Performance Evaluation of Optimized Predictive Model for Software Defined Network Traffic Management using Machine Learning

Communication channel is essential in any type of engagement for delivering and receiving data via the internet. To determine the most efficient and safe way through which network data may travel while minimizing the danger of network breaches or cyber-attacks. The objective is to build an optimized network traffic management predictive model that can predict the ideal path in real-time while accounting through the dynamic nature of software defined network traffic and the continuously changing danger of landscaping. To design a robust model of the data and scalable system that can suggest accurate suggestions of route to the network managers, a thorough grasp of network’s infrastructure, data analysis, and machine learning techniques are applied. Choosing the optimum path route data from the sdn based network traffic dataset, the model suggests an optimal path to avoid network communication traffic and congestion. Here nine Machine Learning algorithms are explored and analysed their performance by using the percentage split, resampling and cross validation which originally recorded as 92.76% and after training with cross validation it improved to 98.40% providing the best optimal path with minimum congestions. Building the optimized network traffic management model not only provide network security but also contribute to environmental sustainability. Their capacity to properly filter and manage network traffic helps to decrease energy usage by predicting the optimal routes for software defined network traffic

Quantification of rutin and quercetin by HPTLC/HPLC and in vitro immunomodulatory and anticancer activities of Capparis moonii fruits extracts

Background: The current research was undertaken on dried fruits of Capparis moonii to screen its potential for immunomodulatory and cancer indications with identification of phytoconstituents by chromatographic techniques.Methods: Methanolic (MECN), hydro-methanolic (HMECN) and aqueous extracts (AQCN) of Capparis moonii were subjected to high performance thin layer chromatography (HPTLC) and high-performance liquid chromatography (HPLC) after studying the total phenolic and flavonoid content by using rutin and gallic acid as standards respectively as well as undertaking powder characteristics and preliminary phytochemical screening. Immunomodulatory activities covered were hemagglutination antibody titre and delayed-type hypersensitivity reaction with the aid of sheep red blood cells (0.5×109) as antigens.  The extracts were studied for antioxidant potential. Anticancer prospects were focusing on in vitro cell lines screening (MCF 7 and HCT 15) by Sulforhodamine B assay method and potato disc assay.Results: The total phenolic and flavonoid content of MECM, HMECM and AQCM fruits extracts were found to be 0.20, 0.11 and 0.47 mg of gallic acid/g and 78.3, 18.8 and 64.4 mg of rutin/g respectively. Rutin and quercetin were confirmed by HPTLC and HPLC showing well resolved peaks. IC50 values in antioxidant studies were found to be significant with all the extracts. Significant immunomodulatory effect was noticed at 200mg/kg in both models (high antibody titre levels and decrease paw volume after 48 h). Unsatisfactory results were observed with selected cell lines and disc assay.Conclusions: Thus, selected fruits may probably have immunomodulatory potential due to presence of flavonols (rutin and quercetin)

Endoscopic removal of intrauterine contraceptive device embedded into detrusor muscle of urinary bladder: our experience of two cases

Migration of intrauterine contraceptive device (IUD) into urinary bladder is a rare event, presenting as irritative lower urinary tract symptoms; we present two cases of migrated IUD into urinary bladder and embedded inside the detrusor muscle of bladder. Both patients were assessed by ultrasonography and computed tomography. Both patients were successfully treated by endoscopic approach via per urethral route. One patient was having embedded vertical arm of IUD which was pulled using forceps and second patient was having embedded horizontal arm of IUD in detrusor muscle which was treated by taking mucosal incision with help of Collin’s knife followed by pulling IUD with help of forceps. There was no evidence of fistula or any other complication. We would like to conclude that endoscopic removal of IUD embedded into detrusor muscle is safe, feasible alternative to open surgery without any further risk of fistula formation

A FRAMEWORK FOR P2P NETWORKING OF SMART DEVICES USING WI-FI DIRECT

ABSTRAC

Analysis of atmospheric ammonia over South and East Asia based on the MOZART-4 model and its comparison with satellite and surface observations

Limited availability of atmospheric ammonia (NH3) observations limits our understanding of controls on its spatial and temporal variability and its interactions with the ecosystem. Here we used the Model for Ozone and Related chemical Tracers version 4 (MOZART-4) global chemistry transport model and the Hemispheric Transport of Air Pollution version 2 (HTAP-v2) emission inventory to simulate global NH3 distribution for the year 2010. We presented a first comparison of the model with monthly averaged satellite distributions and limited ground-based observations available across South Asia. The MOZART-4 simulations over South Asia and East Asia were evaluated with the NH3 retrievals obtained from the Infrared Atmospheric Sounding Interferometer (IASI) satellite and 69 ground-based monitoring stations for air quality across South Asia and 32 ground-based monitoring stations from the Nationwide Nitrogen Deposition Monitoring Network (NNDMN) of China. We identified the northern region of India (Indo-Gangetic Plain, IGP) as a hotspot for NH3 in Asia, both using the model and satellite observations. In general, a close agreement was found between yearly averaged NH3 total columns simulated by the model and IASI satellite measurements over the IGP, South Asia (r=0.81), and the North China Plain (NCP), East Asia (r=0.90). However, the MOZART-4-simulated NH3 column was substantially higher over South Asia than East Asia, as compared with the IASI retrievals, which show smaller differences. Model-simulated surface NH3 concentrations indicated smaller concentrations in all seasons than surface NH3 measured by the ground-based observations over South and East Asia, although uncertainties remain in the available surface NH3 measurements. Overall, the comparison of East Asia and South Asia using both MOZART-4 model and satellite observations showed smaller NH3 columns in East Asia compared with South Asia for comparable emissions, indicating rapid dissipation of NH3 due to secondary aerosol formation, which can be explained by larger emissions of acidic precursor gases in East Asia

