16 research outputs found

    Application of HPM to Solve Unsteady Squeezing Flow of a Second-Grade Fluid between Circular Plates

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    In this article, Homotopy Perturbation Method (HPM) is used to provide two approximate solutions to the nonlinear differential equation that describes the behaviour for the unsteady squeezing flow of a second grade fluid between circular plates. Comparing results between approximate and numerical solutions shows that our results are capable to provide an accurate solution and are extremely efficient

    Classical Perturbation Method for the Solution of a Model of Diffusion and Reaction

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    In this paper, we employ perturbation method (PM) to solve nonlinear problems. As case study PM is employed to obtain approximate solutions for the nonlinear differential equation that models the diffusion and reaction in porous catalysts. We find that the square residual error (S.R.E) of our solutions is in the range and this requires only the third order approximation of PM, which shows the effectiveness of the method

    A High Accurate Approximation for a Galactic Newtonian Nonlinear Model Validated by Employing Observational Data

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    This article proposes Perturbation Method (PM) to solve nonlinear problems. As case study PM is employed to provide a detailed study of a nonlinear galactic model. Our approach is rather elementary and seeks to explain as much detail as possible the material of this work.In particular our solution gives rise qualitatively, to the known flat rotation curves. In fact, we compare the numerical solution and the obtained approximation by employing observational data proving the validity and high accuracy of the model under study

    Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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    Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19

    Marine Biodiversity in the Caribbean: Regional Estimates and Distribution Patterns

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    This paper provides an analysis of the distribution patterns of marine biodiversity and summarizes the major activities of the Census of Marine Life program in the Caribbean region. The coastal Caribbean region is a large marine ecosystem (LME) characterized by coral reefs, mangroves, and seagrasses, but including other environments, such as sandy beaches and rocky shores. These tropical ecosystems incorporate a high diversity of associated flora and fauna, and the nations that border the Caribbean collectively encompass a major global marine biodiversity hot spot. We analyze the state of knowledge of marine biodiversity based on the geographic distribution of georeferenced species records and regional taxonomic lists. A total of 12,046 marine species are reported in this paper for the Caribbean region. These include representatives from 31 animal phyla, two plant phyla, one group of Chromista, and three groups of Protoctista. Sampling effort has been greatest in shallow, nearshore waters, where there is relatively good coverage of species records; offshore and deep environments have been less studied. Additionally, we found that the currently accepted classification of marine ecoregions of the Caribbean did not apply for the benthic distributions of five relatively well known taxonomic groups. Coastal species richness tends to concentrate along the Antillean arc (Cuba to the southernmost Antilles) and the northern coast of South America (Venezuela – Colombia), while no pattern can be observed in the deep sea with the available data. Several factors make it impossible to determine the extent to which these distribution patterns accurately reflect the true situation for marine biodiversity in general: (1) highly localized concentrations of collecting effort and a lack of collecting in many areas and ecosystems, (2) high variability among collecting methods, (3) limited taxonomic expertise for many groups, and (4) differing levels of activity in the study of different taxa

    Optical Fiber Sensor For Pressure Based On Multimode Interference As Sensitive Element

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    The experimental results of applications on a novel intrinsic fiber optic pressure sensor based on multimode interference are presented. The sensitive element consists in a SM-MM-SM (MMI) fiber structure embedded in a membrane. © 2010 Optical Society of America

    Phenolic composition changes of processed common beans: Their antioxidant and anti-inflammatory effects in intestinal cancer cells

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    © 2015 Elsevier Ltd. Four varieties of common beans, Negro 8025 (N), Bayo Victoria (BV), Pinto Durango (PD), and Pinto Saltillo (PS) were evaluated and compared for phenolic composition, antioxidant activity and anti-inflammatory effects by in vitro human intestinal cell model. Beans were processed by canning and boiling in open pot. Acetone/Water extracts were analyzed for phenolic composition by HPLC-PAD and HPLC-MS, screened for antioxidant activities, as lipid peroxidation inhibition and chelating capacities by inhibition of deoxi-D-ribose degradation. It was investigated their anticarcinogenic effect by inhibiting cell proliferation, decreasing interleukin-8 (IL-8), modulating interleukin-10 (IL-10), inhibiting tumor necrosis factor alpha (TNFα) and regulating nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κβ). Canning induced antioxidant compounds in order N. > PD > BV > PS associated with potential for scavenging hydroxyl radicals and metal chelating capacities. Effect of cooking on bioactive compounds was cultivar dependent, being more quantitative than qualitative due to release of bonded phenolics. Inhibition of cyclooxygenase-2 (COX-2), TNFα and NF-κβ was observed, and the induced expression of IL-10. Both effects were also cultivar and process dependent, particularly in PD beans.Peer Reviewe
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