519 research outputs found
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Dust Around R Coronae Borealis Stars. I. Spitzer/Infrared Spectrograph Observations
Spitzer/infrared spectrograph (IRS) spectra from 5 to 37 mu m for a complete sample of 31 R Coronae Borealis stars (RCBs) are presented. These spectra are combined with optical and near-infrared photometry of each RCB at maximum light to compile a spectral energy distribution (SED). The SEDs are fitted with blackbody flux distributions and estimates are made of the ratio of the infrared flux from circumstellar dust to the flux emitted by the star. Comparisons for 29 of the 31 stars are made with the Infrared Astronomical Satellite (IRAS) fluxes from three decades earlier: Spitzer and IRAS fluxes at 12 mu m and 25 mu m are essentially equal for all but a minority of the sample. For this minority, the IRAS to Spitzer flux ratio exceeds a factor of three. The outliers are suggested to be stars where formation of a dust cloud or dust puff is a rare event. A single puff ejected prior to the IRAS observations may have been reobserved by Spitzer as a cooler puff at a greater distance from the RCB. RCBs which experience more frequent optical declines have, in general, a circumstellar environment containing puffs subtending a larger solid angle at the star and a quasi-constant infrared flux. Yet, the estimated subtended solid angles and the blackbody temperatures of the dust show a systematic evolution to lower solid angles and cooler temperatures in the interval between IRAS and Spitzer. Dust emission by these RCBs and those in the LMC is similar in terms of total 24 mu m luminosity and [8.0]-[24.0] color index.Spanish Ministry of Science and Innovation (MICINN) AYA-2007-64748NASA GO 50212, 1407Robert A. Welch Foundation of Houston, Texas F-634McDonald Observator
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Cno Abundances Of Hydrogen-Deficient Carbon And R Coronae Borealis Stars: A View Of The Nucleosynthesis In A White Dwarf Merger
We present high-resolution (R similar to 50,000) observations of near-IR transitions of CO and CN of the five known hydrogen-deficient carbon (HdC) stars and four R Coronae Borealis (RCB) stars. We perform an abundance analysis of these stars by using spectrum synthesis and state-of-the-art MARCS model atmospheres for cool hydrogen-deficient stars. Our analysis confirms reports by Clayton and colleagues that those HdC stars exhibiting CO lines in their spectrum and the cool RCB star SAps are strongly enriched in (18)O(with (16)O/(18)Oratios ranging from 0.3 to 16). Nitrogen and carbon are in the form of (14)N and (12)C, respectively. Elemental abundances for CNO are obtained from C I, Ci2, CN, and CO lines. Difficulties in deriving the carbon abundance are discussed. Abundances of Na from Na I lines and S from S I lines are obtained. Elemental and isotopic CNO abundances suggest that HdC and RCB stars may be related objects, and that they probably formed from a merger of an He white dwarf with a C-O white dwarf.Robert A. Welch Foundation of Houston, TexasSwedish Research CouncilGS-2006A-C-13GS-2007A-DD-1McDonald Observator
CLEAR EVIDENCE FOR THE PRESENCE OF SECOND-GENERATION ASYMPTOTIC GIANT BRANCH STARS IN METAL-POOR GALACTIC GLOBULAR CLUSTERS
Galactic globular clusters (GCs) are known to host multiple stellar populations: a first generation (FG) with a
chemical pattern typical of halo field stars and a second generation (SG) enriched in Na and Al and depleted in O
and Mg. Both stellar generations are found at different evolutionary stages (e.g., the main-sequence turnoff, the
subgiant branch, and the red giant branch (RGB)). The non detection of SG asymptotic giant branch (AGB) stars in
several metal-poor ([Fe/H] < â1) GCs suggests that not all SG stars ascend the AGB phase, and that failed AGB
stars may be very common in metal-poor GCs. This observation represents a serious problem for stellar evolution
and GC formation/evolution theories. We report fourteen SG-AGB stars in four metal-poor GCs (M13, M5, M3,
and M2) with different observational properties: horizontal branch (HB) morphology, metallicity, and age. By
combining the H-band Al abundances obtained by the Apache Point Observatory Galactic Evolution Experiment
survey with ground-based optical photometry, we identify SG Al-rich AGB stars in these four GCs and show that
Al-rich RGB/AGB GC stars should be Na-rich. Our observations provide strong support for present, standard
stellar models, i.e., without including a strong mass-loss efficiency, for low-mass HB stars. In fact, current
empirical evidence is in agreement with the predicted distribution of FG and and SG stars during the He-burning
stages based on these standard stellar models
Spitzer Infrared Spectrograph Observations of Magellanic Cloud Planetary Nebulae: the nature of dust in low metallicity circumstellar ejecta
We present 5 - 40 micron spectroscopy of 41 planetary nebulae (PNe) in the
Magellanic Clouds, observed with the Infrared Spectrograph on board the Spitzer
Space Telescope. The spectra show the presence of a combination of nebular
emission lines and solid-state features from dust, superimposed on the thermal
IR continuum.
