Caracterización y optimización térmica de sistemas en chip mediante emulación con FPGAs

Tesis inédita de la Universidad Complutense de Madrid, Facultad de Informática, Departamento de Arquitectura de Computadores y Automática, leída el 15/06/2012Tablets and smartphones are some of the many intelligent devices that dominate the consumer electronics market. These systems are complex to design as they must execute multiple applications (e.g.: real-time video processing, 3D games, or wireless communications), while meeting additional design constraints, such as low energy consumption, reduced implementation size and, of course, a short time-to-market. Internally, they rely on Multi-processor Systems on Chip (MPSoCs) as their main processing cores, to meet the tight design constraints: performance, size, power consumption, etc. In a bad design, the high logic density may generate hotspots that compromise the chip reliability. This thesis introduces a FPGA-based emulation framework for easy exploration of SoC design alternatives. It provides fast and accurate estimations of performance, power, temperature, and reliability in one unified flow, to help designers tune their system architecture before going to silicon.El estado del arte, en lo que a diseño de chips para empotrados se refiere, se encuentra dominado por los multi-procesadores en chip, o MPSoCs. Son complejos de diseñar y presentan problemas de disipación de potencia, de temperatura, y de fiabilidad. En este contexto, esta tesis propone una nueva plataforma de emulación para facilitar la exploración del enorme espacio de diseño. La plataforma utiliza una FPGA de propósito general para acelerar la emulación, lo cual le da una ventaja competitiva frente a los simuladores arquitectónicos software, que son mucho más lentos. Los datos obtenidos de la ejecución en la FPGA son enviados a un PC que contiene bibliotecas (modelos) SW para calcular el comportamiento (e.g.: la temperatura, el rendimiento, etc...) que tendría el chip final. La parte experimental está enfocada a dos puntos: por un lado, a verificar que el sistema funciona correctamente y, por otro, a demostrar la utilidad del entorno para realizar exploraciones que muestren los efectos a largo plazo que suceden dentro del chip, como puede ser la evolución de la temperatura, que es un fenómeno lento que normalmente requiere de costosas simulaciones software.Depto. de Arquitectura de Computadores y AutomáticaFac. de InformáticaTRUEunpu

Experiencias en la relación disciplinar de la matemática en la carrera de meteorología

Se presenta el método de concebir el proyecto interdisciplinario integrado en la carrera de Meteorología, que tiene como eje rector la interdisciplinariedad y como metodología la formación académica por competencias. Identificadas éstas en cada semestre se ilustra el diseño de Cálculo y Geometría I y II en su contribución al desempeño cognitivo: comprensión, análisis, interpretación y representación y modelación/simulación. Se muestra el sistema de tareas docentes integradas fundamentalmente a la Disciplina Física y a la Disciplina Integradora. Se analizan los resultados: armónica integración de las acciones didácticas entre profesores y una mejor orientación a los alumnos

Accurate Human Tissue Characterization for Energy-Efficient Wireless On-Body Communications

The demand for Wireless Body Sensor Networks (WBSNs) is rapidly increasing due to the revolution in wearable systems demonstrated by the penetration of on-the-body sensors in hospitals, sports medicine and general health-care practices. In WBSN, the body acts as a communication channel for the propagation of electromagnetic (EM) waves, where losses are mainly due to absorption of power in the tissue. This paper shows the effects of the dielectric properties of biological tissues in the signal strength and, for the first time, relates these effects with the human body composition. After a careful analysis of results, this work proposes a reactive algorithm for power transmission to alleviate the effect of body movement and body type. This policy achieves up to 40.8% energy savings in a realistic scenario with no performance overhead

Experimental confirmation of FK concentrator insensitivity to chromatic aberrations

The FK concentrator has demonstrated during the last years that compares very well with other Fresnel-based concentrator optics for CPV. There are several features that provide the FK high performance: (1) high optical efficiency; (2) large tolerance to tracking misalignment and manufacturing errors, thanks to a high CAP (Concentration-Acceptance Product); (3) good irradiance uniformity and low chromatic dispersion on the cell surface. Non-uniformities in terms of absolute irradiance and spectral content produced by conventional CPV systems can originate electrical losses in multi-junction (MJ) solar cells. The aim of this work is to analyze the influence of these non-uniformities in the FK concentrator performance and how FK concentrator provides high electrical efficiencies thanks to its insensitivity to chromatic aberrations, especially when components move away from the module nominal position due to manufacturing misalignments. This analysis has been done here by means of both, experimental on-sun measurements and simulations based on 3D fully distributed circuit model for MJ cells

Autoantigenic nuclear proteins of a clinically atypical renal vasculitis

© 2008 Avila et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Triple-junction solar cell performance under Fresnel-based concentrators taking into account chromatic aberration and off-axis operation

