INCREASING THE AGREEMENT OF DEVELOPMENT OF THE INDUSTRY AND INFRASTRUCTURE IN REGIONS: IMPROVING THE SYSTEM OF STRATEGIC SOFTWARE DOCUMENTS

The system of strategic documents for the development of industry in the Russian Federation is analyzed, its imperfection based on the monitoring of the availability of programs and strategies for the development of the industrial complex in the regions is substantiated. The model for linking strategic documents for the development of industry and infrastructure (using the example of airports) in the region to achieve more efficient economic growth in both sectors is proposed. The emphasis on the inter-level coordination of goals and objectives and the high importance of the relationship with the program documents of the infrastructure sector was placed, and the importance of a key intermediary, the regional authority, was shown. The model can be adapted for different industries, types of infrastructure and various subjects of the federation taking into account the specifics

Chemistry for Sustainable Development 15 (2007) 329-342 Processes of Chemical Weathering of Minerals in Sulphide-Containing Tailing Dumps: Modeling of the Composition of Vadose Water and Secondary Phases

Abstract Thermodynamic model of the oxidative leaching of sulphide-rich tailings from dressing of gold-containing ores (Berikul settlement, West Siberia) is investigated. When calculating the water-rock interactions, we applied some special approaches allowing one to determine the effect of the degree of reaction progress and change of the parameters of the medium (E h , pH) on the composition of the formed secondary minerals that restrain the development of acid drainage at the objects of this kind. Substantiation of several stages of the formation of a technogenic system in time and space is presented, depicting the approach of the system to equilibrium with the environment. The distinguished stages correspond to the zoning of mineral associations described at the object. These associations were formed during 50 years of storing the tailing mounds from the lowest weakly oxidized sulphide parageneses with gypsum and covellite to the capping jarosite-quartz-gypsum zones. The results of modelling provide evidence that an increase in rock affection by atmospheric water brings about the conditions favourable for the formation of the "final" association (goethite and quartz); however, this association is not stable even on the surface of the Berikul tailing dump. It is concluded on the basis of preliminary evaluation that hypergenesis processes in the objects of this kind may proceed hundreds of years till complete depletion of the acid-producing and toxic potential of industry-related wastes

The Dynamics of Plasma Membrane, Metabolism and Respiration (PM-M-R) in Penicillium ochrochloron CBS 123824 in Response to Different Nutrient Limitations-A Multi-level Approach to Study Organic Acid Excretion in Filamentous Fungi.

Filamentous fungi are important cell factories. In contrast, we do not understand well even basic physiological behavior in these organisms. This includes the widespread phenomenon of organic acid excretion. One strong hurdle to fully exploit the metabolic capacity of these organisms is the enormous, highly environment sensitive phenotypic plasticity. In this work we explored organic acid excretion in Penicillium ochrochloron from a new point of view by simultaneously investigating three essential metabolic levels: the plasma membrane H+-ATPase (PM); energy metabolism, in particular adenine and pyridine nucleotides (M); and respiration, in particular the alternative oxidase (R). This was done in strictly standardized chemostat culture with different nutrient limitations (glucose, ammonium, nitrate, and phosphate). These different nutrient limitations led to various quantitative phenotypes (as represented by organic acid excretion, oxygen consumption, glucose consumption, and biomass formation). Glucose-limited grown mycelia were used as the reference point (very low organic acid excretion). Both ammonium and phosphate grown mycelia showed increased organic acid excretion, although the patterns of excreted acids were different. In ammonium-limited grown mycelia amount and activity of the plasma membrane H+-ATPase was increased, nucleotide concentrations were decreased, energy charge (EC) and catabolic reduction charge (CRC) were unchanged and alternative respiration was present but not quantifiable. In phosphate-limited grown mycelia (no data on the H+-ATPase) nucleotide concentrations were still lower, EC was slightly decreased, CRC was distinctly decreased and alternative respiration was present and quantifiable. Main conclusions are: (i) the phenotypic plasticity of filamentous fungi demands adaptation of sample preparation and analytical methods at the phenotype level; (ii) each nutrient condition is unique and its metabolic situation must be considered separately; (iii) organic acid excretion is inversely related to nucleotide concentration (but not EC); (iv) excretion of organic acids is the outcome of a simultaneous adjustment of several metabolic levels to nutrient conditions

Subcomplex Iλ Specifically Controls Integrated Mitochondrial Functions in Caenorhabditis elegans

