Scrotal calcinosis due to resorption of cyst walls: a case report

<p>Abstract</p> <p>Introduction</p> <p>Scrotal calcinosis is a rare benign entity defined as the presence of multiple calcified nodules within the scrotal skin. There are controversies about the origin of this entity. In fact, it is still debatable whether scrotal calcinosis is an idiopathic growth or dystrophic calcification of dartoic muscles. It is also unclear whether scrotal calcinosis originates from inflammation of epidermal cysts affected by mild to moderate inflammation of mononuclear cells, from foreign body granuloma formation followed by resorption of cyst walls or from eccrine epithelial cysts.</p> <p>Case presentation</p> <p>We report a 41-year-old male Turkish patient presenting with a 10-year history of scrotal tumours increasing slowly in size and number. Histopathologically, there was no epithelial lining around the calcified nodules, but there was fibrosis adjacent to atrophic stratified squamous epithelium.</p> <p>Conclusion</p> <p>Results of histopathological examinations suggested that scrotal calcinosis might have been due to resorption of cyst walls. Surgery remains the key for this problem. In cases of non-massive scrotal calcinosis, like the case presented here, excision of the nodules from the affected part of the scrotal wall and repairing the defect with horizontal stitches offer good cosmetic results without relapse.</p

Effect of sex in systemic psoriasis therapy: Differences in prescription, effectiveness and safety in the BIOBADADERM prospective cohort

The effect of sex on systemic therapy for psoriasis has not been well studied. The aim of this study was to analyse a large multicentre Spanish cohort of 2,881 patients with psoriasis (58.3% males), followed from January 2008 to November 2018, to determine whether sex influences prescription, effectiveness of therapy, and the risk of adverse events. The results show that women are more likely than men to be pre-scribed biologics. There were no differences between men and women in effectiveness of therapy, measur-ed in terms of drug survival. Women were more likely to develop adverse events, but the difference in risk was small and does not justify different management. Study limitations include residual confounding and the use of drug survival as a proxy for effectiveness.The BIOBADADERM project is promoted by the Fundación Piel Sana Academia Española de Dermatología y Venereología, which receives financial support from the Spanish Medicines and Health Products Agency (Agencia Española de Medicamentos y Productos Sanitarios) and from pharmaceutical companies (Abbott/Abbvie, Pfizer, MSD, Novartis, Lilly, Janssen and Almirall)

Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus

The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous. Pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus are rarer forms that present some clinical, histological and immunopathological characteristics that are different from the classical types. These are reviewed in this article. Future research may help definitively to locate the position of these forms in the pemphigus group, especially with regard to pemphigus herpetiformis and the IgG/ IgA pemphigus.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Dermatology DepartmentUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Dermatology and Pathology DepartmentsUNIFESP, EPM, Dermatology DepartmentUNIFESP, EPM, Dermatology and Pathology DepartmentsSciEL

Dinámica poblacional de Diaphorina citri (Hemiptera: Liviidae) en naranja, mandarina y limón y exploración de controladores biológicos en el Valle del Yeguare, Honduras

31 p.El Huanglongbing (HLB), enfermedad causada por Candidatus Liberibacter asiaticus, es considerada la amenaza más grande para la industria citrícola y es transmitida por Diaphorina citri Kuwayama (Hemiptera: Liviidae), un insecto reportado por primera vez en Honduras en 1989. El Huanglongbing fue detectado en Honduras en el 2009 en el departamento de Colón y desde entonces la producción de cítricos ha decrecido en un 40%. Hasta ahora no existe ninguna investigación respecto al comportamiento del vector en el país. Los objetivos de este estudio fueron determinar la fluctuación poblacional de D. citri, su abundancia en naranja, mandarina y limón y la exploración de controladores biológicos. Se realizaron muestreos quincenales usando trampas amarillas durante un año (julio de 2017 a julio de 2018) en un lote de cítricos de 6 ha en Zamorano, Valle de Yeguare, Honduras. Los resultados mostraron dos picos poblacionales de adultos, uno en noviembre de 2017 con 64 insectos y otro en junio de 2018 con 82 insectos, antecedidos por las épocas de mayor precipitación. De igual manera, se colectaron insectos en menor proporción en mayo y julio de 2018, 29 y 19 adultos respectivamente. De los cultivos estudiados, la mayor abundancia de D. citri se observó en naranja (79%), seguido de limón (13%) y, por último, mandarina (8%). Se identificaron las familias Coccinellidae, Reduviidae, Chrysopidae, Dolichopodidae, Aphelinidae, Encyrtidae, y Eulophidae como controladores biológicos de D. citri en la plantación de cítricos en Zamorano