Nutrition, bioenergetics, and metabolic syndrome

According to the World Health Organization (WHO), the global nutrition report shows that whilst part of the world's population starves, the other part suffers from obesity and associated complications. A balanced diet counterparts these extreme conditions with the proper proportion, composition, quantity, and presence of macronutrients, micronutrients, and bioactive compounds. However, little is known on the way these components exert any influence on our health. These nutrients aiming to feed our bodies, our tissues, and our cells, first need to reach mitochondria, where they are decomposed into CO2 and H2O to obtain energy. Mitochondria are the powerhouse of the cell and mainly responsible for nutrients metabolism, but they are also the main source of oxidative stress and cell death by apoptosis. Unappropriated nutrients may support mitochondrial to become the Trojan horse in the cell. This review aims to provide an approach to the role that some nutrients exert on mitochondria as a major contributor to high prevalent Western conditions including metabolic syndrome (MetS), a constellation of pathologic conditions which promotes type II diabetes and cardiovascular risk. Clinical and experimental data extracted from in vitro animal and cell models further demonstrated in patients, support the idea that a balanced diet, in a healthy lifestyle context, promotes proper bioenergetic and mitochondrial function, becoming the best medicine to prevent the onset and progression of MetS. Any advance in the prevention and management of these prevalent complications help to face these challenging global health problems, by ameliorating the quality of life of patients and reducing the associated sociosanitary burden

Control corporativo y riqueza de los accionistas en el sector eléctrico europeo

Este artículo analiza el efecto de los anuncios de cambios en el control corporativo (Ofertas Públicas de Adquisición - OPA) sobre el precio de cotización en Bolsa de Endesa, Hidrocantábrico y Scottish Power y el impacto que estos acontecimientos tienen sobre los rendimientos de los competidores más cercanos a la empresa OPAda. Por medio de la metodología de “estudio de acontecimiento”, empleando modelos GARCH y MCO, se encuentra que las OPA lanzadas sobre estas empresas hacen que ellas presenten rendimientos anormales positivos, estadísticamente significativos a un nivel del 1%. Los resultados también sugieren que en industrias con alto poder de mercado, el anuncio del lanzamiento de una OPA tiene un impacto positivo estadísticamente significativo sobre los rendimientos de los competidores más cercanos a la empresa OPAda.This paper analyzes how announcel changes in the corporate control (takeover) of Endesa, Hidrocantábrico and Scottish Power affect their stock market returns and the impact that these events have on the stock market returns of competitors of the target firm. Using an “event study” methodology we find that takeovers positively and significantly affect at the 1% level, the stock market return of the target firm. Results are robust across several econometric specifications as GARCH and MCO models. Also, the results suggest the announcement of the launching of a takeover positively and significantly affects the stock market return of the target firm´s competitors in industries with high market power

European energy industry shocks, corporate control and firm's value

The deregulation process in the EU electricity sector triggered strategic decisions that led to industry restructuring. This paper presents preliminary evidence of the impact of this process on investors, using event studies and estimation techniques such as least squares and GARCH. Our findings suggest three stylized facts: 1) regulatory reform in Europe was certainly accompanied by a takeover wave, as predicted by Mitchell and Mulherin (1996); 2) mergers and acquisitions had a positive impact on the stock price of target firms, and a much lower and sometimes even a negative impact for the bidding firms; 3) the effect of takeover announcements on the returns of competitors of the merging firms depends on the degree of market power. In countries with high market power (like Spain) competitors significantly increase share returns upon takeover announcements, whereas in countries with lower market power (like England and Wales) returns do not change significantly

Regulatory Reform and Corporate Control in European Energy Industries

The deregulation process in the EU electricity sector triggered strategic decisions that led to industry restructuring. This paper presents preliminary evidence of the impact of this process on investors, using event studies and estimation techniques such as least squares and GARCH. Our findings suggest three stylized facts: 1) regulatory reform in Europe was certainly accompanied by a takeover wave, as predicted by Mitchell and Mulherin (1996); 2) mergers and acquisitions had a positive impact on the stock price of target firms, and a much lower and sometimes even a negative impact for the bidding firms; 3) the effect of takeover announcements on the returns of competitors of the merging firms depends on the degree of market power. In countries with high market power (like Spain) competitors significantly increase share returns upon takeover announcements, whereas in countries with lower market power (like England and Wales) returns do not change significantly