Complex I dysfunction is a common, heterogeneous cause of human mitochondrial disease having poorly understood pathogenesis. The extensive conservation of complex I composition between humans and Caenorhabditis elegans permits analysis of individual subunit contribution to mitochondrial functions at both the whole animal and mitochondrial levels. We provide the first experimentally-verified compilation of complex I composition in C. elegans, demonstrating 84% conservation with human complex I. Individual subunit contribution to mitochondrial respiratory capacity, holocomplex I assembly, and animal anesthetic behavior was studied in C. elegans by RNA interference-generated knockdown of nuclear genes encoding 28 complex I structural subunits and 2 assembly factors. Not all complex I subunits directly impact respiratory capacity. Subcomplex Iλ subunits along the electron transfer pathway specifically control whole animal anesthetic sensitivity and complex II upregulation, proportionate to their relative impairment of complex I-dependent oxidative capacity. Translational analysis of complex I dysfunction facilitates mechanistic understanding of individual gene contribution to mitochondrial disease. We demonstrate that functional consequences of complex I deficiency vary with the particular subunit that is defective

Adsorption of Cu(II) from aqueous solution using raw peat: preliminary results

Peat is a polar, highly porous material that could have significant applications as an adsorbent for removal of heavy metals from aqueous solutions. Various functional groups in lignin allow such compounds to bind on active sites of peat. The adsorption of Cu (II) from aqueous solutions on peat from the West Siberia was studied in the concentration range of 10–150 mg/L and time variations of 0.25-12 hours. The pH of the solutions varied over a range of 3.2–4.3. The adsorption data could be fitted to a Freundlich adsorption isotherm and the maximum adsorption capacity of peat was determined to be 2.5⋅10-3 mmol/g when the initial concentration for Cu2+ was at its minimum (0.05 mmol/L), and the time of adsorption was 30 minutes

Experimental Studies on Heavy Metal Sorption by Natural Clays Aimed at Drain Water Purification

Abstract Sorption properties of bentonite clays of the Kamalino deposit (Krasnoyarsk Territory) have been studied for the purpose of their possible use for purifying the wastewater of sulphide-containing tailing pits from heavy metal ions. By the example of copper (II), an effect of pH value, of sorbate/sorbent ratio and sorbate concentration increase on the redistribution of metal from model solution to the solid phase. Basing on the data concerning the investigation of water extracts from the substance of the Belovo Zinc Plant (Kemerovo Region) and its wastewaters drain the present object is established to be the source of the acidic mine drain age of the most adverse type (insignificant iron content as well as high heavy metals and sulphate sulphur content). It has been demonstrated efficient results concerning wastewater treatment of the Belovo Zinc Plant tailing pits could be obtained with the use of two-stage purification: first, with the application of calcite, and further via the interaction with a clay sorbent

Thermodynamic modeling in solving some issues of inland saline ecosystems

The purpose of this work was to show some examples of using thermodynamic modeling to understand quantitatively the water-rock interaction processes in salt lakes systems. The systems of small lakes located compactly are convenient to comparative modeling, because this permits minimization of the number of variables in the model (the climatic, geomorphological and geological specifics, water balance in the same watershed area). Nevertheless, it turns out that each lake is a relatively autonomous system (natural biogeocenosis, formed as a result of diagenesis). Due to the conjugate processes of biogenic and inorganic interactions, they are in a steady state, which has been fixed during the geochemical sampling in the field

Modeling scenarios of extreme situations in the energy sector caused by cyber threats

The paper considers the violation of cybersecurity as a possibility of a real impact (intentional or accidental) from cyberspace on the physical infrastructure of a digital energy facility. In energy security studies, such impacts are considered as extreme situations, including critical and emergency situations. A model of scenarios of extreme situations in the energy sector caused by cyber threats using Bayesian Belief Network and the stages of modeling are considered in more detail. The five main stages are i) modeling cyber threats vectors of intrusion and advance towards the target asset; ii) modeling an attack on a target system in the technological segment of the local area network; iii) modeling technogenic threats to energy security caused by cyber threats; iv) modeling consequences at the level of the facility system; v) modeling consequences at the level of the infrastructure. This approach allows one to build cause and effect relationships from vulnerabilities in the cyber environment to the consequences. Modeling stages are aimed at increasing the level of cyber situational awareness, which, in turn, related with energy security issues