Research on Green Design Strategy of Office Building

Green building design refers to reducing the energy consumption of buildings through the use of energy-saving and environmentally-friendly technologies during the design and construction of buildings. The consumption of water resources and electric energy in office buildings is significantly higher than that of ordinary residential buildings, which has a greater impact on the environment during the construction process. Therefore, the use of green building design in the design of office buildings plays an important role in reducing building energy consumption. This article takes an office building in Chongqing as an example to explain the green optimization design and provide support for subsequent related constructions

A Triad of Lys12, Lys41, Arg78 Spatial Domain, a Novel Identified Heparin Binding Site on Tat Protein, Facilitates Tat-Driven Cell Adhesion

Tat protein, released by HIV-infected cells, has a battery of important biological effects leading to distinct AIDS-associated pathologies. Cell surface heparan sulfate protoglycans (HSPGs) have been accepted as endogenous Tat receptors, and the Tat basic domain has been identified as the heparin binding site. However, findings that deletion or substitution of the basic domain inhibits but does not completely eliminate Tat–heparin interactions suggest that the basic domain is not the sole Tat heparin binding site. In the current study, an approach integrating computational modeling, mutagenesis, biophysical and cell-based assays was used to elucidate a novel, high affinity heparin-binding site: a Lys12, Lys41, Arg78 (KKR) spatial domain. This domain was also found to facilitate Tat-driven β1 integrin activation, producing subsequent SLK cell adhesion in an HSPG-dependent manner, but was not involved in Tat internalization. The identification of this new heparin binding site may foster further insight into the nature of Tat-heparin interactions and subsequent biological functions, facilitating the rational design of new therapeutics against Tat-mediated pathological events

Directivity Analysis of Piezoelectric Micromachined Ultrasonic Transducer Array

A piezoelectric micromachined ultrasonic transducer (pMUT) is proposed. The (Pt/Ti)/Polyimide/PZT/Si3N4/SiO2/Si/SiO2/Si3N4 multimorph structure is designed and fabricated with micromachined process, resonance frequency of which is supposed to locate near 53.6 kHz. To improve the directivity pattern and increase radiation acoustic power, transducer array is adopted. A numerical simulation model was presented to study the influences of design parameters of plane combination array transducer. Interspacing between elements and number of elements are optimized. Subsequently, to verify the optimization results, experiment platform is established, directivity pattern of transducer array is obtained and compared with simulation results, which validated the optimization. The results provide the basis for structural design and fabrication of pMUT, a reliable reference for optimization of transducer array, and a method to test the directivity pattern

Research on Green Design Strategy of Office Building

Green building design refers to reducing the energy consumption of buildings through the use of energy-saving and environmentally-friendly technologies during the design and construction of buildings. The consumption of water resources and electric energy in office buildings is significantly higher than that of ordinary residential buildings, which has a greater impact on the environment during the construction process. Therefore, the use of green building design in the design of office buildings plays an important role in reducing building energy consumption. This article takes an office building in Chongqing as an example to explain the green optimization design and provide support for subsequent related constructions

Patients’ Preference for Physician Attire in the Internal Medicine Outpatient Department

Objective. To investigate patients’ preference and the attitude towards physician attire in an internal medicine clinic in China. Methods. This study was conducted from 1 January 2021 to 30 June 2021 in a tertiary care hospital in China. We surveyed 126 patients in the hospital with 6 sets of pictures of commonly worn physician attires in the hospital setting with a two-part questionnaire. The first part listed respondent demographics to collect basic information. The second part of the questionnaire was administered to adult patients who received care in the internal medicine clinics (outpatients). Survey forms collected demographic data (age, gender, patient age, education, marital status, and employment status), asked questions regarding 6 specific attires (scrubs, scrubs and white coat, casual, casual and white coat, business suit, and formal and white coat), and behavioral items (professional, responsible, reliable, knowledgeable, succession rate, and medical safety), finally, to assess the preference of attire on overall perception. Results. Scrubs and white coat scored the highest through 6 domains about physicians’ attire (professional, reliable, responsible, knowledgeable, medical safety, and succession rate, p<0.05 for all comparisons). A casual suit without a white coat was the least preferred across the surveyed attributes. There was a significant preference gap between wearing a white coat and not wearing a white coat (p<0.001). Physician attire to white coat was considered as more professional, reliable, responsible, knowledgeable, having greater medical safety, and a higher success rate than attires without white coat. Conclusion. Patients felt that the physician wearing a white coat was better than other attires. Scrubs and white coat was the most popular attire. Hospital or related authorities may promote the standardized wearing of white coats, leading in a greater patient-physician relationship