Reforma regulatoria energética en Europa: impacto de los cambios de control corporativo sobre el valor de las empresas

El proceso de desregulación del sector eléctrico en la Unión Europea generó acciones estratégicas de parte de las empresas del sector que han llevado al reordenamiento de su mercado de energía eléctrica. Una serie de fusiones y adquisiciones ocurrieron a raíz de ese proceso. Este trabajo investiga cómo la consecuente ola de fusiones y adquisiciones que se dio en la primera década de este siglo ha afectado el valor en bolsa de las empresas compradoras y adquiridas. Para este propósito, haciendo uso de la metodología de los estudios de acontecimiento y con técnicas econométricas de MCO, GARCH y SURE se encontró que las fusiones y adquisiciones presentaron un efecto positivo estadísticamente significativo sobre el precio de cotización en bolsa para la empresa objeto de compra (u opada), lo cual es consistente con estudios previos.The deregulation process of the European power sector generated strategic moves by the power companies leading to a complete reordering of the European electric market that brought out an upsurge of mergers and acquisitions. This paper researches how the following wave of mergers and acquisitions that took place in the 2000 impacted the market value for the acquiring and selling companies that took part of it. With this objective and making use of the event study methodology, and OLS, GARCH, and SURE econometric techniques, we found that mergers and acquisitions had a positive and significant effect on the average market price in public stock exchanges for the companies that were target which is consistent with previous studies

El poder de mercado bajo el nuevo diseño del Pool eléctrico Español

During 2006 and 2007, by means of the Royal Decree Law 3/2006, the Royal Decree 1634/2006 and the Order ITC/400/2007, several changes were introduced in the running of the wholesale electricity market in Spain. One of the objectives of these measures was to diminish the market power in the industry. This chapter intends to measure this market power by the difference between observed wholesale market prices and estimates of competitive benchmark price. This methodology has been used previously in the United Kingdom and California (Sweeting (2007) and Boresntein et al. (2002)), but has not been used so far in the electricity generation industry in Spain. The market power is reduced in the second quarter of 2006, but it increased again in the third quarter of 2007 and reached levels similar to the ones at the beginning of 2004 (0.43)During 2006 and 2007, by means of the Royal Decree Law 3/2006, the Royal Decree 1634/2006 and the Order ITC/400/2007, several changes were introduced in the running of the wholesale electricity market in Spain. One of the objectives of these measures was to diminish the market power in the industry. This chapter intends to measure this market power by the difference between observed wholesale market prices and estimates of competitive benchmark price. This methodology has been used previously in the United Kingdom and California (Sweeting (2007) and Boresntein et al. (2002)), but has not been used so far in the electricity generation industry in Spain. The market power is reduced in the second quarter of 2006, but it increased again in the third quarter of 2007 and reached levels similar to the ones at the beginning of 2004 (0.43

Residents' Perception of the Impact of Sports Tourism on Sustainable Social Development

The analysis of the social perception of citizens and evaluations of the impact of sport tourism and their support for tourism development can be of great use in the formulation of policies aimed at social cohesion and local development. These actions favor social participation and inclusion, equal opportunities, and more positive attitudes towards sports tourism and inclusive sport. This study aims to analyze the perception and predisposition towards the support of citizens on the impact of sport tourism from a multidimensional perspective. Specifically, this study evaluates the social perception on four measures: social impact, cultural impact, environmental impact, and local policies. The sample of this study is composed of 607 people living in Gran Canaria. A survey with two scales were used, one on the perception of the social, cultural, environmental, economic, and political-administrative impact and the other was on the predisposition to support the development of sport tourism from the perspective of sustainable and inclusive social development. Using the partial least square methodology, the results show that all the study variables were significant except for social impact. It is concluded that there is a favorable social perception towards sport tourism. The results of this study might have a effect on the planning of the tourism sector in Gran Canaria as well as on the policies and regulations governing this activity

Maldi-imaging for proteomics of protease inhibitors

Comunicaciones a congreso