IoMT-Driven eHealth: A Technological Innovation Proposal Based on Smart Speakers

Internet of Medical Things (IoMT) is a technological concept applied in healthcare contexts to achieve the digital interconnection of everyday objects with the Internet in order to make life easier for people. IoMT can help monitor, inform and notify not only caregivers, but provide healthcare providers with actual data to identify issues before they become critical or to allow for earlier invention. In this sense, this paper is contextualized in Assisted Repro duction Treatment (ART) processes to reduce the number of hospital visits, reduce healthcare costs and improve patientcare, as well as the productivity of the healthcare professional. So, we present an IoMT-based technological pro posal to manage and control the prescription of pharmacological treatments to patients who are carried out ART processes. In this context, we propose the integration of iMEDEA (modular system specialized in the management of electronic clinical records for ART unit) and smart speaker devices (specifically, Amazon’s Alexa), as well as the validation of our proposal in the real envi ronment offered by Inebir clinicMinisterio de Economía y Competitividad TIN2016-76956-C3-2-R (POLOLAS)Junta de Andalucía AT17-5904-US

Finite Element Simulation of the Deformation of a Cell Driven by Creeping Flow

The purpose of this work is to calculate the deformation undergone by a cell in function of its nucleus size and mechanical properties. The cell immersed in a fluid go through a variable section channel and it is deformed by fluid forces.Cell deformation into the channel causes changes at the fluid velocity profile. This fluid configuration change results in diferent normal and viscous forces around the cell. Due to strong correlation between cell deformation and fluid velocity profile, a fluidsolid interacción (FSI) is required

New objects in old structures: The Iron Age hoard of the Palacio III megalithic funerary complex (Almadén de la Plata, Seville, Spain)

Cultural contact, exchange and interaction feature high in the list of challenging topics of current research on European Prehistory. Not far off is the issue of the changing role of monuments in the making and maintaining of key cultural devices such as memory and identity. Addressing both these highly-debated issues from a science-based perspective, in this paper we look at an unusual case study set in southern Iberia and illustrate how these archaeological questions can benefit from robust materials-science approaches.We present the contextual, morphological and analytical study of an exceptional Early Iron Age hoard composed of a number of different (and mostly exotic) materials such as amber, quartz, silver and ceramic. This hoard, found under the fallen orthostat of a megalithic structure built at least 2000 years earlier, throws new light on long-distance exchange networks and the effect they could have had on the cultural identities and social relations of local Iberian Early Iron Age communities. Moreover, the archaeometric study reveals how diverse and distant the sources of these item are (Northern Europe to Eastern and Western Mediterranean raw materials, as well as local and eastern technologies), therefore raising questions concerning the social mechanisms used to establish change and resistance in contexts of colonial encounter

Biofilm formation in total hip arthroplasty: Prevention and treatment

Biomaterials science is a very active area of research, which has allowed the successful use of implants in the orthopaedic field for over a century. However, implant infection remains a clinical concern as it is associated with extensive patient morbidity and a high economic burden, which is predicted to increase due to an ageing population. Bacteria are able to adhere, colonise and develop into biofilms on the surface of biomaterials making associated infections physiologically different to other post-surgical infections. Unfortunately, biofilms exert increased protection from the host immune system and an increased resistance to antibiotic therapy in comparison to their planktonic counterparts. The aim of this review is to assess the current knowledge on treatments, pathogenesis and the prevention of infections associated with orthopaedic implants, with a focus on total hip arthroplasty

On First-Passage Times and Sojourn Times in Finite QBD Processes and Their Applications in Epidemics

In this paper, we revisit level-dependent quasi-birth-death processes with finitely many possible values of the level and phase variables by complementing the work of Gaver, Jacobs, and Latouche (Adv. Appl. Probab. 1984), where the emphasis is upon obtaining numerical methods for evaluating stationary probabilities and moments of first-passage times to higher and lower levels. We provide a matrix-analytic scheme for numerically computing hitting probabilities, the number of upcrossings, sojourn time analysis, and the random area under the level trajectory. Our algorithmic solution is inspired from Gaussian elimination, which is applicable in all our descriptors since the underlying rate matrices have a block-structured form. Using the results obtained, numerical examples are given in the context of varicella-zoster virus infections

