189 research outputs found
Absorption in Ultra-Peripheral Nucleus-Atom Collisions in Crystal
The Glauber theory description of particle- and nucleus-crystal Coulomb
interactions at high-energy is developed. The allowance for the lattice thermal
vibrations is shown to produce strong absorption effect which is of prime
importance for quantitative understanding of the coherent Coulomb excitation of
ultra-relativistic particles and nuclei passing through the crystal.Comment: 8 pages, LaTe
Test of Lorentz Symmetry by using a 3He/129Xe Co-Magnetometer
To test Lorentz symmetry we used a 3He/129Xe co-magnetometer. We will give a
short summary of our experimental setup and the results of our latest
measurements. We obtained preliminary results for the equatorial component of
the background field interacting with the spin of the bound neutron: b_n < 3.72
x 10^(-32) GeV (95 C.L.).Comment: Presented at the Fifth Meeting on CPT and Lorentz Symmetry,
Bloomington, Indiana, June 28 - July 2, 201
Limit on Lorentz and CPT violation of the bound Neutron Using a Free Precession 3He/129Xe co-magnetometer
We report on the search for Lorentz violating sidereal variations of the
frequency difference of co-located spin-species while the Earth and hence the
laboratory reference frame rotates with respect to a relic background field.
The co-magnetometer used is based on the detection of freely precessing nuclear
spins from polarized 3He and 129Xe gas samples using SQUIDs as low-noise
magnetic flux detectors. As result we can determine the limit for the
equatorial component of the background field interacting with the spin of the
bound neutron to be bn < 3.7 x 10^{-32} GeV (95 C.L.).Comment: 5 pages, 4 figure
Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam
There is increasing evidence that mental health concerns, stress-related mental illnesses, and parental stress prior to conception have long-term effects on offspring outcomes. However, more work is needed to understand how pre-gestational stress might affect neurobehavioral outcomes in the mother. We investigated how chronic stress prior to gestation affects maternal behavior and related physiology, and aimed to determine the role that perinatal SSRIs have in altering these stress effects. To do this, female Sprague-Dawley rats were subject to chronic unpredictable stress (CUS) prior to breeding. During the perinatal period they were administered fluoxetine (10 mg/kg/day). Four groups of dams were studied: Control + Vehicle, Pre-gestational Stress + Vehicle, Control + Fluoxetine and Pre-gestational Stress + Fluoxetine. Maternal weight, breeding success, and maternal caregiving behaviors were recorded. Measures of serum corticosterone and corticosteroid-binging globulin (CBG) and the number of immature neurons in the dorsal hippocampus were also assessed in the late postpartum. Main findings show pre-gestational stress resulted in poor reproductive success and maintenance of pregnancy. Pre-gestationally stressed dams also showed higher levels of nursing and fewer bouts of licking/grooming offspring in the first week postpartum – behaviors that were not reversed by perinatal fluoxetine treatment. In the dam, perinatal fluoxetine treatment reversed the effect of pre-gestational maternal stress on serum corticosterone levels and increased serum CBG levels as well as neurogenesis in the dorsal hippocampus. Maternal corticosterone levels significantly correlated with blanket and passive nursing. This work provides evidence for a long-term impact of stress prior to gestation in the mother, and shows that perinatal SSRI medications can prevent some of these effects. © 2017 Elsevier B.V
Ultra-sensitive magnetometry based on free precession of nuclear spins
We discuss the design and performance of a very sensitive low-field
magnetometer based on the detection of free spin precession of gaseous, nuclear
polarized 3He or 129Xe samples with a SQUID as magnetic flux detector. The
device will be employed to control fluctuating magnetic fields and gradients in
a new experiment searching for a permanent electric dipole moment of the
neutron as well as in a new type of 3He/129Xe clock comparison experiment which
should be sensitive to a sidereal variation of the relative spin precession
frequency. Characteristic spin precession times T_2 of up to 60h could be
measured. In combination with a signal-to-noise ratio of > 5000:1, this leads
to a sensitivity level of deltaB= 1fT after an integration time of 220s and to
deltaB= 10^(-4)fT after one day. Even in that sensitivity range, the
magnetometer performance is statistically limited, and noise sources inherent
to the magnetometer are not limiting. The reason is that free precessing 3He
(129Xe) nuclear spins are almost completely decoupled from the environment.
