Alterações neurológicas associadas a SARS-CoV-2: uma revisão de literatura: Associated neurological changes the SARS-CoV-2: a literature review

Introdução. A doença comumente conhecida por COVID-19 é capaz de ser encontrada em todos os órgãos e sistemas. Contudo o SNC pode ser afetado de forma que cause danos significativos aos que foram acometidos pela mesma. Desta forma, este trabalho é uma revisão acerca dos achados e suas manifestações para que possamos no futuro triar, buscar e analisar fatores neurologicamente afetados. Objetivo. Analisar e revisar matérias que possam auxiliar no detalhamento acerca de alterações neurológicas oriundas da COVID-19. Método. A estratégia utilizada contou com estudos, tendo por base uma análise em plataformas como o Google Acadêmico, PubMed, SciELO, Medical Subject Heading (MeSH), nas quais cada fonte de dados contou com um estudo acerca dos títulos, assuntos e tipos específicos na língua portuguesa e inglesa. Resultados. Foi possível ao longo de 16 artigos analisados, observar que grande parte da população analisada teve alterações, sejam elas leves como mialgia, disfunções de olfato e paladar, podendo a ter alterações graves como o Acidente Vascular Cerebral (AVC). Além disso, foi possível observar que pacientes com morbidades como a DM e a HAS tiveram maiores propensões a doenças cerebrovasculares. Conclusão. Este estudo oferece uma nova forma de pensar e analisar as alterações causadas pela COVID-19, associado com as alterações neurológicas. Com isso, podemos ajudar a identificar e classificar as possíveis alterações, a fim de auxiliar no combate a alterações severas

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets. Notably, the Guidelines contain helpful tables highlighting phenotypes and key differences between human and murine cells. Another useful feature of this edition is the flow cytometry analysis of clinical samples with examples of flow cytometry applications in the context of autoimmune diseases, cancers as well as acute and chronic infectious diseases. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid. All sections are written and peer‐reviewed by leading flow cytometry experts and immunologists, making this edition an essential and state‐of‐the‐art handbook for basic and clinical researchers.DFG, 389687267, Kompartimentalisierung, Aufrechterhaltung und Reaktivierung humaner Gedächtnis-T-Lymphozyten aus Knochenmark und peripherem BlutDFG, 80750187, SFB 841: Leberentzündungen: Infektion, Immunregulation und KonsequenzenEC/H2020/800924/EU/International Cancer Research Fellowships - 2/iCARE-2DFG, 252623821, Die Rolle von follikulären T-Helferzellen in T-Helferzell-Differenzierung, Funktion und PlastizitätDFG, 390873048, EXC 2151: ImmunoSensation2 - the immune sensory syste

Retroperitoneoscopy to extract dropped gallstones after laparoscopic cholecystectomy

Case Reports; Journal Article;Complications resulting from gallstones left in the peritoneal cavity are most often reported after laparoscopic treatment of cholelitiasis. Gallstones are frequently dropped in the posterior subhepatic space, which can lead to the development of abscesses that usually require laparotomy for extraction of the stones. We present a novel technique for treating collections associated with dropped gallstones, using retroperitoneoscopy with two 10-mm ports after ultrasound localization of the abscess. We carried out this procedure in two patients and successfully extracted the gallstones without postoperative complications or recurrences. We consider this approach to be technically feasible, safe, and effective. It avoids the usual inefficacy of simple percutaneous drainage of these collections and the complications associated with the drainage of intra-abdominal abscesses by laparotomy.Ye

Guía de Biovigilancia de Órganos, Células y Tejidos de Andalucía

Coordinación Autonómica de Trasplantes. Dirección General de Asistencia Sanitaria. Servicio Andaluz de SaludYesLa presente Guía ha sido elaborada por el Grupo de Trabajo de Biovigilancia de Andalucía con el objetivo de unificar y mejorar la actuación de todos los profesionales que intervienen en el proceso de donación y trasplantes de órganos, células y tejidos, y recoge el circuito a seguir en caso de detectar un incidente o una reacción adversa relacionada con el uso terapéutico de células y tejidos humanos y el trasplante de órganos. Incluye un listado de posibles incidentes y reacciones adversas elaborado por el grupo de trabajo de Biovigilancia, con la colaboración y aportaciones de profesionales expertos y consensuado con diferentes Equipos Andaluces de trasplantes de órganos y la Comisión de trasplantes de progenitores hematopoyéticos de Andalucía

