3,169 research outputs found
NewsPad: Designing for Collaborative Storytelling in Neighborhoods
This paper introduces design explorations in neighborhood collaborative
storytelling. We focus on blogs and citizen journalism, which have been
celebrated as a means to meet the reporting needs of small local communities.
These bloggers have limited capacity and social media feeds seldom have the
context or readability of news stories. We present NewsPad, a content editor
that helps communities create structured stories, collaborate in real time,
recruit contributors, and syndicate the editing process. We evaluate NewsPad in
four pilot deployments and find that the design elicits collaborative story
creation.Comment: NewsPad: designing for collaborative storytelling in neighborhoods.
In Proceedings of the extended abstracts of the 32nd annual ACM conference on
Human factors in computing systems (CHI EA 2014
Preventing Pseudomonas aeruginosa and Chromobacterium violaceum infections by anti-adhesion-active components of edible seeds
<p>Abstract</p> <p>Background</p> <p><it>Pseudomonas aeruginosa </it>adhesion to animal/human cells for infection establishment involves adhesive proteins, including its galactose- and fucose-binding lectins PA-IL (LecA) and PA-IIL (LecB). The lectin binding to the target-cell receptors may be blocked by compatible glycans that compete with those of the receptors, functioning as anti-adhesion glycodecoys. The anti-adhesion treatment is of the utmost importance for abrogating devastating antibiotic-resistant <it>P. aeruginosa </it>infections in immunodeficient and cystic fibrosis (CF) patients. This strategy functions in nature in protecting embryos and neonates. We have shown that PA-IL, PA-IIL, and also CV-IIL (a PA-IIL homolog produced in the related pathogen <it>Chromobacterium violaceum</it>) are highly useful for revealing natural glycodecoys that surround embryos in diverse avian eggs and are supplied to neonates in milks and royal jelly. In the present study, these lectins were used as probes to search for seed embryo-protecting glycodecoys.</p> <p>Methods</p> <p>The lectin-blocking glycodecoy activities were shown by the hemagglutination-inhibition test. Lectin-binding glycoproteins were detected by Western blotting with peroxidase-labeled lectins.</p> <p>Results</p> <p>The present work reports the finding - by using PA-IL, PA-IIL, and CV-IIL - of rich glycodecoy activities of low (< 10 KDa) and high MW (> 10 kDa) compounds (including glycoproteins) in extracts of cashew, cocoa, coffee, pumpkin, and tomato seeds, resembling those of avian egg whites, mammal milks, and royal jelly.</p> <p>Conclusions</p> <p>Edible seed extracts possess lectin-blocking glycodecoys that might protect their embryos from infections and also might be useful for hampering human and animal infections.</p
Examination Free-Flow Speed Distribution on Two-Lane Rural Roads
[EN] Free-flow speed variation of passenger vehicles along a road segment is one of the most used factors in road safety studies, as a surrogate measure to evaluate road design consistency. Free-flow speed may be measured when a road segment is already built but must be estimated during the design phase. Several studies have been carried out to calibrate models to estimate free-flow speed, with geometric features as explanatory variables. Currently, most free-flow speed models focus only on mean speed or speed in particular percentiles, such as the 85th or 95th. Moreover, most studies have assumed normality in the free-flow speed distribution without checking this hypothesis. The main objective of this study was to analyze the free-flow speed distribution on two-lane rural road curves and tangents. The research focused on two main issues: determining whether speed data were normally distributed at a specific site and analyzing the behavior of the mean and standard deviation of speed on curves and tangents. The study was based on continuous operating speed profiles, which were obtained from a database of more than 16,000 vehicles/km. A total of 63 horizontal curves and 78 tangents were analyzed. According to the results, the normal distribution is not the best distribution in most cases for describing free-flow speeds. In 46 of the curves and 64 of the tangents, free-flow speed cannot be assumed to be normally distributed. Therefore, some other distributions should be tested in further research.The study presented in this paper is part of the research project CASEFU-Estudio experimental de la funcionalidad y seguridad de las carreteras convencionales, subsidized by the Spanish Ministry of Economy and Competitiveness and the European Social Fund. In addition, the authors thank the Center for Studies and Experimentation of Public Works of the Spanish Ministry of Public Works for subsidizing the field data collection, and the Infrastructure and Transportation Department of the General Directorate of Public Works of the Valencian Government, the Valencian Provincial Council, and the Ministry of the Interior, especially the General Directorate of Traffic of Spain, for their cooperation in gathering the field data.GarcĂa JimĂŠnez, ME.; PĂŠrez Zuriaga, AM.; Llopis-CastellĂł, D.; Camacho Torregrosa, FJ.; GarcĂa GarcĂa, A. (2016). Examination Free-Flow Speed Distribution on Two-Lane Rural Roads. Transportation Research Record Journal of the Transportation Research Board. 2556:86-97. https://doi.org/10.3141/2556-09S8697255
Linguistic incompetence: giving an account of researching multilingually
This paper considers the place of linguistic competence and incompetence in the context of researching multilingually. It offers a critique of the concept of competence and explores the performative dimensions of multilingual research and its narration, through the philosophy of Judith Butler, and in particular her study Giving an account of oneself. It explores aspects of risk, justice, narrative limit and a morality of multilingualism in emergent multilingual research frameworks. These theoretical dimensions are explored through consideration of âlinguistically incompetentâ ethnographic work with refugees and asylum seekers, in contexts of hospitality and in life long learning research in the Gaza Strip, and of early attempts to learn new languages. The paper offers a prospect of a relational approach to researching multilingually and affirms the vulnerability at the heart of linguistic hospitality
