Application of the contents of a Master on Teaching in Higher Education to the planning of a subject adapted to EHEA

La formación y profesionalización de las tareas docentes es una de las respuestas a las exigencias de calidad y excelencia docentes. Ser un profesional docente eficiente y eficaz requiere la adquisición de unas competencias que permitan ejercer su función adecuadamente. La planificación de una nueva asignatura en el marco del Espacio Europeo de Educación Superior (EEES) supone un reto que hay que asumir para realizar una docencia de calidad. La puesta en marcha de una nueva asignatura es una gran oportunidad para reflexionar individualmente y con otros profesores sobre la práctica docente y para profundizar en procesos de innovación en metodología docente, en los recursos a utilizar, en los sistemas de evaluación, en la definición de objetivos y en la selección de contenidos. El objetivo del trabajo realizado consistió en aplicar los conocimientos adquiridos en el Máster en “Docencia Universitaria para profesorado novel” a la elaboración del plan docente de la asignatura “Farmacia Galénica I” que se impartirá en el sexto semestre del Grado de Farmacia en la Universidad de Barcelona. El plan docente que se ha elaborado ha tenido como referente las competencias de la titulación y los contenidos se han delimitado en relación a los objetivos formativos de la asignatura. Las estrategias metodológicas propuestas y la evaluación del proceso de aprendizaje se han adaptado a la docencia de grupos muy numerosos (80-100 alumnos), intentando favorecer la autonomía del alumnado.The training and professionalization of the educational tasks is one of the answers to the educational requirements of quality and excellence. To be an efficient and effective professional need the acquisition of a few competences that allows exercising his function adequately. The planning of a new subject in the frame of the European Higher Education Area (EHEA) supposes a challenge that it is necessary to take up to manage a high quality teaching. The development of a new subject is a great opportunity to think individually and with other colleagues on the educational practice and to penetrate into processes of innovation into educational methodology, in the higher education resources, in the evaluation, in the definition of aims and in the selection of contents. The aim of the present work consisted of applying the knowledge acquired in the Master in "Higher Education Teaching for young teachers" to the elaboration of the learning plan of the subject "Farmacia Galénica I" that will be given in the sixth semester of the Degree of Pharmacy in the University of Barcelona. The learning plan that has been elaborated has taken the competences of the degree in Pharmacy as a model and the contents have been delimited in relation to the formative aims of the subject. The methodological strategies and the evaluation of the learning process have been adapted to the teaching of groups with 80-100 students, trying to help the autonomy of the student

Ethylcellulose nanoparticles as a new “in vitro” transfection tool for antisense oligonucleotide delivery

Oil-in-water nano-emulsions have been obtained in the HEPES 20 mM buffer solution / [Alkylamidoammonium:Kolliphor EL = 1:1] / [6 weight% ethylcellulose in ethyl acetate] system over a wide oil-to-surfactant range and above 35 weight% aqueous component at 25 °C. The nano-emulsion with an oil-to-surfactant ratio of 70/30 and 95 weight% aqueous component was used for nanoparticles preparation. These nanoparticles (mean diameter around 90 nm and zeta potential of +22 mV) were non-toxic to HeLa cells up to a concentration of 3 mM of cationic species. Successful complexation with an antisense phosphorothioate oligonucleotide targeting Renilla luciferase mRNA was achieved at cationic/anionic charge ratios above 16, as confirmed by zeta potential measurements and an electrophoretic mobility shift assay, provided that no Fetal Bovine Serum is present in the cell culture medium. Importantly, Renilla luciferase gene inhibition shows an optimum efficiency (40%) for the cationic/anionic ratio 28, which makes these complexes promising for “in vitro” cell transfection.The DLS, zeta potential and Turbiscan analyses have been performed at the Nanostructured Liquid Characterization Unit, located at the Institute of Advanced Chemistry of Catalonia (IQAC), belonging to the Spanish National Research Council (CSIC) and affiliated to the NANBIOSIS ICTS of the Biomedical Networking Center (CIBER-BBN). CIBER-BBN is an initiative funded by the VI National R&D&I Plan 2008-2011. Financial support from MINECO (grant CTQ2017-84998-P (AEI/FEDER,UE) and Generalitat de Catalunya (grant 2009SGR-961) is acknowledged. S.L. is grateful to CIBER-BBN for a research scholarship. Colorcon and Bonderalia S.A./Quimivita S.A. and BASF are gratefully acknowledged for the gift of ethylcellulose, ricinoleamidopropyltrimonium methosulfate and Kolliphor EL respectively.Peer reviewe

CONTACT LENSES FUNCTIONALIZED WITH ANTIMICROBIAL PEPTIDES FOR THE PREVENTION OF CORNEAL INFECTIONS

One of the most common problems related to contact lenses is associated with microbial infection