Trasplante hepático: proceso asistencial integrado. 2ª ed

Publicado en la página web de la Consejería de Salud: www.juntadeandalucia.es/salud (Consejería de Salud / Profesionales / Nuestro Compromiso por la Calidad / Procesos Asistenciales Integrados)YesConjunto de actividades secuenciales para el tratamiento médico-quirúrgico al paciente afecto de una enfermedad hepática crónica avanzada o aguda irreversible, que es evaluado e incluido en lista de espera para sustituir su hígado enfermo por un hígado sano, parcial o totalmente, procedente de un donante cádaver o un donante vivo y, posteriormente, ser seguido de manera continua, con el objetivo de normalizar la función hepática y mejorar su calidad de vida

Transcatheter Mitral Repair for Functional Mitral Regurgitation According to Left Ventricular Function: A Real-Life Propensity-Score Matched Study

Background: Transcatheter mitral valve repair (TMVR) could improve survival in functional mitral regurgitation (FMR), but it is necessary to consider the influence of left ventricular ejection fraction (LVEF). Therefore, we compare the outcomes after TMVR with Mitraclip® between two groups according to LVEF. Methods: In an observational registry study, we compared the outcomes in patients with FMR who underwent TMVR with and without LVEF <30%. The primary endpoint was the combined one-year all-cause mortality and unplanned hospital readmissions due to HF. The secondary end-points were New York Heart Association (NYHA) functional class and mitral regurgitation (MR) severity. Propensity-score matching was used to create two groups with the same baseline characteristics, except for baseline LVEF. Results: Among 535 FMR eligible patients, 144 patients with LVEF <30% (group 1) and 144 with LVEF >30% (group 2) had similar propensity scores and were included in the analyses. The primary study endpoint was significantlly higher in group 1 (33.3% vs. 9.4%, p = 0.002). There was a maintained improvement in secondary endpoints without significant differences among groups. Conclusion: FMR patients with LVEF <30% treated with MitraClip® had higher mortality and readmissions than patients with LVEF ≥30% treated with the same device. However, both groups improved the NYHA functional class and MR severity

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza A, Chang H‐D, Radbruch A, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). European Journal of Immunology. 2021;51(12):2708-3145.The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets. Notably, the Guidelines contain helpful tables highlighting phenotypes and key differences between human and murine cells. Another useful feature of this edition is the flow cytometry analysis of clinical samples with examples of flow cytometry applications in the context of autoimmune diseases, cancers as well as acute and chronic infectious diseases. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid. All sections are written and peer-reviewed by leading flow cytometry experts and immunologists, making this edition an essential and state-of-the-art handbook for basic and clinical researchers

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets. Notably, the Guidelines contain helpful tables highlighting phenotypes and key differences between human and murine cells. Another useful feature of this edition is the flow cytometry analysis of clinical samples with examples of flow cytometry applications in the context of autoimmune diseases, cancers as well as acute and chronic infectious diseases. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid. All sections are written and peer-reviewed by leading flow cytometry experts and immunologists, making this edition an essential and state-of-the-art handbook for basic and clinical researchers.ISSN:0014-2980ISSN:1521-414

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets. Notably, the Guidelines contain helpful tables highlighting phenotypes and key differences between human and murine cells. Another useful feature of this edition is the flow cytometry analysis of clinical samples and respective applications of flow cytometry in the context of a variety of autoimmune diseases, cancers as well as acute and chronic infectious diseases such as COVID-19. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid. All sections are written and peer-reviewed by leading flow cytometry experts and immunologists, making this edition an essential and state-of-the-art handbook for basic and clinical researchers