Equilibrium and volumetric data and model development of coal fluids

The long term goal of our efforts is to develop accurate predictive methods for description of equilibrium phase properties for a variety of types of mixtures and operating conditions. The specific objectives of the work specified herein include: (1) development of an experimental facility having the capability to provide data on equilibrium phase compositions (solubilities) and liquid densities, and doing so with greater accuracy and speed than our previous facility, (2) measurement of equilibrium phase properties for systematically-selected mixtures-specifically those containing important solute gases (such as hydrogen, carbon monoxide, methane, ethane, carbonyl sulfide, ammonia) in a series of heavy paraffinic, naphthenic and aromatic solvents (e.g., n-decane, n-eicosane, n-octacosane, n-hexatriacontane, cyclohexane, Decalin, perhydrophenanthrene, perhydropyrene, benzene, naphthalene, phenanthrene, pyrene), (3) testing/development of correlation frameworks for representing the phase behavior of fluids of the type encountered in coal conversion processes, and (4) generalization of parameters in the correlation frameworks to enable accurate predictions for systems of the type studied, permitting predictions to be made for systems and conditions other than those for which experimental data are available

Equilibrium and volumetric data and model development for coal fluids

During the present reporting period, the solubilities of hydrogen in benzene were measured at temperatures from 323.2 to 423.2 K (122.0 to 302.0[degrees]F) and pressures to 15.7 MPa (2281 psia). These data are described with root-mean-square errors typically less than 0.001 in mole fraction by the Soave-Redlich-Kwong and Peng-Robinson equations of state when a single interaction parameter, C[sub ij], is used for each isother

Are pathogenic leptospira species agents of community-acquired pneumonia? case reports of leptospirosis presenting as pneumonia

We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acutephase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis

Разработка веб-приложения для автоматического построения отчетов на основе системы компьютерной вёрстки TeX

Объект исследования: система компьютерной верстки TeX и её использование для автоматизации построения отчётов. Цель работы: разработка веб-приложения для работы с системой компьютерной вёрстки TeX для автоматизации построения отчётов по заранее заданным шаблонам. Область применения: компьютерная вёрстка, электронный документооборот, стандартизация электронной документации. Экономическая значимость работы: сокращается время и стоимость рабочих часов на подготовку отчётов, увеличивается производительность работы, сокращается расход бумаги.Object of study: computer typesetting system TeX and its use for automation of the reporting. Goal: to develop a web application to work with the computer typesetting system TeX to automate reporting by pre-defined templates. Applications: desktop publishing, electronic documentation, standardization of electronic documentation. The economic significance of the work: it reduces the time and cost of working hours in preparation of reports increased productivity, reduced paper consumption

Factors Associated with High Prevalence of Intestinal Protozoan Infections among Patients in Sana'a City, Yemen

Intestinal protozoan diseases in Yemen are a significant health problem with prevalence ranging from 18% to 27%. The present study is a cross-sectional study aimed at determining the factors associated with the high prevalence of intestinal protozoan infections among patients seeking health care in Sana'a City, the capital of Yemen. (0.4%). Multivariate analysis using forward stepwise logistic regression based on intestinal protozoan infections showed that contact with animals (OR = 1.748, 95% CI = 1.168–2.617) and taking bath less than twice a week (OR = 1.820, 95% CI = 1.192–2.779) were significant risk factors of protozoan infections. infections being most common. Statistical analysis indicated that low personal hygiene and contact with animals were important predictors for intestinal protozoan infections. As highlighted in this study, in order to effectively reduce these infections, a multi-sectoral effort is needed. Preventive measures should include good hygienic practices, good animal husbandry practices, heightened provision of educational health programs, health services in all governorates including rural areas. Furthermore, it is also essential to find radical solutions to the recent water crises in Yemen

A typhoid fever outbreak in a slum of South Dumdum municipality, West Bengal, India, 2007: Evidence for foodborne and waterborne transmission

