed of rock and water, or has a H and He envelope to yield its
density of about 3 (cgs).Comment: 32 pages, 13 figures, Accepted to Ap
Fundamental Properties of Kepler Planet-Candidate Host Stars using Asteroseismology
We have used asteroseismology to determine fundamental properties for 66
Kepler planet-candidate host stars, with typical uncertainties of 3% and 7% in
radius and mass, respectively. The results include new asteroseismic solutions
for four host stars with confirmed planets (Kepler-4, Kepler-14, Kepler-23 and
Kepler-25) and increase the total number of Kepler host stars with
asteroseismic solutions to 77. A comparison with stellar properties in the
planet-candidate catalog by Batalha et al. shows that radii for subgiants and
giants obtained from spectroscopic follow-up are systematically too low by up
to a factor of 1.5, while the properties for unevolved stars are in good
agreement. We furthermore apply asteroseismology to confirm that a large
majority of cool main-sequence hosts are indeed dwarfs and not misclassified
giants. Using the revised stellar properties, we recalculate the radii for 107
planet candidates in our sample, and comment on candidates for which the radii
change from a previously giant-planet/brown-dwarf/stellar regime to a
sub-Jupiter size, or vice versa. A comparison of stellar densities from
asteroseismology with densities derived from transit models in Batalha et al.
assuming circular orbits shows significant disagreement for more than half of
the sample due to systematics in the modeled impact parameters, or due to
planet candidates which may be in eccentric orbits. Finally, we investigate
tentative correlations between host-star masses and planet candidate radii,
orbital periods, and multiplicity, but caution that these results may be
influenced by the small sample size and detection biases.Comment: 19 pages, 10 figures, 4 tables; accepted for publication in ApJ;
machine-readable versions of tables 1-3 are available as ancillary files or
in the source code; v2: minor changes to match published versio
European adult smokers' perceptions of the harmfulness of e-cigarettes relative to combustible cigarettes: cohort findings from the 2016 and 2018 EUREST-PLUS ITC Europe Surveys
Background: This study presents perceptions of the harmfulness of electronic cigarettes (e-cigarettes) relative to combustible cigarettes among smokers from six European Union (EU) countries, prior to the implementation of the EU Tobacco Products Directive (TPD), and 2 years post-TPD. Methods: Data were drawn from the EUREST-PLUS ITC Europe Surveys, a cohort study of adult smokers (>= 18 years) from Germany, Greece, Hungary, Poland, Romania and Spain. Data were collected in 2016 (pre-TPD: N = 6011) and 2018 (post-TPD: N = 6027). Weighted generalized estimating equations were used to estimate perceptions of the harmfulness of e-cigarettes compared to combustible cigarettes (less harmful, equally harmful, more harmful or 'don't know'). Results: In 2016, among respondents who were aware of e-cigarettes (72.2%), 28.6% reported that they perceived e-cigarettes to be less harmful than cigarettes (range 22.0% in Spain to 34.1% in Hungary). In 2018, 72.2% of respondents were aware of e-cigarettes, of whom 28.4% reported perceiving that e-cigarettes are less harmful. The majority of respondents perceived e-cigarettes to be equally or more harmful than cigarettes in both 2016 (58.5%) and 2018 (61.8%, P>0.05). Overall, there were no significant changes in the perceptions that e-cigarettes are less, equally or more harmful than cigarettes, but 'don't know' responses significantly decreased from 12.9% to 9.8% (P = 0.036). The only significant change within countries was a decrease in 'don't know' responses in Spain (19.3-9.4%, P = .001). Conclusions: The majority of respondents in these six EU countries perceived e-cigarettes to be equally or more harmful than combustible cigarettes
Obliquities of Hot Jupiter host stars: Evidence for tidal interactions and primordial misalignments
We provide evidence that the obliquities of stars with close-in giant planets
were initially nearly random, and that the low obliquities that are often
observed are a consequence of star-planet tidal interactions. The evidence is
based on 14 new measurements of the Rossiter-McLaughlin effect (for the systems
HAT-P-6, HAT-P-7, HAT-P-16, HAT-P-24, HAT-P-32, HAT-P-34, WASP-12, WASP-16,
WASP-18, WASP-19, WASP-26, WASP-31, Gl 436, and Kepler-8), as well as a
critical review of previous observations. The low-obliquity (well-aligned)
systems are those for which the expected tidal timescale is short, and likewise
the high-obliquity (misaligned and retrograde) systems are those for which the
expected timescale is long. At face value, this finding indicates that the
origin of hot Jupiters involves dynamical interactions like planet-planet
interactions or the Kozai effect that tilt their orbits, rather than
inspiraling due to interaction with a protoplanetary disk. We discuss the
status of this hypothesis and the observations that are needed for a more
definitive conclusion.Comment: Accepted for publication in ApJ; typos corrected, 2 broken references
fixed, 26 pages, 25 figure
Transit Timing Observations from Kepler: III. Confirmation of 4 Multiple Planet Systems by a Fourier-Domain Study of Anti-correlated Transit Timing Variations
We present a method to confirm the planetary nature of objects in systems
with multiple transiting exoplanet candidates. This method involves a
Fourier-Domain analysis of the deviations in the transit times from a constant
period that result from dynamical interactions within the system. The
combination of observed anti-correlations in the transit times and mass
constraints from dynamical stability allow us to claim the discovery of four
planetary systems Kepler-25, Kepler-26, Kepler-27, and Kepler-28, containing
eight planets and one additional planet candidate.Comment: Accepted to MNRA
- …