140 research outputs found
A Good Worker is Hard to Find: The Determinants of Skills Shortages in New Zealand Firms
This paper investigates the determinants of firms’ external skill shortages – that is, vacancies that are hard to fill for skillĂ‚Ârelated reasons. This paper utilises a speciallyĂ‚Âdesigned survey, the Business Strategy and Skills (BSS) module of the Business Operations Survey 2008 (BOS 2008). We estimate the determinants of firms reporting having vacancies and skill shortage in comparison to the nonĂ‚ÂskillĂ‚Ârelated vacancies using probit models and twoĂ‚Âstage (Heckman) probit models with selection, to enable us to distinguish between those factors related with the firm posting a vacancy and those that make them difficult to fill. We consider a broad suite of variables, including firm’s size and industry, their market focus, R&D investment, innovation, previous performance (e.g. productivity), the degree of competition they are subject to
A Good Worker is Hard to Find: The Determinants of Skills Shortages in New Zealand Firms
This paper investigates the determinants of firms’ external skill shortages – that is, vacancies that are hard to fill for skillĂ‚Ârelated reasons. This paper utilises a speciallyĂ‚Âdesigned survey, the Business Strategy and Skills (BSS) module of the Business Operations Survey 2008 (BOS 2008). We estimate the determinants of firms reporting having vacancies and skill shortage in comparison to the nonĂ‚ÂskillĂ‚Ârelated vacancies using probit models and twoĂ‚Âstage (Heckman) probit models with selection, to enable us to distinguish between those factors related with the firm posting a vacancy and those that make them difficult to fill. We consider a broad suite of variables, including firm’s size and industry, their market focus, R&D investment, innovation, previous performance (e.g. productivity), the degree of competition they are subject to
The Training's A-Comin' In: An Analysis of Training Decision Using Microdata
In this paper we utilise a speciallyÂdesigned survey, the Business Strategy and Skills (BSS) module of the Business Operations Survey 2008 (BOS 2008) to investigate the determinants and intensity of training in three aspects: training of new staff; training of existing staff changing roles and the training of existing staff for their existing roles. We examine both the probability and intensity of each type of training as a function of the external and internal skill gaps as well as a suite of other variables including the firms' size, previous performance, its ownership, its competitive environment and the occupational breakdown of its staff
The Training's A-Comin' In: An Analysis of Training Decision Using Microdata
In this paper we utilise a speciallyĂ‚Âdesigned survey, the Business Strategy and Skills (BSS) module of the Business Operations Survey 2008 (BOS 2008) to investigate the determinants and intensity of training in three aspects: training of new staff; training of existing staff changing roles and the training of existing staff for their existing roles. We examine both the probability and intensity of each type of training as a function of the external and internal skill gaps as well as a suite of other variables including the firms’ size, previous performance, its ownership, its competitive environment and the occupational breakdown of its staff
Stone artefacts on the seabed at a submerged freshwater spring confirm a drowned cultural landscape in Murujuga, Western Australia
We report the discovery and identification of five ancient stone artefacts associated with a submerged freshwater spring at the underwater archaeological site WH1 in Murujuga (Dampier Archipelago), Western Australia. A limiting date applied to the site based on timing of inundation suggests it was occupied in the Late Pleistocene or Early Holocene. The site is situated well below the intertidal zone having been recorded at 14 m depth in Flying Foam Passage. This discovery highlights the high potential of these submerged springs as archaeological survey targets. We discuss results of a recent survey that expands the number of confirmed artefacts located at WH1 and the geomorphological context in a large calcareous depression associated with a freshwater source. This study demonstrates how submerged landscape research using a suite of technologies can reveal archaeological assemblages in this tropical geomorphological environment, and that adapted techniques could be applied to other tropical conditions such as mangrove coasts, large deltaic plains, or reef-building environments. There are likely thousands of drowned archaeological sites on the continental shelf of the tropics, extending from the intertidal zone to the lowest point of the culturally occupied landmass, at approximately 130 m below modern sea level
Recent Developments in the UNO MK 3 Process–A Low Cost, Environmentally Benign Precipitating Process for CO2 Capture
AbstractSubstantial progress in the development of the UNO MK 3 process and it's cost reduction capabilities has been made since previously reported [1]. In particular, the recent results of two pilot plant trials of the process continue to demonstrate and confirm the major features of the UNO MK 3 process:Low overall cost (up to 50% less than the best amines)Multi-impurity capture and production of valuable by-products (no degradation products)Low energy of regeneration (less than 2.5 GJ/T CO2)Low volatility and environmental impact (SOx and NOx converted to fertilizer products)A good fit with existing global potassium markets (no additional potassium required)These new results are groundbreaking in terms of advancing the process; with no major barriers evident for scaling up the process from the current pilot scale (TRL 5) to larger scale demonstration (TRL 6/7) over the next few years
Haematological cancers: improving outcomes. A summary of updated NICE service guidance in relation to Specialist Integrated Haematological Malignancy Diagnostic Services (SIHMDS).