Low-Degree High-Frequency p and g Modes in the Solar Core

Solar gravity (g) modes propagate within the radiative part of the solar interior and are highly sensitive to the physical conditions of the solar core. They would represent the best tool to infer the structure and dynamics of the radiative interior, in particular the core, if they were properly detected and characterized. Although individual rotational splittings for g modes have not yet been calculated, we have to understand the effect of these modes, and also low-degree high-frequency p modes, on the inversion of the solar rotation rate between 0.1 and 0.2 Rs. In this work, we follow the methodology developed in Mathur et al. (2008) and Garcia et al. (2008), adding g modes and low-degree high-frequency p modes to artificial inversion data sets, in order to study how they convey information on the solar core rotation.Comment: To appear in "Magnetic Coupling between the Interior and the Atmosphere of the Sun", eds. S.S. Hasan and R.J. Rutten, Astrophysics and Space Science Proceedings, Springer-Verlag, Heidelberg, Berlin, 200

Bacteriocin Producing Lactobacilli Strains as a Biological Strategy to Control Listerial Growthc

Listeria monocytogenes causes listeriosis in humans and animals, and is predominantly transmitted by ingestion of contaminated food. Its severity and high mortality rate make listeriosis a relevant foodborne disease. Currently, biological strategies using probiotic lactobacilli to prevent and control infectious diseases are being globally investigated. The biocontrol exerted by certain Lactobacillus spp. is mainly due to the production of a variety of antimicrobial substances. The aims of this work were (1) to investigate the presence of Listeria spp. in raw cow milk and (2) to determine the inhibitory activity of bacteriocin-like inhibitory substances (BLIS-es) produced by Lactobacillus fermentum L23 and Lactobacillus rhamnosus L60 on L. monocytogenes and other listerial species isolated from food and clinical samples. The presence of Listeria spp. in raw milk was evaluated in 814 samples from 238 cows. The listerial prevalence in cattle was 0.84% and the isolates were identified as L. innocua (LI1) and L. welshimeri (LW1). A total of 29 listerial strains were used as indicator microorganisms to evaluate the antimicrobial activity of BLIS-es L23 and L60. Bioactive metabolites produced by these lactobacilli strains were able to inhibit the listerial growth. This biological activity was mainly attributed to the BLIS-es L23 and L60 which, even at low concentration, were active on 100% of listerial strains. This study reveals a strong potential for the biotechnological use of these bacteriocin producing lactobacilli as a biostrategy against Listeria spp

Los programas de case management. Conceptos básicos y aplicabilidad.

Se revisa el origen, motivación y definición de los programas de case management desarrollados, sobre todo, en los Estados Unidos de América. Se enumeran los diversos modelos de estos programas, los principios en que diversos autores lo fundamentan y las actividades que en ellos se desarrollan, así como los aspectos de personal que conllevan. Se discuten diversas apreciaciones sobre su eficacia y la posibilidad de su puesta en marcha en un contexto diferente al que los originó, en Europa del sur

ESTUDIO DE LA ADECUACIÓN DEL GRADO DE ENFERMERÍA DE LA UNIVERSIDAD DE VALLADOLID A LAS NECESIDADES SOCIOSANITARIAS DE LA POBLACIÓN Y FORMULACIÓN DE PROPUESTAS DE FORMACIÓN

Society, as a dynamic entity, undergoes changes at the cultural, social, economic, and political level. Therefore health care must adapt to them, meeting the new needs that may arise. The objective of this research is to analyze the health and social needs presented by the population today and to determine whether or not to include new subjects in a future Nursing Degree from the University of Valladolid, Spain to respond to these. Key aspects that make up the health and social context will be analyzed. This way, the demographic profile of Spanish society; an aging population, caring for dependent persons, the state of health of the population, domestic violence, voluntary interruption of pregnancy and sexual and reproductive health, as well as cultural diversity of Spain and the immigration process, will be studied. Additionally, nurse orders, recently adopted competencies, and general study skills that a nurse must have will be analyzedLa sociedad, como ente dinámico, sufre variaciones a nivel cultural, social, económico o político y la atención sanitaria debe adaptarse a éstas, satisfaciendo las nuevas necesidades que van surgiendo. El objetivo de la investigación es analizar las necesidades sociosanitarias que presenta la población en la actualidad y determinar si es necesario incluir nuevos contenidos curriculares en el futuro Grado de Enfermería de la Universidad de Valladolid, para dar respuesta a las mismas. Se analizarán los aspectos claves que conforman el contexto sociosanitario. Así, se estudiará el perfil demográfico de la sociedad española, el progresivo envejecimiento poblacional, la atención a las personas dependientes, el estado de salud de la población, la violencia de género, la interrupción voluntaria del embarazo y la salud sexual y reproductiva, la diversidad cultural que presenta nuestro país y el proceso de inmigración. También se analizará la prescripción enfermera, competencia aprobada recientemente, y se estudiarán las competencias generales que debe adquirir un profesional de enfermería