By analyzing the 25 LMC and 16 SMC PNe in our sample we found that the IR
spectra of 14 LMC and 4 SMC PNe are dominated by nebular emission lines, while
the other spectra show solid-state features. We observed that the solid-state
features are compatible with carbon-rich dust grains (SiC, polycyclic aromatic
hydrocarbons (PAHs), etc.) in most cases, except in three PNe showing
oxygen-rich dust features. The frequency of carbonaceous dust features is
generally higher in LMC than in SMC PNe.
The spectral analysis allowed the correlations of the dust characteristics
with the gas composition and morphology, and the properties of the central
stars. We found that: 1) all PNe with carbonaceous dust features have C/O>1,
none of these being bipolar or otherwise highly asymmetric; 2) all PNe with
oxygen-rich dust features have C/O<1, with probable high mass progenitors if
derived from single-star evolution (these PNe are either bipolar or highly
asymmetric); 3) the dust temperature tracks the nebular and stellar evolution;
and 4) the dust production efficiency depends on metallicity, with low
metallicity environments not favoring dust production.Comment: The Astrophysical Journal, in pres
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Mapping The Interstellar Medium With Near-Infrared Diffuse Interstellar Bands
We map the distribution and properties of the Milky Way's interstellar medium as traced by diffuse interstellar bands (DIBs) detected in near-infrared stellar spectra from the SDSS-III/APOGEE survey. Focusing exclusively on the strongest DIB in the H band, at lambda similar to 1.527 mu m, we present a projected map of the DIB absorption field in the Galactic plane, using a set of about 60,000 sightlines that reach up to 15 kpc from the Sun and probe up to 30 mag of visual extinction. The strength of this DIB is linearly correlated with dust reddening over three orders of magnitude in both DIB equivalent width (Wpm) and extinction, with a power law index of 1.01 +/- 0.01, a mean relationship of W-DIB/A(v) = 0.1 angstrom mag(-1) and a dispersion of similar to 0.05 angstrom mag(-1) at extinctions characteristic of the Galactic midplane. These properties establish this DIB as a powerful, independent probe of dust extinction over a wide range of Av values. The subset of about 14,000 robustly detected DIB features have a W-DIB distribution that follows an exponential trend. We empirically determine the intrinsic rest wavelength of this transition to be lambda(0) = 15 272.42 angstrom and use it to calculate absolute radial velocities of the carrier, which display the kinematical signature of the rotating Galactic disk. We probe the DIB carrier distribution in three dimensions and show that it can be characterized by an exponential disk model with a scale height of about 100 pc and a scale length of about 5 kpc. Finally, we show that the DIB distribution also traces large-scale Galactic structures, including the Galactic long bar and the warp of the outer disk.NSF Astronomy & Astrophysics Postdoctoral Fellowship AST-1203017NSF AST-1109665Alfred P. Sloan FoundationNational Science FoundationU.S. Department of Energy Office of ScienceUniversity of ArizonaBrazilian Participation GroupBrookhaven National LaboratoryUniversity of CambridgeCarnegie Mellon UniversityUniversity of FloridaFrench Participation GroupGerman Participation GroupHarvard UniversityInstituto de Astrofisica de CanariasMichigan State/Notre Dame/JINA Participation GroupJohns Hopkins UniversityLawrence Berkeley National LaboratoryMax Planck Institute for AstrophysicsMax Planck Institute for Extraterrestrial PhysicsNew Mexico State UniversityNew York UniversityOhio State UniversityPennsylvania State UniversityUniversity of PortsmouthPrinceton UniversitySpanish Participation GroupUniversity of TokyoUniversity of UtahVanderbilt UniversityUniversity of VirginiaUniversity of WashingtonYale UniversitySpanish Ministry of Economy and Competitiveness AYA-2011-27754McDonald Observator
Chemical abundance gradients from open clusters in the Milky Way disk: results from the APOGEE survey
Metallicity gradients provide strong constraints for understanding the
chemical evolution of the Galaxy. We report on radial abundance gradients of
Fe, Ni, Ca, Si, and Mg obtained from a sample of 304 red-giant members of 29
disk open clusters, mostly concentrated at galactocentric distances between ~8
- 15 kpc, but including two open clusters in the outer disk. The observations
are from the APOGEE survey. The chemical abundances were derived automatically
by the ASPCAP pipeline and these are part of the SDSS III Data Release 12. The
gradients, obtained from least squares fits to the data, are relatively flat,
with slopes ranging from -0.026 to -0.033 dex/kpc for the alpha-elements [O/H],
[Ca/H], [Si/H] and [Mg/H] and -0.035 dex/kpc and -0.040 dex/kpc for [Fe/H] and
[Ni/H], respectively. Our results are not at odds with the possibility that
metallicity ([Fe/H]) gradients are steeper in the inner disk (R_GC ~7 - 12 kpc)
and flatter towards the outer disk. The open cluster sample studied spans a
significant range in age. When breaking the sample into age bins, there is some
indication that the younger open cluster population in our sample (log age <
8.7) has a flatter metallicity gradient when compared with the gradients
obtained from older open clusters.Comment: 4 pages, 3 figures, To appear in Astronomische Nachrichten, special
issue "Reconstruction the Milky Way's History: Spectroscopic surveys,
Asteroseismology and Chemo-dynamical models", Guest Editors C. Chiappini, J.
Montalb\'an, and M. Steffen, AN 2016 (in press)
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodiumâglucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with reninâangiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
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