Vascular Invasion of Papillary Thyroid Carcinoma into Neck Veins and Superior Vena Cava: A Case Report

Papillary thyroid cancer is the most common thyroid malignancy in women which spreads through lymphatic. Even though microscopic vascular invasion has been published in the recent past, direct venous extension is rare. This case report is about a rare presentation of a Fine Needle Aspiration Cytology (FNAC) proven papillary thyroid carcinoma in a 45-year-old female patient, who presented with a swelling in the neck. The Contrast Enhanced Computed Tomography (CECT) of the neck showed multiple nodular lesions of both lobes of thyroid extending to the retrosternal region and direct tumour thrombus extension to thyroid veins, External Jugular Vein (EJV), Superior Vena Cava (SVC) and subcutaneous veins of neck with lung metastases

A randomized controlled trial to compare efficacy of collagen granule-based dressing versus conventional dressing in the management of diabetic foot ulcers

Background and Objective: Diabetic foot ulcers are the most common reason for frequent hospitalization of diabetic patients. Management of ulcers by appropriate clinical practices such as thorough dressing and sterile wound creation to achieve improved mobility as well as completeness of healing are the significant goals of the clinicians. The current study aimed to compare the efficacy of collagen granule-based dressing over the conventional dressing in the management of diabetic foot ulcers. Materials and Methods: A randomized controlled trial was conducted from January 2013 to December 2013. A total of 60 patients having diabetic foot ulcers were studied. Routine investigations such as complete blood count, fasting blood sugar, culture and antibiotic sensitivity, and X-ray of the foot were performed. Patients were divided into two groups: group A (n = 30; treated with topical collagen granules dressing) and Group B (n = 30; treated with conventional dressing). Data were analyzed using Microsoft Excel Spreadsheet, categorical data were expressed as rates, ratios, and percentages, and the comparison was performed using Chi-square test and Fisher's exact test. Results: At the end of week 2, the mean wound area, after the dressing, was significantly less in Group A compared to Group B (P ≤ 0.001). The study also showed lower number of patients with slough/necrotic tissue in Group A than in Group B (P ≤ 0.001). At the end of week 4, no patient with wound discharge was observed in Group A compared to Group B (P = 0.005). Conclusion: The treatment of diabetic foot ulcers with collagen granule resulted in the reduction in wound area, slough/necrotic tissue, and wound discharge, leading to early wound healing compared to conventional dressing

Performance Evaluation of Optimized Predictive Model for Software Defined Network Traffic Management using Machine Learning

<p>Communication channel is essential in any type of engagement for delivering and receiving data via the internet. To determine the most efficient and safe way through which network data may travel while minimizing the danger of network breaches or cyber-attacks. The objective is to build an optimized network traffic management predictive model that can predict the ideal path in real-time while accounting through the dynamic nature of software defined network traffic and the continuously changing danger of landscaping. To design a robust model of the data and scalable system that can suggest accurate suggestions of route to the network managers, a thorough grasp of network's infrastructure, data analysis, and machine learning techniques are applied. Choosing the optimum path route data from the sdn based network traffic dataset, the model suggests an optimal path to avoid network communication traffic and congestion. Here nine Machine Learning algorithms are explored and analysed their performance by using the percentage split, resampling and cross validation which originally recorded as 92.76% and after training with cross validation it improved to 98.40% providing the best optimal path with minimum congestions. Building the optimized network traffic management model not only provide network security but also contribute to environmental sustainability. Their capacity to properly filter and manage network traffic helps to decrease energy usage by predicting the optimal routes for software defined network traffic.</p&gt

Spontaneous large renal pelvis hematoma in ureteropelvic junction obstruction presenting as an acute abdomen: Rare case report

Patients with ureteropelvic junction (UPJ) obstruction can present with flank pain or hematuria. We present 20-year-old male presenting with acute pain in lumbar and right fossa with tenderness and guarding, this case was clinically mimicking general surgical emergency. On computed tomography with urography and angiography, there was 15 cm × 11 cm × 10 cm size non-enhancing hyperdense lesion (average Hounsfield units - +64) in right renal pelvis suggestive of hematoma. Patient's diethylenetriaminepentaacetic acid diuretic renography was suggestive of right kidney glomerular function rate of 48.4 ml/min with the relative function of 43%, Peak to half peak was not achieved. The patient was managed by retrograde ureteropyelography and double J stenting. After 1 month, clot size decreased to 4 cm × 3 cm × 2 cm. The patient had undergone open reduction Anderson hynes dismembered pyeloplasty with the removal of pelvis clot after 6 weeks. We report the first case of UPJ obstruction presenting as an acute abdomen and spontaneous hematuria with large pelvis clot without rupture of the renal pelvis