<p>Abstract</p> <p>Background</p> <p>In April 2007, a slum of South Dumdum municipality, West Bengal reported an increase in fever cases. We investigated to identify the agent, the source and to propose recommendations.</p> <p>Methods</p> <p>We defined a suspected case of typhoid fever as occurrence of fever for ≥ one week among residents of ward 1 of South Dumdum during February – May 2007. We searched for suspected cases in health care facilities and collected blood specimens. We described the outbreak by time, place and person. We compared probable cases (Widal positive >= 1:80) with neighbourhood-matched controls. We assessed the environment and collected water specimens.</p> <p>Results</p> <p>We identified 103 suspected cases (Attack rate: 74/10,000, highest among 5–14 years old group, no deaths). Salmonella (enterica) Typhi was isolated from one of four blood specimens and 65 of 103 sera were >= 1:80 Widal positive. The outbreak started on 13 February, peaked twice during the last week of March and second week of April and lasted till 27 April. Suspected cases clustered around three public taps. Among 65 probable cases and 65 controls, eating milk products from a sweet shop (Matched odds ratio [MOR]: 6.2, 95% confidence interval [CI]: 2.4–16, population attributable fraction [PAF]: 53%) and drinking piped water (MOR: 7.3, 95% CI: 2.5–21, PAF-52%) were associated with illness. The sweet shop food handler suffered from typhoid in January. The pipelines of intermittent non-chlorinated water supply ran next to an open drain connected with sewerage system and water specimens showed faecal contamination.</p> <p>Conclusion</p> <p>The investigation suggested that an initial foodborne outbreak of typhoid led to the contamination of the water supply resulting in a secondary, waterborne wave. We educated the food handler, repaired the pipelines and ensured chlorination of the water.</p

Выбор участка эксплуатационного объекта для применения гидродинамических методов увеличения нефтеотдачи в процессе разработки месторождений

Объектом исследования являются технологии гидродинамических методов увеличения нефтеотдачи. Цель исследования – обоснование применения гидродинамических методов увеличения нефтеотдачи на эксплуатационных объектах нефтяных месторождений. В процессе исследования были подробно рассмотрены технологии гидродинамических методов нефтеотдачи, применяемых на нефтяных месторождениях, а также рассмотрена эффективность применения от внедрения технологий в процесс эксплуатации месторождения. Проведен обзор применения различных методов и анализ их эффективности применения. Проанализирован метод комбинированного нестационарного заводнения.The object of the research is the technologies of hydrodynamic methods of increasing oil recovery. The purpose of the study is to substantiate the use of hydrodynamic methods for enhancing oil recovery at production facilities of oil fields. In the course of the study, the technologies of hydrodynamic methods of oil recovery used in oil fields were considered in detail, and the effectiveness of the application from the introduction of technologies into the process of operating the field was considered. A review of the application of various methods and an analysis of their effectiveness are carried out. The method of combined non-stationary waterflooding is analyzed

Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

Leptospirosis is a bacterial disease that is mainly spread by rodents and other small mammals. Transmission frequently occurs in (sub-) tropical countries, where environmental circumstances are most favourable. Severe leptospirosis can cause bleeding and vital organ dysfunction. An exaggerated immune response is thought to play an important role in the pathophysiology of leptospirosis. Soluble ST2 (sST2) is thought to inhibit negative regulatory pathways of this response. Soluble ST2 is produced by cells that surround, for example, blood vessels, and several of these blood cells play an important part in the host immune response. In an observational study, we measured the extent of sST2 release in patients suffering from severe leptospirosis. We found that patients that died from leptospirosis displayed higher levels of sST2. Moreover, from this study we have seen that sST2 levels were associated with bleeding, whereas other markers of infection were not. In an experiment, we showed that (white) blood cells did not seem to be the source of sST2 production. Damage to blood vessels is likely to cause bleeding in leptospirosis patients, exposing sST2 producing cells like fibroblasts to the blood stream. Hence, we believe that sST2 may be used as a marker for tissue damage in patients suffering from severe leptospirosis

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist