Joaquín Rieta y el teatro de la Banda Primitiva de Llíria

Joaquín Rieta Síster (Valencia, 1897-1982) es uno de los principales exponentes de la arquitectura valenciana de las décadas centrales del siglo XX. Su reconocimiento se circunscribe principalmente a las obras racionalistas de la década de 1930. Menos conocida es, sin embargo, su “otra” arquitectura, la construida después de la Guerra Civil, ignorada con frecuencia desde la óptica de una historiografía excluyente que ha puesto el valor en la modernidad. Dentro de este contexto podemos situar el teatro de la Banda Primitiva de Llíria (1950-1951). El presente estudio comienza encuadrando la figura del arquitecto y académico, seguida de una breve recensión de la sociedad comitente, la prestigiosa banda bicentenaria valenciana. A continuación, el discurso se centra en el análisis arquitectónico de los dos proyectos del teatro, y de su habilidosa reconducción de la mano de Rieta, para finalmente poner en valor su realidad física como bien patrimonial plenamente activo. Al interés arquitectónico y social se suma el hecho de ser el único de los teatros construidos por Rieta que se conserva en buen estado y con escasas alteraciones

PSA Response to Lenalidomide Therapy in a Pre-Treated Patient with Metastatic Prostate Cancer Refractory to Hormones and Chemotherapy: A Case Report

Hormone-resistant prostate cancer (HRPC) occurs when prostate cancer is no longer responsive to hormone therapy. Treatment options are limited, and there is a clear necessity for therapies that improve outcome. Preclinical and clinical evidence supports the role of the immunomodulatory agent lenalidomide in HRPC. In this paper, we report that lenalidomide showed antitumoral activity in a patient with HRPC and bone metastases pre-treated with chemotherapy, decreased the PSA level and improved the patient's health status for the first 5 months. It is important to emphasize that it was not associated with hematologic toxicity

Thermal Analysis of the Solar Orbiter PHI Electronics Unit

This paper presents the thermal design of the electronics unit of the instrument Polarimetric Helioseismic Imager, onboard the European Space Agency mission Solar Orbiter. The thermal design procedure, along with the problems encountered during this design phase, and the solutions found to fix them are described, proving in this way the thermal feasibility and robustness of the unit. Its final thermal behaviour, obtained from thermal analyses correlated with data from thermal tests performed in a vacuum environment, is presented

Stability improvement of isolated multiple-output DC/DC converter using coupled inductors

Coupling output inductors is a very popular solution when designing a multiple-output DC/DC system. Space-borne circuits are one of the areas where a custom DC/DC converter design with coupled inductors could be preferred to have a detailed design of all variables. Output voltage regulation can be improved using coupled output inductors on a multiple-output DC/DC converter, and, as demonstrated in this paper, it provides an enhanced stability. This paper presents the small signal analysis of a push-pull converter with seven outputs having all its output inductors coupled together and compares it theoretically to the uncoupled version to demonstrate the stability improvement. The theoretical results are validated by simulating a linear model of the circuit and measuring the frequency response on an experimental prototype. Design guidelines and additional benefits of output-coupled inductors are also listed

Durable complete remission of a brainstem glioma treated with a combination of bevacizumab and cetuximab

Treatment of a relapsed glioma is a clinical challenge nowadays. New active treatments are required to treat these difficult diseases. Here we present a durable complete remission of a relapsed glioblastoma that has achieved a complete radiologic response with the combination of cetuximab and bevacizumab, in a third-line setting, that has offered a progression-free survival of 20 months. We consider here both potential mechanisms for the explanation of this result. First, the potential target of the cancer stem cells (CSCs) with these two antibodies, and second, the potential recruitment of the immune system to directly pursue the CSCs

A first rapid synoptic magnetic field map using SDO/HMI and SO/PHI data

Context. Traditionally, the observation time needed to build synoptic maps of the solar magnetic field is bound to the 27 days of a full Carrington rotation due to the single viewpoint from Earth. Aims. Our aim is to reduce this observation time to 13.5 days by combining magnetograms from two vantage points, 180 apart in longitude in the ideal case. Methods. We combined observations taken by the Polarimetric and Helioseismic Imager (SO/PHI) during the superior conjunction of the Solar Orbiter in February 2021 with data from the Helioseismic and Magnetic Imager (SDO/HMI) and constructed a synoptic map of the line-of-sight magnetic field of CR 2240. Resuls. The result is the first multi-view synoptic map using SDO/HMI and SO/PHI data from an observing period of only 16 days. Comparing the multi-view synoptic map to the standard synoptic map of SDO/HMI shows a significant amount of magnetic evolution between the dates on which the two instruments observed the same solar longitudes. The changed magnetic field was caught by the multi-view synoptic map but would have been missed by a standard synoptic map. Conclusions. Our results demonstrate that multi-view synoptic maps provide a new method to obtain a more instantaneous map of the magnetic field over the entire solar surface

Determination of the SO/PHI-HRT wavefront degradation using multiple defocused images

