93 research outputs found

    Разработка веб-приложения для автоматического построения отчетов на основе системы компьютерной вёрстки TeX

    Get PDF
    Объект исследования: система компьютерной верстки TeX и её использование для автоматизации построения отчётов. Цель работы: разработка веб-приложения для работы с системой компьютерной вёрстки TeX для автоматизации построения отчётов по заранее заданным шаблонам. Область применения: компьютерная вёрстка, электронный документооборот, стандартизация электронной документации. Экономическая значимость работы: сокращается время и стоимость рабочих часов на подготовку отчётов, увеличивается производительность работы, сокращается расход бумаги.Object of study: computer typesetting system TeX and its use for automation of the reporting. Goal: to develop a web application to work with the computer typesetting system TeX to automate reporting by pre-defined templates. Applications: desktop publishing, electronic documentation, standardization of electronic documentation. The economic significance of the work: it reduces the time and cost of working hours in preparation of reports increased productivity, reduced paper consumption

    A typhoid fever outbreak in a slum of South Dumdum municipality, West Bengal, India, 2007: Evidence for foodborne and waterborne transmission

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>In April 2007, a slum of South Dumdum municipality, West Bengal reported an increase in fever cases. We investigated to identify the agent, the source and to propose recommendations.</p> <p>Methods</p> <p>We defined a suspected case of typhoid fever as occurrence of fever for ≥ one week among residents of ward 1 of South Dumdum during February – May 2007. We searched for suspected cases in health care facilities and collected blood specimens. We described the outbreak by time, place and person. We compared probable cases (Widal positive >= 1:80) with neighbourhood-matched controls. We assessed the environment and collected water specimens.</p> <p>Results</p> <p>We identified 103 suspected cases (Attack rate: 74/10,000, highest among 5–14 years old group, no deaths). Salmonella (enterica) Typhi was isolated from one of four blood specimens and 65 of 103 sera were >= 1:80 Widal positive. The outbreak started on 13 February, peaked twice during the last week of March and second week of April and lasted till 27 April. Suspected cases clustered around three public taps. Among 65 probable cases and 65 controls, eating milk products from a sweet shop (Matched odds ratio [MOR]: 6.2, 95% confidence interval [CI]: 2.4–16, population attributable fraction [PAF]: 53%) and drinking piped water (MOR: 7.3, 95% CI: 2.5–21, PAF-52%) were associated with illness. The sweet shop food handler suffered from typhoid in January. The pipelines of intermittent non-chlorinated water supply ran next to an open drain connected with sewerage system and water specimens showed faecal contamination.</p> <p>Conclusion</p> <p>The investigation suggested that an initial foodborne outbreak of typhoid led to the contamination of the water supply resulting in a secondary, waterborne wave. We educated the food handler, repaired the pipelines and ensured chlorination of the water.</p

    Выбор участка эксплуатационного объекта для применения гидродинамических методов увеличения нефтеотдачи в процессе разработки месторождений

    Get PDF
    Объектом исследования являются технологии гидродинамических методов увеличения нефтеотдачи. Цель исследования – обоснование применения гидродинамических методов увеличения нефтеотдачи на эксплуатационных объектах нефтяных месторождений. В процессе исследования были подробно рассмотрены технологии гидродинамических методов нефтеотдачи, применяемых на нефтяных месторождениях, а также рассмотрена эффективность применения от внедрения технологий в процесс эксплуатации месторождения. Проведен обзор применения различных методов и анализ их эффективности применения. Проанализирован метод комбинированного нестационарного заводнения.The object of the research is the technologies of hydrodynamic methods of increasing oil recovery. The purpose of the study is to substantiate the use of hydrodynamic methods for enhancing oil recovery at production facilities of oil fields. In the course of the study, the technologies of hydrodynamic methods of oil recovery used in oil fields were considered in detail, and the effectiveness of the application from the introduction of technologies into the process of operating the field was considered. A review of the application of various methods and an analysis of their effectiveness are carried out. The method of combined non-stationary waterflooding is analyzed

    International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

    Get PDF
    Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist

    Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

    Get PDF
    corecore