The Evolution of Luminous Compact Blue Galaxies: Disks or Spheroids?

Luminous compact blue galaxies (LCBGs) are a diverse class of galaxies characterized by high luminosity, blue color, and high surface brightness that sit at the critical juncture of galaxies evolving from the blue to the red sequence. As part of our multi-wavelength survey of local LCBGs, we have been studying the HI content of these galaxies using both single-dish telescopes and interferometers. Our goals are to determine if single-dish HI observations represent a true measure of the dynamical mass of LCBGs and to look for signatures of recent interactions that may be triggering star formation in LCBGs. Our data show that while some LCBGs are undergoing interactions, many appear isolated. While all LCBGs contain HI and show signatures of rotation, the population does not lie on the Tully-Fisher relation nor can it evolve onto it. Furthermore, the HI maps of many LCBGs show signatures of dynamically hot components, suggesting that we are seeing the formation of a thick disk or spheroid in at least some LCBGs. There is good agreement between the HI and H-alpha kinematics for LCBGs, and both are similar in appearance to the H-alpha kinematics of high redshift star-forming galaxies. Our combined data suggest that star formation in LCBGs is primarily quenched by virial heating, consistent with model predictions.Comment: 4 pages, 2 figures, to appear in the proceedings of IAU Symposium 277, "Tracing the Ancestry of Galaxies on the Land of our Ancestors", eds. C. Carignan, K.C. Freeman, and F. Combe

Validation of the Equations Used in Determining Dry Matter Intake, and Metabolizable Protein Requirements for Finishing Lambs as used in the Sheep Companion Module to BRaNDS

The growth equations published in the 2006 NRC “Nutrient Requirements of Small Ruminants” along with the additions added to these equations when used in the Sheep Companion Module to BRaNDS appear to provide reasonable estimations of performance of feeder lambs

Human Factors Certification of Advanced Aviation Technologies

Proceedings of the Human Factors Certification of Advanced Aviation Technologies Conference held at the Chateau de Bonas, near Toulouse, France, 19-23 July 1993

Evolution of Coronal Magnetic Field Parameters during X5.4 Solar Flare

The coronal magnetic field over NOAA Active Region 11,429 during a X5.4 solar flare on 7 March 2012 is modeled using optimization based Non-Linear Force-Free Field extrapolation. Specifically, 3D magnetic fields were modeled for 11 timesteps using the 12-min cadence Solar Dynamics Observatory (SDO) Helioseismic and Magnetic Imager photospheric vector magnetic field data, spanning a time period of 1 hour before through 1 hour after the start of the flare. Using the modeled coronal magnetic field data, seven different magnetic field parameters were calculated for 3 separate regions: areas with surface |Bz|≥ 300 G, areas of flare brightening seen in SDO Atmospheric Imaging Assembly imagery, and areas with surface |B| ≥ 1000 G and high twist. Time series of the magnetic field parameters were analyzed to investigate the evolution of the coronal field during the solar flare event and discern pre-eruptive signatures. The data shows that areas with |B| ≥ 1000 G and |Tw|≥ 1.5 align well with areas of initial flare brightening during the pre-flare phase and at the beginning of the eruptive phase of the flare, suggesting that measurements of the photospheric magnetic field strength and twist can be used to predict the flare location within an active region if triggered. Additionally, the evolution of seven investigated magnetic field parameters indicated a destabilizing magnetic field structure that could likely erupt

“What if There's Something Wrong with Her?”‐How Biomedical Technologies Contribute to Epistemic Injustice in Healthcare

While there is a steadily growing literature on epistemic injustice in healthcare, there are few discussions of the role that biomedical technologies play in harming patients in their capacity as knowers. Through an analysis of newborn and pediatric genetic and genomic sequencing technologies (GSTs), I argue that biomedical technologies can lead to epistemic injustice through two primary pathways: epistemic capture and value partitioning. I close by discussing the larger ethical and political context of critical analyses of GSTs and their broader implications for just and equitable healthcare delivery

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling.

Aberrant DNA methylation patterns in malignant cells allow insight into tumor evolution and development and can be used for disease classification. Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive (ALK+) and NPM-ALK-negative (ALK-) anaplastic large-cell lymphoma (ALCL). We find that ALK+ and ALK- ALCL share common DNA methylation changes for genes involved in T cell differentiation and immune response, including TCR and CTLA-4, without an ALK-specific impact on tumor DNA methylation in gene promoters. Furthermore, we uncover a close relationship between global ALCL DNA methylation patterns and those in distinct thymic developmental stages and observe tumor-specific DNA hypomethylation in regulatory regions that are enriched for conserved transcription factor binding motifs such as AP1. Our results indicate similarity between ALCL tumor cells and thymic T cell subsets and a direct relationship between ALCL oncogenic signaling and DNA methylation through transcription factor induction and occupancy.G.E. was funded by the Austrian Science Foundation (FWF) (P 27616 and V 102). M.R.H. was supported by a L’Oréal for Women in Science grant. S.D.T. receives funding from Bloodwise (formerly Leukaemia and Lymphoma Research). L.K. has been funded by the FWF (P 26011 and P 29251), as well as the MSCA-ITN-2015-ETN ALKATRAS (No. 675712). D.J.W. is a paid consultant for Zymo Research Corporation.This is the final version of the article. It first appeared from Elsevier (Cell Press) via http://dx.doi.org/10.1016/j.celrep.2016.09.01

