La intervención del sector fiduciario en la ley anticorrupción 1474 de 2011

Este documento analiza el impacto que tiene el Sector Fiduciario al recibir los dineros por contratos de anticipos, sin tener un adecuado procedimiento que facilite la eficacia y eficiencia en el manejo de los recursos públicos. Así mismo, este documento sirve de apoyo para mejorar el desarrollo en la contratación estatal para los anticipos de Fiducia.This document analyzes the impact of the Fiduciary Sector, to receive monies in advance contracts without proper procedure to facilitate the effective and efficient management of public resources. Also, this document provides support to improve development in government contracting for advances Fiducia

Desarrollo de un laboratorio virtual para la medida de ciclos indicados de un motor alternativo policombustible de encendido provocado

Se ha desarrollado un laboratorio virtual para la medida de ciclos indicados en un motor alternativo policombustible de encendido provocado. El laboratorio virtual desarrollado permite por una parte simular y obtener el ciclo indicado de un motor alternativo de cuatro tiempos, pudiendo modificar los parámetros más importantes de operación (régimen de giro, presiones de admisión y escape, temperaturas, etc.) y de diseño (parámetros geométricos del motor). Por otra parte, el laboratorio virtual permite simular el ensayo del motor en banco de pruebas y la medida del ciclo indicado. Los modelos matemáticos necesarios se han escrito en lenguaje Fortran, y estos interaccionan con un interfaz gráfico de usuario (GUI) programado en VEE®. El laboratorio virtual puede implementarse en una plataforma virtual de enseñanza de manera que los alumnos puedan tener acceso al sistema desde cualquier ordenador, en cualquier momento y desde cualquier lugar

Electrochemical study of platinum deposited by electron beam evaporation for application as fuel cell electrodes

Platinum is the most used catalyst in electrodes for fuel cells due to its high catalytic activity. Polymer electrolyte and direct methanol fuel cells usually include Pt as catalyst in their electrodes. In order to diminish the cost of such electrodes, different Pt deposition methods that permit lowering the metal load whilst maintaining their electroactivity, are being investigated. In this work, the behaviour of electron beam Pt (e-beam Pt) deposited electrodes for fuel cells is studied. Three different Pt loadings have been investigated. The electrochemical behaviour by cyclic voltammetry in H2SO4, HClO4 and in HClO4+MeOH before and after the Pt deposition on carbon cloth has been analysed. The Pt improves the electrochemical properties of the carbon support used. The electrochemical performance of e-beam Pt deposited electrodes was finally studied in a single direct methanol fuel cell (DMFC) and the obtained results indicate that this is a promising and adequate method to prepare fuel cell electrodes

Electrochemical study of platinum deposited by electron beam evaporation for application as fuel cell electrodes

Platinum is the most used catalyst in electrodes for fuel cells due to its high catalytic activity. Polymer electrolyte and direct methanol fuel cells usually include Pt as catalyst in their electrodes. In order to diminish the cost of such electrodes, different Pt deposition methods that permit lowering the metal load whilst maintaining their electroactivity, are being investigated. In this work, the behaviour of electron beam Pt (e-beam Pt) deposited electrodes for fuel cells is studied. Three different Pt loadings have been investigated. The electrochemical behaviour by cyclic voltammetry in H2SO4, HClO4 and in HClO4+MeOH before and after the Pt deposition on carbon cloth has been analysed. The Pt improves the electrochemical properties of the carbon support used. The electrochemical performance of e-beam Pt deposited electrodes was finally studied in a single direct methanol fuel cell (DMFC) and the obtained results indicate that this is a promising and adequate method to prepare fuel cell electrodes

Impact of Stem Cell Genes in Gastric Cancer

Gastric cancer remains one of the leading causes of global cancer mortality. It has been shown that gastric cancer may originate from adult gastric stem cells and that it contains a subpopulation of cancer cells with stem cell characteristics, which are linked to Helicobacter pylori infection, therapy resistance and metastasis. Thus, the identification of transcription factors and related signal transduction pathways that regulate stem cell maintenance and lineage allocation is attractive from a clinical standpoint in that it may provide targets for novel cell- or drug-based therapies. This chapter summarizes the role of several important stem cell factors in gastric cancer biology

Diseño de una instalación para ensayo de pilas de combustible en condiciones atmosféricas de vuelo de un avión no tripulado

