Effects of fatty acids upon LDL catabolism in cultured cells

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Upaya Meningkatkan Hasil Belajar Matematika Materi Penjumlahan di Kelas V MI Muhammadiyah Sipedang Kecamatan Banjarmangu Kabupaten Banjarnegara dengan Menggunakan Metode The Power of Two

Skripsi ini dilatarbelakangi oleh pembelajaran matematika di Kelas V MI Muhammadiyah Sipedang Kecmatan Banjarmangu Kabupaten Banjar Negara dilakukan dengan menggunakan metode konvensional dengan ceramah, tanya jawab dan resitasi yang tentunya menjadikan siswa tidak mengalami pembelajarannya langsung dan mempersulit siswa dalam memahami materi matematika, Untuk itu, sebagai tenaga pendidik harus bisa mengurangi dan menghilangkan persepsi yang salah tersebut, dengan cara memilih metode pembelajaran yang lebih bervariasi dan tepat, Salah satu metode pembelajaran yang memenuhi kriteria adalah metode the power of two. Studi ini dimaksudkan untuk menjawab permasalahan: 1) bagaimana penerapan metode the power of two pada mata pelajaran matematika materi penjumlahan di kelas V MI Muhammadiyah Sipedang Kecmatan Banjarmangu Kabupaten Banjar negara? 2) apakah metode the power of two dapat meningkatkan hasil belajar matematika materi penjumlahan di kelas V MI Muhammadiyah Sipedang Kecmatan Banjarmangu Kabupaten Banjar negara? Permasalahan tersebut di bahas melalui penelitian tindakan kelas yang dilakukan melalui 2 siklus dengan setiap siklus tahapannya adalah perencanaan, tindakan, observasi dan refleksi. Hasil penelitian menunjukkan bahwa 1) Penerapan metode the power of two pada mata pelajaran matematika materi penjumlahan di kelas V MI Muhammadiyah Sipedang Kecamatan Banjarmangu Kabupaten Banjar negara dilakukan dengan melaksanakan pembelajaran yang memanfaatkan kekuatan dua siswa atau berpasangan untuk menyelesaikan masalah yang diberikan guru, selain itu pasangan tersebut juga mencoba menjawab pertanyaan dari pasangan lain sehingga terjadilah proses saling ketergantungan positif diantara pasangan. 2) Metode the power of two dapat mengurangi kesulitan belajar matematika materi penjumlahan di kelas V MI Muhammadiyah Sipedang Kecamatan Banjarmangu Kabupaten Banjar negara, hal ini terlihat dari hasil belajar yang di dapat siswa setelah melakukan tindakan dimana pada pra siklus ketuntasan ada 15 siswa atau 47%, pada siklus I ketuntasan ada 21 siswa atau 66% dan pada siklus II ketuntasan sudah mencapai 28 siswa atau 88%, begitu juga keaktifan belajar siswa juga mengalami kenaikan dimana pada siklus I ada 15 siswa atau 47 dan pada siklus II sudah mencapai 27 siswa atau 84

Should Any Workplace Be Exempt from Smoke-Free Law: The Irish Experience

Background. In 2004, the Irish Government introduced national legislation banning smoking in workplaces; with exemptions for “a place of residence”. This paper summarises three Irish studies of exempted premises; prisons, psychiatric hospitals and nursing homes. Methods. PM2.5 and nicotine were measured in nursing homes and psychiatric hospitals, in addition to ultrafine particles in the hospitals. In the prisons, officers (n = 30) completed exhaled breath Carbon Monoxide (CO) measurements. Questionnaires determined officers' opinion on introducing smoking prohibitions in prisons. Nursing home smoking policies were examined and questionnaires completed by staff regarding workplace secondhand smoke (SHS) exposure. Findings. Ultrafine particle concentrations in psychiatric hospitals averaged 130,000  cm3, approximately 45% higher than Dublin pub (35.5 μg/m3) pre ban. PM2.5 levels in psychiatric hospitals (39.5 μg/m3) were similar to Dublin pubs (35.5 μg/m3) pre ban. In nursing homes permitting smoking, similar PM2.5 levels (33 μg/m3) were measured, with nicotine levels (0.57 μg/m3) four times higher than “non-smoking” nursing homes (0.13 μg/m3). In prisons, 44% of non-smoking officers exhibited exhaled breath CO criteria for light to heavy smokers. Conclusions. With SHS exposure levels in some exempted workplaces similar to Dublin pubs levels pre ban, policies ensuring full protection must be developed and implemented as a right for workers, inmates and patients

Design of a new movement competence assessment for children aged 8–12: A Delphi poll study