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Postdeployment military mental health training: Cross-national evaluations
Deployments increase risk for adjustment problems in service members. To mitigate this increased risk, mental health training programs have been developed and implemented in several nations. As part of a coordinated effort, three nations adapted a U.S. mental health training program that had been validated by a series of group randomized trials demonstrating improvement in postdeployment adjustment. Implementation of evidence-based programs in a new context is challenging: How much of the original program needs to remain intact in order to retain its utility? User satisfaction rates can provide essential data to assess how well a program is accepted. This article summarizes service member ratings of postdeployment mental health training and compares ratings from service members across four nations. The participating nations (Canada, New Zealand, United Kingdom, and the United States) administered mental health training to active duty military personnel in their respective nations. Following the training, military personnel completed an evaluation of the training. Overall, across the four nations, more than 70% of military personnel agreed or strongly agreed that they were satisfied with the mental health training. Although some differences in evaluations were observed across nations, components of training that were most important to overall satisfaction with the training were strikingly similar across nations. Fundamentally, it appears feasible that despite cultural and organizational differences, a mental health training program developed in one nation can be successfully adapted for use in other nations
Evaluating the effects of bilingual traffic signs on driver performance and safety
Variable Message Signs (VMS) can provide immediate and relevant information to road users and bilingual VMS can provide great flexibility in countries where a significant proportion of the population speak an alternative language to the majority. The study reported here evaluates the effect of various bilingual VMS configurations on driver behaviour and safety. The aim of the study was to determine whether or not the visual distraction associated with bilingual VMS signs of different configurations (length, complexity) impacted on driving performance. A driving simulator was used to allow full control over the scenarios, road environment and sign configuration and both longitudinal and lateral driver performance was assessed. Drivers were able to read one and two-line monolingual signs and two-line bilingual signs without disruption to their driving behaviour. However, drivers significantly reduced their speed in order to read four-line monolingual and four-line bilingual signs, accompanied by an increase in headway to the vehicle in front. This implies that drivers are possibly reading the irrelevant text on the bilingual sign and various methods for reducing this effect are discussed
Teleology and Realism in Leibniz's Philosophy of Science
This paper argues for an interpretation of Leibnizâs claim that physics requires both mechanical and teleological principles as a view regarding the interpretation of physical theories. Granting that Leibnizâs fundamental ontology remains non-physical, or mentalistic, it argues that teleological principles nevertheless ground a realist commitment about mechanical descriptions of phenomena. The empirical results of the new sciences, according to Leibniz, have genuine truth conditions: there is a fact of the matter about the regularities observed in experience. Taking this stance, however, requires bringing non-empirical reasons to bear upon mechanical causal claims. This paper first evaluates extant interpretations of Leibnizâs thesis that there are two realms in physics as describing parallel, self-sufficient sets of laws. It then examines Leibnizâs use of teleological principles to interpret scientific results in the context of his interventions in debates in seventeenth-century kinematic theory, and in the teaching of Copernicanism. Leibnizâs use of the principle of continuity and the principle of simplicity, for instance, reveal an underlying commitment to the truth-aptness, or approximate truth-aptness, of the new natural sciences. The paper concludes with a brief remark on the relation between metaphysics, theology, and physics in Leibniz
Developing and applying heterogeneous phylogenetic models with XRate
Modeling sequence evolution on phylogenetic trees is a useful technique in
computational biology. Especially powerful are models which take account of the
heterogeneous nature of sequence evolution according to the "grammar" of the
encoded gene features. However, beyond a modest level of model complexity,
manual coding of models becomes prohibitively labor-intensive. We demonstrate,
via a set of case studies, the new built-in model-prototyping capabilities of
XRate (macros and Scheme extensions). These features allow rapid implementation
of phylogenetic models which would have previously been far more
labor-intensive. XRate's new capabilities for lineage-specific models,
ancestral sequence reconstruction, and improved annotation output are also
discussed. XRate's flexible model-specification capabilities and computational
efficiency make it well-suited to developing and prototyping phylogenetic
grammar models. XRate is available as part of the DART software package:
http://biowiki.org/DART .Comment: 34 pages, 3 figures, glossary of XRate model terminolog
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