Context. The Polarimetric and Helioseismic Imager on board the Solar Orbiter mission (SO/PHI) offers refocusing capabilities to cope with the strongly varying thermal environment of the optical system along the spacecraft's elliptical orbit. The series of images recorded during in-flight focus calibrations can be employed for phase diversity analyses. Aims. In this work we infer the wavefront degradation caused by the thermo-optical effects in the High Resolution Telescope (HRT) from images taken during the fine and coarse focus scans performed in the commissioning phase of the instrument. The difference between these two series of images are mainly related to the employed defocused step (smaller for the fine scans) and the signal-to-noise ratio (higher for the coarse scans). We use the retrieved wavefronts to reconstruct the original scene observed during the calibration of the instrument. Methods. We applied a generalized phase diversity algorithm that allowed us to use several images taken with different amounts of defocus to sense the wavefront degradation caused by the instrument. The algorithm also uses information from both the inferred wavefront and the series of images to restore the solar scene. Results. We find that most of the retrieved Zernike coefficients tend to converge to the same value when increasing the number of images employed for PD for both the fine and the coarse focusing scans. The restored scenes also show signs of convergence, and the merit function is minimized more as K increases. Apart from a defocus, the inferred wavefronts are consistent for the two datasets (lambda/10 - lambda/11). For the fine scan images, the quiet-sun contrast improves from 4.5% for the original focused image up to about 10%. For the coarse scan images, the contrast of the restored scene is as high as 11%

Coronal voids and their magnetic nature

Context. Extreme ultraviolet (EUV) observations of the quiet solar atmosphere reveal extended regions of weak emission compared to the ambient quiescent corona. The magnetic nature of these coronal features is not well understood. Aims. We study the magnetic properties of the weakly emitting extended regions, which we name coronal voids. In particular, we aim to understand whether these voids result from a reduced heat input into the corona or if they are associated with mainly unipolar and possibly open magnetic fields, similar to coronal holes. Methods. We defined the coronal voids via an intensity threshold of 75% of the mean quiet-Sun (QS) EUV intensity observed by the high-resolution EUV channel (HRIEUV) of the Extreme Ultraviolet Imager on Solar Orbiter. The line-of-sight magnetograms of the same solar region recorded by the High Resolution Telescope of the Polarimetric and Helioseismic Imager allowed us to compare the photospheric magnetic field beneath the coronal voids with that in other parts of the QS. Results. The coronal voids studied here range in size from a few granules to a few supergranules and on average exhibit a reduced intensity of 67% of the mean value of the entire field of view. The magnetic flux density in the photosphere below the voids is 76% (or more) lower than in the surrounding QS. Specifically, the coronal voids show much weaker or no network structures. The detected flux imbalances fall in the range of imbalances found in QS areas of the same size. Conclusions. We conclude that coronal voids form because of locally reduced heating of the corona due to reduced magnetic flux density in the photosphere. This makes them a distinct class of (dark) structure, different from coronal holes

The ratio of horizontal to vertical displacement in solar oscillations estimated from combined SO/PHI and SDO/HMI observations

In order to make accurate inferences about the solar interior using helioseismology, it is essential to understand all the relevant physical effects on the observations. One effect to understand is the (complex-valued) ratio of the horizontal to vertical displacement of the p- and f-modes at the height at which they are observed. Unfortunately, it is impossible to measure this ratio directly from a single vantage point, and it has been difficult to disentangle observationally from other effects. In this paper we attempt to measure the ratio directly using 7.5 h of simultaneous observations from the Polarimetric and Helioseismic Imager on board Solar Orbiter and the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory. While image geometry problems make it difficult to determine the exact ratio, it appears to agree well with that expected from adiabatic oscillations in a standard solar model. On the other hand it does not agree with a commonly used approximation, indicating that this approximation should not be used in helioseismic analyses. In addition, the ratio appears to be real-valued

Reconstruction of total solar irradiance variability as simultaneously apparent from Solar Orbiter and Solar Dynamics Observatory

Solar irradiance variability has been monitored almost exclusively from the Earth's perspective. We present a method to combine the unprecedented observations of the photospheric magnetic field and continuum intensity from outside the Sun-Earth line, which is being recorded by the Polarimetric and Helioseismic Imager on board the Solar Orbiter mission (SO/PHI), with solar observations recorded from the Earth's perspective to examine the solar irradiance variability from both perspectives simultaneously. Taking SO/PHI magnetograms and continuum intensity images from the cruise phase of the Solar Orbiter mission and concurrent observations from the Helioseismic and Magnetic Imager onboard the Solar Dynamics Observatory (SDO/HMI) as input into the SATIRE-S model, we successfully reconstructed the total solar irradiance variability as apparent from both perspectives. In later stages of the SO mission, the orbital plane will tilt in such a way as to bring the spacecraft away from the ecliptic to heliographic latitudes of up to 33°. The current study sets the template for the reconstruction of solar irradiance variability as seen from outside the ecliptic from data that SO/PHI is expected to collect from such positions. Such a reconstruction will be beneficial to factoring inclination into how the brightness variations of the Sun compare to those of other cool stars, whose rotation axes are randomly inclined