Assessing children's movement competence (MC) offers numerous benefits for academics, practitioners, clinicians and children, allowing individuals to meet children's developmental needs and improve their MC. Yet, there is concern that currently available assessment tools only provide a single plane (fundamental movement skills) perspective of a child's MC. The aim of this study was to elicit the expert opinion of a mixture of academics and practitioners from a variety of fields (research, education, sport, physiotherapy, athletic therapy) to design a tool to measure both the fundamental and functional movement skills of children aged 8–12. A three-round Delphi poll with an international panel of 17 academics ( n = 8) and practitioners ( n = 9) was conducted. The consensus was that the assessment should assess (a) object manipulation, (b) locomotor, and (c) stability MC and the assessment layout should be dynamic, incorporating a hybrid model of stations and a circuit. Expert consensus was that most skills were to be performed using the dominant and non-dominant side, with object manipulation skills assessed using process and product criteria. The consensus was also that the assessment should have varied ‘layers’ of marking criteria to cater for varying assessor expertise and have a series of ‘add-on” elements to provide a more detailed evaluation should it be needed. These findings present the foundation and content validity of an assessment which takes a dualistic view of children's movement skills, that could be used across several environments (schools, sports clubs, clinical settings, etc.) and could be suitable for use with a large group of children

SAFETEL randomised controlled feasibility trial of a safety planning intervention with follow-up telephone contact to reduce suicidal behaviour: study protocol

Introduction: There are no evidence-based interventions that can be administered in hospital settings following a general hospital admission after a suicide attempt. Aim: To determine whether a safety planning intervention (SPI) with follow-up telephone support (SAFETEL) is feasible and acceptable to patients admitted to UK hospitals following a suicide attempt. Methods and Analysis: Three-phase development and feasibility study with embedded process evaluation. Phase I comprises tailoring an SPI with telephone follow-up originally designed for veterans in the USA, for use in the UK. Phase II involves piloting the intervention with patients (n=30) who have been hospitalised following a suicide attempt. Phase III is a feasibility randomised controlled trial of 120 patients who have been hospitalised following a suicide attempt with a 6-month follow-up. Phase III participants will be recruited from across four National Health Service hospitals in Scotland and randomised to receive either the SPI with telephone follow-up and treatment as usual (n=80) or treatment as usual only (n=40). The primary outcomes are feasibility outcomes and include the acceptability of the intervention to participants and intervention staff, the feasibility of delivery in this setting, recruitment, retention and intervention adherence as well as the feasibility of collecting the self-harm readmission to hospital outcome data. Statistical analyses will include description of recruitment rates, intervention adherence/use, response rates and estimates of the primary outcome event rates, and intervention effect size (Phase III). Thematic analyses will be conducted on interview and focus group data. Ethics and Dissemination: The East of Scotland Research Ethics Service (EoSRES) approved this study in March 2017 (GN17MH101 Ref: 17/ES/0036). The study results will be disseminated via peer-reviewed publication and conference presentations. A participant summary paper will also be disseminated to patients, service providers and policy makers alongside the main publication. Trial Registration Number: ISRCTN62181241

A Global Network of Science and Technology Advice in Foreign Ministries

This paper is a product of the International Dialogue on Science and Technology Advice in Foreign Ministries (Vienna Dialogue) in October 2016, involving more than twenty nations and several international organisations. The event was a key step to further develop the Foreign Minister Science and Technology Advisor Network (FMSTAN), growing from an initial group of five nations. The Vienna Dialogue was convened by the Fletcher School of Law and Diplomacy, Tufts University, and the International Institute for Applied Systems Analysis (IIASA) at the Vienna headquarters of IIASA, bringing together diplomats from foreign ministries to consider the value of evidence for informed decision-making by nations with regard to issues, impacts and resources within, across and beyond national boundaries. The evidence comes from the natural and social sciences with engineering and medicine as well as other areas of technology. By building common interests among nations, science is a tool of diplomacy, promoting cooperation and preventing conflict in our world. Science diplomacy was discussed as an international, interdisciplinary and inclusive process to help balance national interests and common interests in view of urgencies today and across generations in our globally-interconnected civilization

Engaging Multistakeholder Perspectives to Identify Patient-Centered Research Priorities Regarding Vaccine Uptake Among Adults With Autoimmune Conditions

Objective: The study objective was to prioritize topics for future patient-centered research to increase uptake of common vaccines, such as for pneumococcal pneumonia, influenza, herpes zoster, human papillomavirus, and severe acute respiratory syndrome coronavirus 2, among adults living with autoimmune conditions. Methods: A steering committee (SC) was formed that included clinicians, patients, patient advocates, and researchers associated with rheumatic diseases (psoriatic arthritis, rheumatoid arthritis, vasculitis), inflammatory bowel disease, and multiple sclerosis. Through a scoping review and discussions, SC members identified research topics regarding vaccine uptake and/or hesitancy for prioritization. A larger multistakeholder alliance that included patients and patient advocates, clinicians, researchers, policy makers, regulators, and vaccine manufacturers conducted a modified Delphi exercise online with three rating rounds and one ranking round. Frequency analysis and comparisons across stakeholder groups were conducted. A weighted ranking score was generated for each item in the ranking round for final prioritization. Results: Through the Delphi process, 33 research topics were identified, of which 13 topics were rated as critical by more than 70% of all stakeholders (n = 31). The two highest ranked critical topics per the full stakeholder group were “How well a vaccine works for adults with autoimmune conditions” and “How beliefs about vaccine safety affect vaccine uptake.”. Conclusion: A multistakeholder group identified key topics as critically important priorities for future research to decrease vaccine hesitancy and improve uptake of vaccines for adults with autoimmune conditions