That makes this type of magnetometer in particular attractive for precision
field measurements where a long-term stability is required
Dosimetric precision of an ion beam tracking system
<p>Abstract</p> <p>Background</p> <p>Scanned ion beam therapy of intra-fractionally moving tumors requires motion mitigation. GSI proposed beam tracking and performed several experimental studies to analyse the dosimetric precision of the system for scanned carbon beams.</p> <p>Methods</p> <p>A beam tracking system has been developed and integrated in the scanned carbon ion beam therapy unit at GSI. The system adapts pencil beam positions and beam energy according to target motion.</p> <p>Motion compensation performance of the beam tracking system was assessed by measurements with radiographic films, a range telescope, a 3D array of 24 ionization chambers, and cell samples for biological dosimetry. Measurements were performed for stationary detectors and moving detectors using the beam tracking system.</p> <p>Results</p> <p>All detector systems showed comparable data for a moving setup when using beam tracking and the corresponding stationary setup. Within the target volume the mean relative differences of ionization chamber measurements were 0.3% (1.5% standard deviation, 3.7% maximum). Film responses demonstrated preserved lateral dose gradients. Measurements with the range telescope showed agreement of Bragg peak depth under motion induced range variations. Cell survival experiments showed a mean relative difference of -5% (-3%) between measurements and calculations within the target volume for beam tracking (stationary) measurements.</p> <p>Conclusions</p> <p>The beam tracking system has been successfully integrated. Full functionality has been validated dosimetrically in experiments with several detector types including biological cell systems.</p
Standardising Clinical Caremaps: Model, Method and Graphical Notation for Caremap Specification
Standardising care can improve patient safety and outcomes, and reduce the cost of providing healthcare services. Caremaps were developed to standardise care, but contemporary caremaps are not standardised. Confusion persists in terms of terminology, structure, content and development process. Unlike existing methods in the literature, the approach, model and notation presented in this chapter pays special attention to incorporation of clinical decision points as first-class citizens within the modelling process. The resulting caremap with decision points is evaluated through creation of a caremap for women with gestational diabetes mellitus. The proposed method was found to be an effective way for comprehensively specifying all features of caremaps in a standardised way that can be easily understood by clinicians. This chapter contributes a new standardised method, model and notation for caremap content, structure and development
Sex bias in biopsy samples collected from free-ranging dolphins
Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in European Journal of Wildlife Research 56 (2010): 151-158, doi:10.1007/s10344-009-0299-7.Biological samples of free-ranging dolphins are increasingly used to gain information on
population structure and ecology. In small cetaceans, the gender of individuals usually cannot
be determined at sea, and population sex ratio has to be inferred indirectly. We used
molecular sexing to determine the gender of 340 biopsy samples of bottlenose dolphins,
Tursiops truncatus, spotted dolphins, Stenella frontalis, and common dolphins, Delphinus
delphis, collected around the Azores and Madeira. Sex ratio was globally skewed in favor of
males, and differed between species and archipelagos. Skew was probably influenced by the
selectivity of biopsy collectors and seasonal or year-round predominance of males in natural
populations. Skew was also influenced by sampling duration and intensity. In the Azores,
when several samples were successively collected within the same group, the proportion of
female samples decreased as a function of sample order. This trend indicated a tendency for
females to increasingly avoid the boat while samples were being collected. It showed that
males and females reacted differently to the perturbation caused by the biopsy sampling
process (i.e. sample collection and driving style).Portuguese Foundation for
Science and Technology (FCT) and the FEDER program for funding the CETAMARH
(POCTI/BSE/38991/01) and the GOLFINICHO (POCI/BIA-BDE/61009/2004) projects,
S.Q.'s post-doctoral grants (IMAR/FCT- PDOC-006/2001-MoleGen and
SFRH/BPD/19680/2004), M.A.S.'s doctoral (SFRH/BD/8609/2002) and post-doctoral
(SFRH/BPD/29841/2006) grants, S.M.'s investigation assistant grant
(CETAMARHII/POCTI/BSE/38991/2001) and I.C.'s investigation assistant grants
(IMAR/FCT/GOLFINICHO/001/2005 and IMAR/FCT/GOLFINICHO/004/2006). FCT for its pluri-annual funding to Research Unit #531 and the EU funded
program Interreg IIIb for funding the MACETUS project (MAC/4.2/M10) as well as R.P. and S.M.’s grants (IMAR/INTERREGIIIb/MACETUS/MAC1/2)
Structural study of GaSb/AlSb strained-layer superlattice
Owing to the lattice mismatch between GaSb and AlSb, a superlattice consisting of alternating layers of these materials will be strained. We have carried out ion-channeling measurements by backscattering of 1.76-MeV He ions, and present an experimental procedure and a data-analysis technique to measure the difference in strain between the two individual layers of the superlattice. The data analysis is based on computer simulations of channeling, the accuracy of which is supported by the many fine details of the experiments reproduced in the simulations. X-ray rocking-curve analysis yielded detailed profiles of strains in directions perpendicular and parallel to the surface. The x-ray value for the strain present at an unirradiated spot on the crystal is in excellent agreement with the value calculated by elasticity theory. In the bombarded region, the values of strain are less than the value calculated by elasticity theory. It appears that bombardment by the He ions reduced the strain by 50% and created lateral inhomogeneities in the crystal structure
Spinal infection: state of the art and management algorithm
Spinal infection is a rare pathology although a concerning rising incidence has been observed in recent years. This increase might reflect a progressively more susceptible population but also the availability of increased diagnostic accuracy. Yet, even with improved diagnosis tools and procedures, the delay in diagnosis remains an important issue. This review aims to highlight the importance of a methodological attitude towards accurate and prompt diagnosis using an algorithm to aid on spinal infection management.
METHODS:
Appropriate literature on spinal infection was selected using databases from the US National Library of Medicine and the National Institutes of Health.
RESULTS:
Literature reveals that histopathological analysis of infected tissues is a paramount for diagnosis and must be performed routinely. Antibiotic therapy is transversal to both conservative and surgical approaches and must be initiated after etiological diagnosis. Indications for surgical treatment include neurological deficits or sepsis, spine instability and/or deformity, presence of epidural abscess and upon failure of conservative treatment.
CONCLUSIONS:
A methodological assessment could lead to diagnosis effectiveness of spinal infection. Towards this, we present a management algorithm based on literature findings
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