Solid State Air Purification System

Life support systems in spacecraft are designed to provide a safe, habitable environment for the astronauts, and one of the most significant challenges is managing acceptable air quality. Carbon dioxide (CO2) is respired normally by humans at concentrations that are toxic if inhaled directly, and as a result cabin air must be tightly managed. The Carbon Dioxide Removal Assembly (CDRA) currently on board the ISS is the best functioning technology for manned space cabins, but has two significant drawbacks:1. The CDRA requires that air be dried prior to CO2 capture, and this costs energy _ in fact, the system spends 4X more energy drying the air than in actually capturing and releasing carbon dioxide. 2. The CDRA works in batch mode, while downstream CO2 processing systems require a continuous stream of CO2. This adds unnecessary complexity, as well as a second parasitic energy loss.An ideal system would process CO2 continuously without any need for drying of the air, and without any moving parts. Such a system would require a fraction of the size and weight of the CDRA while dropping the cost of CO2 capture by 5X or more. Such a technology would be enabling for future long term manned flight missions, such as a mission to Mars. eSionic is developing a new electrochemical membrane technology using its patented innovations in electrolyte materials. In Phase I of this program eSionic has demonstrated continuous gas separation using only electricity to drive the separation, with no moving parts or pressure drops. In Phase II, eSionic will demonstrate long-term operation of the membranes consistent with the needs of NASA for this development program

Listening to Children and Young People’s (CYP) Experience and Perceptions During the Period of COVID-19 and Their Advice for Teachers and Schools

This research project aimed to elicit the views of children and young people (CYP) about their experience of COVID-19, and their advice to teachers and schools. The views of fourteen CYP aged between 9 and 15 years of age from within and around London were ascertained through individual semi-structured interviews and analysed through thematic analysis. There were a variety of responses from CYP, including the following: a deep appreciation for their teachers and their support throughout the pandemic; stories of positive personal growth and spending more time with their family. However, their inability to see friends and the challenges of learning from home had a considerable impact on some CYP who would have liked home learning to have been more personalised, interactive and varied and for there to have been a greater awareness of workload. A list of issues for consideration and a checklist based upon the CYP’s views have been compiled, for the use of schools and teachers. Given the small sample, the timing of the study and the fact that the pandemic is ongoing, some suggestions for further research are indicated

Sensory Nerve Innervation of Epineurial Arterioles of the Sciatic Nerve Containing Calcitonin Gene–Related Peptide: Effect of Streptozotocin-Induced Diabetes

The authors have determined that epineurial arterioles of the sciatic nerve are innervated by nonadrenergic, noncholinergic nerves that contribute to the regulation of vasodilation. Using immunohistochemistry, the authors determined that nerves innervating epineurial arterioles contain the neuropeptide calcitonin gene–related peptide (CGRP). Using streptozotocin-induced diabetic rats, the authors demonstrated that CGRP content in sensory nerves innervating epineurial arterioles and vasodilation in response to exogenous CGRP was decreased. In summary, epineurial arterioles of the sciatic nerve are innervated by sensory nerves containing the neuropeptide CGRP. The diabetes-like condition induced by streptozotocin reduces the content of CGRP in these nerves and exogenous CGRPmediated vasodilation. CGRP is likely an important regulator of vascular tone and compromising its function could contribute to nerve ischemia and diabetic neuropathy

Dual pathologic findings on heat-denatured Tc-99m erythrocyte scintigraphy with computed tomographic correlation

A 70-year-old man with a 3-year history of chronic lymphocytic leukemia and resistant immune thrombocytopenia underwent splenectomy after an episode of life-threatening gastrointestinal bleeding. Recurrent thrombocytopenia, abdominal pain, and further gastrointestinal blood loss ensued. Radiologic (via computed tomographic scan [CT]) and colonoscopic assessment confirmed metastatic colon carcinoma. The ongoing blood loss was caused by severe thrombocytopenia. A heat-denatured Tc-99m erythrocyte study was performed. Results of that study not only confirmed the presence of residual or regenerated splenic tissue but also revealed several defects in hepatic uptake. These corresponded to the CT scan findings and were consistent with the known hepatic metastases