1,434 research outputs found
A note on a third order curvature invariant in static spacetimes
We consider here the third order curvature invariant
in static spacetimes
for which is conformally flat. We evaluate
explicitly the invariant for the -dimensional Majumdar-Papapetrou multi
black-holes solution, confirming that does indeed vanish on the event
horizons of such black-holes. Our calculations show, however, that solely the
vanishing of is not sufficient to locate an event horizon in
non-spherically symmetric spacetimes. We discuss also some tidal effects
associated to the invariant .Comment: 5 pages, 3 figures. Extra material available at
http://vigo.ime.unicamp.br/in
Brain serotonin critically contributes to the biological effects of electroconvulsive seizures
Compounds targeting serotonin (5-HT) are widely used as antidepressants. However, the role of 5-HT in mediating the effects of electroconvulsive seizure (ECS) therapy remains undefined. Using Tph2(-/-) mice depleted of brain 5-HT, we studied the effects of ECS on behavior and neurobiology. ECS significantly prolonged the start latency in the elevated O-Maze test, an effect that was abolished in Tph2(-/-) mice. Furthermore, in the absence of 5-HT, the ECS-induced increase in adult neurogenesis and in brain-derived neurotrophic factor signaling in the hippocampus were significantly reduced. Our results indicate that brain 5-HT critically contributes to the neurobiological responses to ECS
The iridium double perovskite Sr2YIrO6 revisited: A combined structural and specific heat study
Recently, the iridate double perovskite SrYIrO has attracted
considerable attention due to the report of unexpected magnetism in this
Ir (5d) material, in which according to the J model, a
non-magnetic ground state is expected. However, in recent works on
polycrystalline samples of the series BaSrYIrO no indication of
magnetic transitions have been found. We present a structural, magnetic and
thermodynamic characterization of SrYIrO single crystals, with emphasis
on the temperature and magnetic field dependence of the specific heat. Here, we
demonstrate the clue role of single crystal X-ray diffraction on the structural
characterization of the SrYIrO double perovskite crystals by reporting
the detection of a supercell, where ,
and are the unit cell dimensions of the reported monoclinic subcell. In
agreement with the expected non-magnetic ground state of Ir (5d) in
SrYIrO, no magnetic transition is observed down to 430~mK. Moreover,
our results suggest that the low temperature anomaly observed in the specific
heat is not related to the onset of long-range magnetic order. Instead, it is
identified as a Schottky anomaly caused by paramagnetic impurities present in
the sample, of the order of \%. These impurities lead to
non-negligible spin correlations, which nonetheless, are not associated with
long-range magnetic ordering.Comment: 20 pages, 10 figure
ART/WORK: Labor, Identity, and Society
Artists, perhaps to emphasize their own dedication to the intellectual and manual skills required for making art, have long been drawn to the theme of labor, both in their depictions of workers and scenes of making. In the late seventeenth century, Dutch paintings frequently portrayed earnest and diligent artisans performing trades at shops or on the streets. Later, rapid economic, social and political changes throughout Europe in the mid-nineteenth century led to a more radical approach to realist representations of labor. This exhibition ART/WORK: Labor, Identity, and Society considers these art-historical precedents to explore the issues of labor in art. More specifically, the student curators investigate the dynamic interplay between labor, gender, and race in the process of industrialization and social transition across various cultures in the late nineteenth and twentieth centuries. ART/WORK highlights thirteen works of art from Gettysburg College’s Fine Art Collection and Special Collections. Posters, prints, and photographs in this exhibition are not simply documents of people and tasks performed within their own particular histories and societies, but are presented as works of art by a diverse group of accomplished makers. [excerpt]https://cupola.gettysburg.edu/artcatalogs/1038/thumbnail.jp
Circle talks as situated experiential learning: Context, identity, and knowledgeability in \u27learning from reflection\u27
This article presents research that used ethnographic and sociolinguistic methods to study ways participants learn through reflection when carried out as a “circle talk.” The data indicate that participants in the event (a) invoked different contextual frames that (b) implicated them in various identity positions, which (c) affected how they could express their knowledge. These features worked together to generate socially shared meanings that enabled participants to jointly achieve conceptualization—the ideational role “reflection” is presumed to play in the experiential learning process. The analysis supports the claim that participants generate new knowledge in reflection, but challenges individualistic and cognitive assumptions regarding how this occurs. The article builds on situated views of experiential learning by showing how knowledge can be understood as socially shared and how learning and identity formation are mutually entailing processes
Pairwise comparison matrices and the error-free property of the decision maker
Pairwise comparison is a popular assessment method either for deriving criteria-weights or for evaluating alternatives according to a given criterion. In real-world applications consistency of the comparisons rarely happens: intransitivity can occur. The aim of the paper is to discuss the relationship between the consistency of the decision maker—described with the error-free property—and the consistency of the pairwise comparison matrix (PCM). The concept of error-free matrix is used to demonstrate that consistency of the PCM is not a sufficient condition of the error-free property of the decision maker. Informed and uninformed decision makers are defined. In the first stage of an assessment method a consistent or near-consistent matrix should be achieved: detecting, measuring and improving consistency are part of any procedure with both types of decision makers. In the second stage additional information are needed to reveal the decision maker’s real preferences. Interactive questioning procedures are recommended to reach that goal
Analysis of pairwise comparison matrices: an empirical research
Pairwise comparison (PC) matrices are used in multi-attribute decision problems (MADM) in order to express the preferences of the decision maker. Our research focused on testing various characteristics of PC matrices. In a controlled experiment with university students (N = 227) we have obtained 454 PC matrices. The cases have been divided into 18 subgroups according to the key factors to be analyzed. Our team conducted experiments with matrices of different size given from different types of MADM problems. Additionally, the matrix elements have been obtained by different questioning procedures differing in the order of the questions. Results are organized to answer five research questions. Three of them are directly connected to the inconsistency of a PC matrix. Various types of inconsistency indices have been applied. We have found that the type of the problem and the size of the matrix had impact on the inconsistency of the PC matrix. However, we have not found any impact of the questioning order. Incomplete PC matrices played an important role in our research. The decision makers behavioral consistency was as well analyzed in case of incomplete matrices using indicators measuring the deviation from the final order of alternatives and from the final score vector
Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions
Altered glucocorticoid receptor (GR) signaling is a postulated mechanism for the pathogenesis of major depression. To mimic the human situation of altered GR function claimed for depression, we generated mouse strains that underexpress or overexpress GR, but maintain the regulatory genetic context controlling the GR gene. To achieve this goal, we used the following: (1) GR-heterozygous mutant mice (GR+/-) with a 50% GR gene dose reduction, and (2) mice overexpressing GR by a yeast artificial chromosome resulting in a twofold gene dose elevation. GR+/- mice exhibit normal baseline behaviors but demonstrate increased helplessness after stress exposure, a behavioral correlate of depression in mice. Similar to depressed patients, GR+/- mice have a disinhibited hypothalamic-pituitary-adrenal (HPA) system and a pathological dexamethasone/corticotropin-releasing hormone test. Thus, they represent a murine depression model with good face and construct validity. Overexpression of GR in mice evokes reduced helplessness after stress exposure, and an enhanced HPA system feedback regulation. Therefore, they may represent a model for a stress-resistant strain. These mouse models can now be used to study biological changes underlying the pathogenesis of depressive disorders. As a first potential molecular correlate for such changes, we identified a downregulation of BDNF protein content in the hippocampus of GR+/- mice, which is in agreement with the so-called neurotrophin hypothesis of depression
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