Identification of quantitative trait loci influencing skeletal architecture in mice: Emergence of Cdh11 as a primary candidate gene regulating femoral morphology

Bone strength is influenced by many properties intrinsic to bone, including its mass, geometry, and mineralization. To further advance our understanding of the genetic basis of bone strength-related traits, we utilized a large (N=815), moderately (G4) advanced intercross line (AIL) of mice derived from a high-runner selection line (HR) and the C57BL/6J inbred strain. In total, 16 quantitative trait loci (QTL) were identified that affected areal bone mineral density (aBMD) and femoral length and width. Four significant (P<0.05) and one suggestive (P<0.10) QTL were identified for three aBMD measurements: total body, vertebral and femoral. A QTL on Chromosome (Chr.) 3 influenced all three aBMD measures, while the other four QTL were unique to a single measure. A total of 10 significant and one suggestive QTL were identified for femoral length (FL) and two measures of femoral width, anterior-posterior (AP) and medial-lateral (ML). FL QTL were distinct from loci affecting AP and ML width, and of the seven AP QTL, only three affected ML. A QTL on Chr. 8 that explained 7.1% and 4.0% of the variance in AP and ML, respectively, was mapped to a six megabase (Mb) region harboring 12 protein-coding genes. The pattern of haplotype diversity across the QTL region and expression profiles of QTL genes, suggested that of the 12, cadherin 11 (Cdh11) was most likely the causal gene. These findings, when combined with existing data from gene knockouts, identify Cdh11 as a strong candidate gene within which genetic variation may affect bone morphology

The effects of nationality differences and work stressors on work adjustment for foreign nurse aides

<p>Abstract</p> <p>Background</p> <p>The main purpose of this study was to discuss the nationality differences of foreign nurse aides and the effect of work stressors influencing work adjustment. And of helping them adapt to Taiwanese society, we summarized the difficulties that foreign nurse aides face in Taiwan.</p> <p>Methods</p> <p>The subjects included 80 foreign nurse aides from the Philippines, Indonesia, and Vietnam who worked in long-term care facilities in Tao Yuan County. We recruited volunteers at the participating facilities to complete the anonymous questionnaires. The return rate of the questionnaire was 88.75%. The validated instruments of Hershenson's (1981) and Schaefer and Moos (1993) were adopted to measure work stressors and work adjustment, respectively. A forward-backward translation process was used in this study.</p> <p>Results</p> <p>Indonesian foreign nurse aides respect their work, and are better workers than Vietnamese and Filipino nurse aids in many respects, which shows how the nationality of the foreign nurse aides might affect work adjustment. The stress created from patient care tasks influenced the foreign nurse aides' personal relationships at work and also affected their attitude when they performed their tasks. In addition, pressure from their supervisors might have affected their work skills, work habits, personal relationships, self-concepts or work attitudes. Moreover, a heavy workload and improper scheduling might have affected the personal relationships and work attitudes of the foreign nurse aides. It was found that work stressors had a significant correlation with work adjustment.</p> <p>Conclusions</p> <p>The results of the present study indicate that training programs are important factors for work adjustment among foreign nurse aides. Furthermore, celebration and leisure activities could be provided to release them from work stressors. More effort should be put into improving the working environment, namely providing a more supportive and enriching atmosphere. Based on these findings, we have a better understanding of how to assist foreign nurse aides in the future.</p

Finite-Size Effects and Dynamical Scaling in Two-Dimensional Josephson Junction Arrays

In recent years many groups have used Fisher, Fisher, and Huse (FFH) dynamical scaling to investigate and demonstrate details of the superconducting phase transition. Some attention has been focused on two dimensions where the phase transition is of the Kosterlitz-Thouless-Berezinskii (KTB) type. Pierson et al. used FFH dynamical scaling almost exclusively to suggest that the dynamics of the two-dimensional superconducting phase transition may be other than KTB-like. In this work we investigate the ability of scaling behavior by itself to yield useful information on the nature of the transition. We simulate current-voltage (IV) curves for two-dimensional Josephson junction arrays with and without finite-size-induced resistive tails. We find that, for the finite-size effect data, the values of the scaling parameters, specifically the transition temperature and the dynamical scaling exponent z, depend critically on the magnitude of the contribution that the resistive tails make to the IV curves. In effect, the values of the scaling parameters depend on the noise floor of the measuring system.Comment: 24 pages, 8 figures; submitted to Physical Review