Después de estudiar la idoneidad de las pilas de combustible tipo PEM de hidrógeno y DMFC de metanol directo para su utilización en sistemas propulsivos de aeronaves no tripuladas (UAV), se procedió a simular sus respectivas curvas de polarización en condiciones de vuelo. Es importante estudiar cómo afecta al rendimiento de las pilas de combustible la variación de las condiciones atmosféricas durante el vuelo de un UAV, dado que la mayor parte de los sistemas comerciales están concebidos para su uso en tierra. Por tanto, es de interés la validación de esos modelos de simulación a partir de datos experimentales. Para ello, se presenta en este trabajo el diseño de un banco experimental climatizado de pilas de combustible, en el que poder variar magnitudes como la presión atmosférica, la temperatura o la humedad relativa. Permitirá elegir los casos simulados de mayor interés típicos de la envolvente de vuelo de distintos tipos de UAV en función de las características de la instalación. El banco consiste en una cámara climática estanca y aislada térmicamente a la que van conectados un circuito de refrigeración con intercambiador de calor y una bomba de vacío. En una segunda fase se incluirá un evaporador para el estudio de la humedad relativa. Se elige control PID mediante sonda PT100 y sensores de presión y humedad. El diseño permite condiciones suficientes de estabilidad geométrica y temporal en el interior de la cámara como para estudiar los casos elegidos. Estudios previos similares, se centran en pilas de combustible alimentadas con hidrógeno. En este caso se pueden estudiar también pilas de combustible de metanol, para la que ya existen ejemplos de UAV

Perspectives on the design and use of direct alcohol fuel cells fed by alcohol blends

The fast-growing power demand by portable electronic devices has promoted the increase of global production of portable PEM fuel cell, a quarter of them consist of direct methanol fuel cell (DMFC) units. These present the advantage of being fuelled directly with a liquid fuel, as well as direct ethanol fuel cells (DEFC) do

Comportamiento electroquímico y en pila de combustible de cátodos fabricados mediante evaporacion electrónica de Pt frente a electrodos comerciales

(SPA) Con el objetivo de disminuir el coste de los electrodos utilizados en las pilas de combustible de membrana polimérica se ha llevado a cabo un estudio de la influencia sobre la respuesta electroquímica y en ensayos en monocelda de pila de combustible de alcohol directo, de la deposición por evaporación electrónica de platino sobre tela de carbón. Se han estudiado en las mismas condiciones dos electrodos comerciales con distinta carga de catalizador y dos electrodos preparados por evaporación electrónica de platino. Se encuentra que la evaporación electrónica de platino sobre tela de carbón ahorra carga de catalizador, aumenta la superficie electroactiva y permite alcanzar rendimientos comparables a los de los electrodos comerciales, mejorando mucho la potencia obtenida por unidad de masa de material catalítico. (ENG) In order to diminish the cost of the electrodes used in polymer membrane fuel cells a study of the influence on the electrochemical response and essays in a single direct methanol fuel cell of the deposition by electronic evaporation of Platinum on carbon cloth has been carried out. Two commercial electrodes with different catalyst loading and two electrodes prepared by electronic evaporation of Platinum have been studied in the same conditions. It can be concluded that electronic evaporation of Platinum on carbon cloth saves catalyst load, increases the electroactive surface area and reaches fuel cell performances comparable with those obtained using commercial electrodes, improving clearly the power obtained per unit mass of catalytic material

Exposure to bisphenol-a during pregnancy partially mimics the effects of a high-fat diet altering glucose homeostasis and gene expression in adult male mice

sem informaçãoBisphenol-A (BPA) is one of the most widespread EDCs used as a base compound in the manufacture of polycarbonate plastics. The aim of our research has been to study how the exposure to BPA during pregnancy affects weight, glucose homeostasis, pancreatic β-cell function and gene expression in the major peripheral organs that control energy flux: white adipose tissue (WAT), the liver and skeletal muscle, in male offspring 17 and 28 weeks old. Pregnant mice were treated with a subcutaneous injection of 10 µg/kg/day of BPA or a vehicle from day 9 to 16 of pregnancy. One month old offspring were divided into four different groups: vehicle treated mice that ate a normal chow diet (Control group); BPA treated mice that also ate a normal chow diet (BPA); vehicle treated animals that had a high fat diet (HFD) and BPA treated animals that were fed HFD (HFD-BPA). The BPA group started to gain weight at 18 weeks old and caught up to the HFD group before week 28. The BPA group as well as the HFD and HFD-BPA ones presented fasting hyperglycemia, glucose intolerance and high levels of non-esterified fatty acids (NEFA) in plasma compared with the Control one. Glucose stimulated insulin release was disrupted, particularly in the HFD-BPA group. In WAT, the mRNA expression of the genes involved in fatty acid metabolism, Srebpc1, Pparα and Cpt1β was decreased by BPA to the same extent as with the HFD treatment. BPA treatment upregulated Pparγ and Prkaa1 genes in the liver; yet it diminished the expression of Cd36. Hepatic triglyceride levels were increased in all groups compared to control. In conclusion, male offspring from BPA-treated mothers presented symptoms of diabesity. This term refers to a form of diabetes which typically develops in later life and is associated with obesity.Bisphenol-A (BPA) is one of the most widespread EDCs used as a base compound in the manufacture of polycarbonate plastics. The aim of our research has been to study how the exposure to BPA during pregnancy affects weight, glucose homeostasis, pancreatic β96113sem informaçãosem informaçãosem informaçã