15,730 research outputs found
Storage capacity of a constructive learning algorithm
Upper and lower bounds for the typical storage capacity of a constructive
algorithm, the Tilinglike Learning Algorithm for the Parity Machine [M. Biehl
and M. Opper, Phys. Rev. A {\bf 44} 6888 (1991)], are determined in the
asymptotic limit of large training set sizes. The properties of a perceptron
with threshold, learning a training set of patterns having a biased
distribution of targets, needed as an intermediate step in the capacity
calculation, are determined analytically. The lower bound for the capacity,
determined with a cavity method, is proportional to the number of hidden units.
The upper bound, obtained with the hypothesis of replica symmetry, is close to
the one predicted by Mitchinson and Durbin [Biol. Cyber. {\bf 60} 345 (1989)].Comment: 13 pages, 1 figur
Effects of material nonlinearity on the global analysis and stability of stainless steel frames
© 2017 Elsevier Ltd In structural frames, second order effects refer to the internal forces and moments that arise as a result of deformations under load (i.e. geometrical nonlinearity). EN 1993-1-1 states that global second order effects may be neglected if the critical load factor of the frame αcris greater than or equal to 10 for an elastic analysis, or greater than or equal to 15 when a plastic global analysis is used. No specific guidance is provided in EN 1993-1-4 for the design of stainless steel frames, for which the nonlinear stress-strain behaviour of the material will result in greater deformations as the material loses its stiffness. A study of the effects of material nonlinearity on the stability of stainless steel frames is presented herein. A series of different frame geometries and loading conditions are considered. Based on the findings, proposals for the treatment of the influence of material nonlinearity on the global analysis and design of stainless steel frames are presented
Two 2MASS-Selected Young Stellar Clusters: Photometry, Spectroscopy, and the IMF
We present near-infrared J, H, and K_s images and K-band spectroscopy of two
newly discovered stellar clusters at different stages of evolution. Our spectra
suggest the presence of massive YSOs in the heavily embedded cluster in the
star-forming region near radio source G353.4-0.4 and an O5-O6V star in the
cluster near radio source G305+00.2. We determine a K-band luminosity function
(KLF) for both clusters and an initial mass function (IMF) for the cluster near
G305+00.2. The derived IMF slope is -1.5 if the KLF is used to derive the IMF
and is -0.98 if the color-magnitude diagram and spectra are used. The more
reliable CMD-based slope is flatter than the Salpeter value usually found for
stellar clusters. We find that using the KLF alone to derive an IMF is likely
to produce an overly steep slope in stellar clusters subject to variable
extinction.Comment: 16 pages, 18 figures, accepted to A
Absence of anomalous negative lattice-expansion for polycrystalline sample of Tb2Ti2O7
High resolution X-ray powder-diffraction experiments on a well-characterized
polycrystalline sample of the spin liquid Tb2Ti2O7 reveal that it shows normal
positive thermal-expansion above 4 K, which does not agree with the intriguing
anomalous negative thermal-expansion due to a magneto-elastic coupling reported
for a single crystal sample below 20 K. We also performed a Rietveld profile
refinement of a powder-diffraction pattern taken at a room temperature, and
confirmed that it is consistent with the fully ordered cubic pyrochlore
structure.Comment: 2 pages, 3 figure
Large Deviation Property of Free Energy in p-Body Sherrington-Kirkpatrick Model
Cumulant generating function phi(n) and rate function Sigma(f) of the free
energy is evaluated in p-body Sherrington-Kirkpatrick model by using the
replica method with the replica number n finite. From a perturbational
argument, we show that the cumulant generating function is constant in the
vicinity of n = 0. On the other hand, with the help of two analytic properties
of phi(n), the behavior of phi(n) is derived again. However this is also shown
to be broken at a finite value of n, which gives a characteristic value in the
rate function near the thermodynamic value of the free energy. Through the
continuation of phi(n) as a function of n, we find out a way to derive the 1RSB
solution at least in this model, which is to fix the RS solution to be a
monotone increasing function.Comment: 7 pages, 5 figures. accepted for publication in J.Phs.Soc.Jp
Language attitudes and use in a transplanted setting: Greek Cypriots in London
In this paper we explore language attitudes and use in the Greek Cypriot community in London, England. Our study is based on an earlier survey carried out in Nicosia, Cyprus and we compare attitudes to language and reported language use in the two communities. We thereby highlight the significance of sociolinguistic variables on similar groups of speakers. We further extend our investigation to include codeswitching practices in the London community.