Concentration photovoltaic (CPV) systems might produce quite uneven irradiance distributions (both on their level and on their spectral distribution) on the solar cell. This effect can be even more evident when the CPV system is slightly off-axis, since they are often designed to assure good uniformity only at normal incidence. The non-uniformities both in absolute irradiance and spectral content produced by the CPV systems, can originate electrical losses in multi-junction solar cells (MJSC). This works is focused on the integration of ray-tracing methods for simulating the irradiance and spectrum maps produced by different optic systems throughout the solar cell surface, with a 3D fully distributed circuit model which simulates the electrical behavior of a state-of-the-art triple-junction solar cell under the different light distributions obtained with ray-tracing. In this study four different CPV system (SILO, XTP, RTP, and FK) comprising Fresnel lenses concentrating sunlight onto the same solar cell are modeled when working on-axis and 0.6 degrees off-axis. In this study the impact of non-uniformities on a CPV system behavior is revealed. The FK outperforms other Fresnel-based CPV systems in both on-axis and off-axis conditions

Dasatinib-induced spleen contraction leads to transient lymphocytosis

The tyrosine kinase inhibitor dasatinib is approved for Philadelphia chromosome–positive leukemia, including chronic myeloid leukemia (CML). Although effective and well tolerated, patients typically exhibit a transient lymphocytosis after dasatinib uptake. To date, the underlying physiological process linking dasatinib to lymphocytosis remains unknown. Here, we used a small rodent model to examine the mechanism of dasatinib-induced lymphocytosis, focusing on lymphocyte trafficking into and out of secondary lymphoid organs. Our data indicate that lymphocyte homing to lymph nodes and spleen remained unaffected by dasatinib treatment. In contrast, dasatinib promoted lymphocyte egress from spleen with kinetics consistent with the observed lymphocytosis. Unexpectedly, dasatinib-induced lymphocyte egress occurred independently of canonical sphingosine-1-phosphate–mediated egress signals; instead, dasatinib treatment led to a decrease in spleen size, concomitant with increased splenic stromal cell contractility, as measured by myosin light chain phosphorylation. Accordingly, dasatinib-induced lymphocytosis was partially reversed by pharmacological inhibition of the contraction-promoting factor Rho-rho associated kinase. Finally, we uncovered a decrease in spleen size in patients with CML who showed lymphocytosis immediately after dasatinib treatment, and this reduction was proportional to the magnitude of lymphocytosis and dasatinib plasma levels. In summary, our work provides evidence that dasatinib-induced lymphocytosis is a consequence of drug-induced contractility of splenic stromal cell

Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material

Gene therapy is a therapeutic process consisting of the transport of genetic material into cells. The design and preparation of novel carriers to transport DNA is an important research line in the medical field. Hybrid compounds such as metallo-liposomes, containing a mixture of lipids, were prepared and characterized. Cationic metal lipids derived from the [Ru(bpy)3]2+ complex, RuC11C11 or RuC19C19, both with different hydrophobic/lipophilic ratios, were mixed with the phospholipid DOPE. A relation between the size and the molar fraction α was found and a multidisciplinary study about the interaction between the metallo-liposomes and DNA was performed. The metallo-liposomes/DNA association was quantified and a relationship between Kapp and α was obtained. Techniques such as AFM, SEM, zeta potential, dynamic light scattering and agarose gel electrophoresis demonstrated the formation of lipoplexes and showed the structure of the liposomes. L/D values corresponding to the polynucleotide's condensation were estimated. In vitro assays proved the low cell toxicity of the metallo-liposomes, lower for normal cells than for cancer cell lines, and a good internalization into cells. The latter as well as the transfection measurements carried out with plasmid DNA pEGFP-C1 have demonstrated a good availability of the Ru(II)-based liposomes for being used as non-toxic nanovectors in gene therapy.España Consejería de Educación y Ciencia de la Junta de Andalucía (Proyecto de Excelencia P12-FQM-1105, FQM-206 and FQM-274, and PI-0005-2018)España,, Universidad de Sevilla, VI Plan Propio Universidad de Sevilla (PP2018-10338)España Ministerio de Ciencia, Innovación y Universidades (RTI2018-100692-B-I00

Anexo 1 - Ficha de Evaluación - Trabajo Fin de Grado - Grado en Trabajo Social

Este documento contiene el Anexo 1 de la memoria del Proyecto de Innovación Docente "Diseño y elaboración de rúbricas de evaluación de competencias del Trabajo Fin de Grado y del Prácticum en el Grado de Trabajo Social". Específicamente, este anexo contiene la rúbrica realizada para la evaluación del Trabajo Fin de Grado del Grado en Trabajo Social.Departamento de Sociología y Trabajo SocialEste trabajo se ha llevado a cabo en el marco de la Convocatoria de Proyectos de Innovación Docente 2015-2016 - Universidad de Valladoli

Anexo 2 - Ficha de Evaluación - Prácticum I y II - Grado en Trabajo Social

Innovación EducativaEste documento contiene el Anexo 2 de la memoria del Proyecto de Innovación Docente "Diseño y elaboración de rúbricas de evaluación de competencias del Trabajo Fin de Grado y del Prácticum en el Grado de Trabajo Social. Específicamente, este anexo contiene la rúbrica realizada para la evaluación del Prácticum I y Prácticum II del Grado en Trabajo Social de la Universidad de Valladolid.Departamento de Sociología y Trabajo SocialEste trabajo se ha llevado a cabo en el marco de la Convocatoria de Proyectos de Innovación Docente 2015-2016 - Universidad de Valladoli