Haematological malignancies are a diverse group of cancers that affect the blood, bone marrow and lymphatic systems. Laboratory diagnosis of haematological malignancies is dependent on combining several technologies, including morphology, immunophenotyping, cytogenetics and molecular genetics correlated clinical details and classification according to the current WHO guidelines. The concept of the Specialised Integrated Haematological Malignancy Diagnostic Services (SIHMDS) has evolved since the UK National Institute for Health and Care Excellence (NICE) Improving Outcomes Guidance (IOG) in 2003 and subsequently various models of delivery have been established. As part of the 2016 update to the NICE IOG, these models were systematically evaluated and recommendations produced to form the basis for quality standards for future development of SIHMDS. We provide a summary of the systematic review and recommendations. Although the recommendations pertain to the UK National Health Service (NHS), they have relevance to the modern delivery of diagnostic services internationally
Erratum to : Analysis of the mitochondrial maxicircle of Trypanosoma lewisi, a neglected human pathogen
BACKGROUND
The haemoflagellate Trypanosoma lewisi is a kinetoplastid parasite which, as it has been recently reported to cause human disease, deserves increased attention. Characteristic features of all kinetoplastid flagellates are a uniquely structured mitochondrial DNA or kinetoplast, comprised of a network of catenated DNA circles, and RNA editing of mitochondrial transcripts. The aim of this study was to describe the kinetoplast DNA of T. lewisi.
METHODS/RESULTS
In this study, purified kinetoplast DNA from T. lewisi was sequenced using high-throughput sequencing in combination with sequencing of PCR amplicons. This allowed the assembly of the T. lewisi kinetoplast maxicircle DNA, which is a homologue of the mitochondrial genome in other eukaryotes. The assembly of 23,745Â bp comprises the non-coding and coding regions. Comparative analysis of the maxicircle sequence of T. lewisi with Trypanosoma cruzi, Trypanosoma rangeli, Trypanosoma brucei and Leishmania tarentolae revealed that it shares 78Â %, 77Â %, 74Â % and 66Â % sequence identity with these parasites, respectively. The high GC content in at least 9 maxicircle genes of T. lewisi (ATPase6; NADH dehydrogenase subunits ND3, ND7, ND8 and ND9; G-rich regions GR3 and GR4; cytochrome oxidase subunit COIII and ribosomal protein RPS12) implies that their products may be extensively edited. A detailed analysis of the non-coding region revealed that it contains numerous repeat motifs and palindromes.
CONCLUSIONS
We have sequenced and comprehensively annotated the kinetoplast maxicircle of T. lewisi. Our analysis reveals that T. lewisi is closely related to T. cruzi and T. brucei, and may share similar RNA editing patterns with them rather than with L. tarentolae. These findings provide novel insight into the biological features of this emerging human pathogen
Perceptual and conceptual processing of visual objects across the adult lifespan
Abstract: Making sense of the external world is vital for multiple domains of cognition, and so it is crucial that object recognition is maintained across the lifespan. We investigated age differences in perceptual and conceptual processing of visual objects in a population-derived sample of 85 healthy adults (24–87 years old) by relating measures of object processing to cognition across the lifespan. Magnetoencephalography (MEG) was recorded during a picture naming task to provide a direct measure of neural activity, that is not confounded by age-related vascular changes. Multiple linear regression was used to estimate neural responsivity for each individual, namely the capacity to represent visual or semantic information relating to the pictures. We find that the capacity to represent semantic information is linked to higher naming accuracy, a measure of task-specific performance. In mature adults, the capacity to represent semantic information also correlated with higher levels of fluid intelligence, reflecting domain-general performance. In contrast, the latency of visual processing did not relate to measures of cognition. These results indicate that neural responsivity measures relate to naming accuracy and fluid intelligence. We propose that maintaining neural responsivity in older age confers benefits in task-related and domain-general cognitive processes, supporting the brain maintenance view of healthy cognitive ageing
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