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Analysis of language attitudes and use within the Greek-Cypriot population of London, and comparisons with findings in Nicosia, reflect symbolic forces operating in the two contexts. Despite obvious differences between the two communities, (most obviously the official languages and distinct cultural backgrounds of the two nations), the Greek Cypriot Dialect continues to play an active role in both. English is however the ‘default choice‘ for young Cypriots in the UK and Standard Modern Greek occupies a much more limited role than in Cyprus. It is argued that differences in language attitudes and use can be interpreted in light of different market forces operating in the nation (i.e. Cyprus) and the Diaspora (i.e. UK)
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Analysis of three epoetin alpha products by LC and LC-MS indicates differences in glycosylation critical quality attributes, including sialic acid content
Erythropoietin (EPO) is one of the main therapeutics used to treat anaemic patients, greatly improving their quality of life. In this study, biosimilars Binocrit and a development product, called here CIGB-EPO, were compared to the originator product, Eprex. All three are epoetin alpha products, reputed to have similar glycosylation profiles. The quality, safety and efficacy of this biotherapeutic depend on the following glycosylation critical quality attributes (GCQAs): sialylation, N-glycolyl-neuraminic acid (Neu5Gc) content, branching, N-acetyl-lactosamine (LacNAc) extensions and O-acetylation pattern. Reverse-phase ultra high pressure liquid chromatography (RP-UHPLC) analysis of acid-released, 1,2-diamino-4,5-methylenedioxybenzene (DMB) labelled sialic acid derivatives and hydrophilic interaction liquid chromatography (HILIC) in combination with mass spectrometry (HILIC-UHPLC-MS) of procainamide (PROC) labelled N-glycans were the analytical tools used. An automated method for enzymatic release and PROC labelling was applied for the first time to the erythropoiesis stimulating agent (ESA) products, which facilitated novel, in-depth characterisation, and allowed identification of precise structural features including the location of O-acetyl groups on sialic acid (SA) moie-ties. Samples were digested by a sialate-O-acetylesterase (NanS) to confirm the presence of O-acetyl groups. It was found that Eprex contained the greatest relative abundance of O-acetylated derivatives, Binocrit expressed the least Neu5Gc, and CIGB-EPO showed the greatest variety of high-mannose-phosphate structures. The sialylation and LacNAc extension patterns of the three ESAs were similar, with a maximum of four N-acetyl-neuraminic acid (Neu5Ac) moieties detected per glycan. Such differences in SA derivatisation, particularly O-acetylation, could have consequences for the quality and safety of a biotherapeutic, as well as its efficacy
Symmetries of Differential Equations via Cartan's Method of Equivalence
We formulate a method of computing invariant 1-forms and structure equations
of symmetry pseudo-groups of differential equations based on Cartan's method of
equivalence and the moving coframe method introduced by Fels and Olver. Our
apparoach does not require a preliminary computation of infinitesimal defining
systems, their analysis and integration, and uses differentiation and linear
algebra operations only. Examples of its applications are given.Comment: 15 pages, LaTeX 2.0
Galaxy number counts- IV. surveying the Herschel deep field in the near-infrared
(abridged) We present results from two new near-infrared imaging surveys. One
covers 47.2 arcmin^2 to K(3\sigma)<20 whilst a second, deeper survey covers a
sub-area of 1.8 arcmin^2 to K(3\sigma)<22.75. Over the entire area we have
extremely deep UBRI photometry. Our K- counts are consistent with the
predictions of non-evolving models with 0 < q0 <0.5. The K-selected (B-K)
galaxy colour distributions move sharply bluewards fainter than K~20 and at at
brighter magnitudes (K<20) our observed colour distributions indicate a
deficiency of red, early-type galaxies at z~1 in comparison with passively
evolving models. This implies either a pure luminosity evolution (PLE) model
with a low level of continuing star-formation following an an initial burst, or
dynamical merging. At fainter magnitudes, the continuing bluewards trend
observed in (B-K) can be explained purely in terms of passively evolving PLE
models. Our observed numbers of (I-K)>4 galaxies at K<20 exhibit the same
deficiency, suggesting that at least part of the larger deficit observed in
(B-K) at K<20 may be due to star-formation rather than dynamical merging.
Finally, as we and others have noted, the number-redshift distribution at
18<K<19 of recent, deep K- selected redshift surveys is well fitted by
non-evolving models; passively evolving models with a Salpeter or Scalo initial
mass functions overpredict the numbers of galaxies with z>1. Dynamical merging
is one possible solution to reduce the numbers of these galaxies but a
dwarf-dominated IMF for early-type galaxies could offer an alternative
explanation; we show that this model reproduces both the optical-infrared
colour distributions and the K- band galaxy counts.Comment: 15 pages, 9 figures, revised version, requires astrobib.sty,
mn-abs.sty, submitted to MNRA
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