17 research outputs found
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Analysis of Ferroelectric Ceramic Fabricated by Binder Jetting Technology
The M-Lab system from ExOne was used to fabricate 3D structures of BaTiO3 ceramic
with applications that include dielectric capacitors, sensors, and integrated circuits. For this
project, layer thicknesses of 15 and 30 μm and various percentages of binder saturation were
used to fabricate components from powder. An organic binding agent was utilized during the
printing process and later burned out at ~600°C prior to sintering. Multiple building parameters
and sintering profiles were analyzed and compared in an attempt to obtain dense parts while
examining shrinkage percentage variations.Mechanical Engineerin
Next Generation Orthopaedic Implants by Additive Manufacturing Using Electron Beam Melting
This paper presents some examples of knee and hip implant components containing porous structures and fabricated in monolithic forms utilizing electron beam melting (EBM). In addition, utilizing stiffness or relative stiffness versus relative density design plots for open-cellular structures (mesh and foam components) of Ti-6Al-4V and Co-29Cr-6Mo alloy fabricated by EBM, it is demonstrated that stiffness-compatible implants can be fabricated for optimal stress shielding for bone regimes as well as bone cell ingrowth. Implications for the fabrication of patient-specific, monolithic, multifunctional orthopaedic implants using EBM are described along with microstructures and mechanical properties characteristic of both Ti-6Al-4V and Co-29Cr-6Mo alloy prototypes, including both solid and open-cellular prototypes manufactured by additive manufacturing (AM) using EBM
Fabrication of Metal and Alloy Components by Additive Manufacturing: Examples of 3D Materials Science
ObjectiveThis paper provides a brief review of relatively new additive manufacturing technologies for the fabrication of unusual and complex metal and alloy products by laser and electron beam melting. A number of process features and product microstructures are illustrated utilizing 3D optical and transmission electron microscope image compositions representing examples of 3D materials science.MethodsProcessing methods involving electron beam melting (EBM) and a process referred to as direct metal laser sintering (DMLS), often called selective laser melting (SLM) are described along with the use of light (optical) microscopy (OM), transmission electron microscopy (TEM), and X-ray diffraction (XRD) to elucidate microstructural phenomena.ResultsExamples of EBM and SLM studies are presented in 3D image compositions. These include EBM of Ti-6Al-4V, Cu, Co-base superalloy and Inconel 625; and SLM of 17-4 PH stainless steel, Inconel 718 and Inconel 625.Conclusions3D image compositions constituting 3D materials science provide effective visualization for directional solidification-related phenomena associated with the EBM and SLM fabrication of a range of metals and alloys, especially microstructures and microstructural architectures
Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study
Interactions between macrophages and adipocytes are early molecular factors influencing adipose tissue (AT) dysfunction, resulting in high leptin, low adiponectin circulating levels and low-grade metaflammation, leading to insulin resistance (IR) with increased cardiovascular risk. We report the characterization of AT dysfunction through measurements of the adiponectin/leptin ratio (ALR), the adipo-insulin resistance index (Adipo-IRi), fasting/postprandial (F/P) immunometabolic phenotyping and direct F/P differential gene expression in AT biopsies obtained from symptom-free adults from the GEMM family study. AT dysfunction was evaluated through associations of the ALR with F/P insulin-glucose axis, lipid-lipoprotein metabolism, and inflammatory markers. A relevant pattern of negative associations between decreased ALR and markers of systemic low-grade metaflammation, HOMA, and postprandial cardiovascular risk hyperinsulinemic, triglyceride and GLP-1 curves was found. We also analysed their plasma non-coding microRNAs and shotgun lipidomics profiles finding trends that may reflect a pattern of adipose tissue dysfunction in the fed and fasted state. Direct gene differential expression data showed initial patterns of AT molecular signatures of key immunometabolic genes involved in AT expansion, angiogenic remodelling and immune cell migration. These data reinforce the central, early role of AT dysfunction at the molecular and systemic level in the pathogenesis of IR and immunometabolic disorders
Additive Layer Manufacturing Of TI-6AL-4V By Electron Beam Melting From Powder Particles: Solid, Mesh And Foam Components Study
Additive Manufacturing by Electron Beam Melting Rapid Manufacturing is a technology that consists of the fabrication of a CAD design by melting powder particles in a layer by layer fashion. In this study, Ti-6Al-4V has been utilized to fabricate solid, mesh and foam components by EBM technologies. Powder analysis of Ti-6Al-4V was performed to obtain a better understanding of the porosity obtained by the system. After proper optimization of the machine, and porosity control, microstructural analysis was performed to the components already mentioned and correlated by transmission electron microscopy. Besides the microstructural analysis, tensile and hardness testing was performed to the components. Variations in density, and/or wall thickness of the components result in a variance in cooling rates that provide differences in microstructure and hardness discussed in this thesis. As a result, and mainly due to the astonishing properties obtained by these components a wide variety of fields can be benefited from these technologies
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Installation and Thermal Feedback from a Multi-wavelength Pyrometer in Electron Beam Melting
The purpose of this paper is to outline and discuss the installation and use of a multi-wavelength
pyrometer for process temperature monitoring in Electron Beam Melting (EBM). A multi-wavelength
pyrometer was externally mounted atop an EBM system to observe and record surface temperatures
during the fabrication process. The multi-wavelength pyrometer is a non-contact device capable of
measuring the temperature of an object without the need of knowing the object’s emissivity. Temperature
data from the EBM system thermocouple and the multi-wavelength pyrometer were compared, and it was
determined that the pyrometer measurements were reasonable. During fabrication, the multi-wavelength
pyrometer allowed the characterization of the EBM process that consisted of various steps during
fabrication (e.g. heating of the build platform, powder deposition, and melting). Measurement of surface
temperatures during fabrication can be useful for parameter development of novel materials, prediction of
resulting microstructural architectures, and ultimately as feedback used in a closed-loop control system,
allowing full spatial and temporal control of melting and microstructure.Mechanical Engineerin
Characterization and Cytotoxic Assessment of Ballistic Aerosol Particulates for Tungsten Alloy Penetrators into Steel Target Plates
The nature and constituents of ballistic aerosol created by kinetic energy penetrator rods of tungsten heavy alloys (W-Fe-Ni and W-Fe-Co) perforating steel target plates was characterized by scanning and transmission electron microscopy. These aerosol regimes, which can occur in closed, armored military vehicle penetration, are of concern for potential health effects, especially as a consequence of being inhaled. In a controlled volume containing 10 equispaced steel target plates, particulates were systematically collected onto special filters. Filter collections were examined by scanning and transmission electron microscopy (SEM and TEM) which included energy-dispersive (X-ray) spectrometry (EDS). Dark-field TEM identified a significant nanoparticle concentration while EDS in the SEM identified the propensity of mass fraction particulates to consist of Fe and FeO, representing target erosion and formation of an accumulating debris field. Direct exposure of human epithelial cells (A549), a model for lung tissue, to particulates (especially nanoparticulates) collected on individual filters demonstrated induction of rapid and global cell death to the extent that production of inflammatory cytokines was entirely inhibited. These observations along with comparisons of a wide range of other nanoparticulate species exhibiting cell death in A549 culture may suggest severe human toxicity potential for inhaled ballistic aerosol, but the complexity of the aerosol (particulate) mix has not yet allowed any particular chemical composition to be identified