Advanced subsonic transport approach noise: The relative contribution of airframe noise

With current engine technology, airframe noise is a contributing source for large commercial aircraft on approach, but not the major contributor. With the promise of much quieter jet engines with the planned new generation of high-by-pass turbofan engines, airframe noise has become a topic of interest in the advanced subsonic transport research program. The objective of this paper is to assess the contribution of airframe noise relative to the other aircraft noise sources on approach. The assessment will be made for a current technology large commercial transport aircraft and for an envisioned advanced technology aircraft. NASA's Aircraft Noise Prediction Program (ANOPP) will be used to make total aircraft noise predictions for these two aircraft types. Predicted noise levels and areas of noise contours will be used to determine the relative importance of the contributing approach noise sources. The actual set-up decks used to make the ANOPP runs for the two aircraft types are included in appendixes

Long-range vertical propagation

Development of the advanced turboprop has led to concerns about en route noise. Advanced turboprops generate low-frequency, periodic noise signatures at relatively high levels. As demonstrated in a flight test of NASA Lewis Research Center's Propfan Test Assessment (PTA) airplane in Alabama in October 1987, the noise of an advanced turboprop operating at cruise altitudes can be audible on the ground. The assessment of the en route noise issue is difficult due to the variability in received noise levels caused by atmospheric propagation and the uncertainty in predicting community response to the relatively low-level en route noise, as compared to noise associated with airport operations. The En Route Noise Test was designed to address the atmospheric propagation of advanced turboprop noise from cruise altitudes and consisted of measuring the noise of an advance turboprop at cruise in close proximity to the turboprop and on the ground. Measured and predicted ground noise levels are presented

PTA en route noise measurements

A long-range advanced turboprop en route noise database was obtained with weather, tracking, and onboard measurements. In-flight noise directivity measurements were made. Data repeatability within a test day was excellent. Day-to-day variability existed and is not completely understood and therefore not predicted. Comparison of a two-dimensional ray-tracing propagation model with the ensemble average ground-measured data was good; however, as stated above, the day-to-day data variability was not completely predicted. Future research will include looking at alternative propagation models. Three-dimensional ray tracing, fast field program, and the parabolic equation are possibilities. The effect of turbulence needs to be accessed

On the use of the noncentral chi-square density function for the distribution of helicopter spectral estimates

A probability density function for the variability of ensemble averaged spectral estimates from helicopter acoustic signals in Gaussian background noise was evaluated. Numerical methods for calculating the density function and for determining confidence limits were explored. Density functions were predicted for both synthesized and experimental data and compared with observed spectral estimate variability

Evaluation of a nonlinear method for the enhancement of tonal signal detection

A method is presented for biasing spectral estimates to enhance detection of tonal signals against a background of broadband noise. In this method, a nonlinear average of an ensemble of individual spectral estimates is made where broadband noise energy is biased downward, pure tone energy is unbiased, and a mixture of the two is biased by an amount that depends on the ratio of tonal energy to broadband energy. The method is analyzed to provide estimates of the extent of tonal signal detection enhancement

En route noise levels from propfan test assessment airplane

The en route noise test was designed to characterize propagation of propfan noise from cruise altitudes to the ground. In-flight measurements of propfan source levels and directional patterns were made by a chase plane flying in formation with the propfan test assessment (PTA) airplane. Ground noise measurements were taken during repeated flights over a distributed microphone array. The microphone array on the ground was used to provide ensemble-averaged estimates of mean flyover noise levels, establish confidence limits for those means, and measure propagation-induced noise variability. Even for identical nominal cruise conditions, peak sound levels for individual overflights varied substantially about the average, particularly when overflights were performed on different days. Large day-to-day variations in peak level measurements appeared to be caused by large day-to-day differences in propagation conditions and tended to obscure small variations arising from operating conditions. A parametric evaluation of the sensitivity of this prediction method to weather measurement and source level uncertainties was also performed. In general, predictions showed good agreement with measurements. However, the method was unable to predict short-term variability of ensemble-averaged data within individual overflights. Although variations in absorption appear to be the dominant factor in variations of peak sound levels recorded on the ground, accurate predictions of those levels require that a complete description of operational conditions be taken into account. The comprehensive and integrated methods presented in this paper have adequately predicted ground-measured sound levels. On average, peak sound levels were predicted within 3 dB for each of the three different cruise conditions

The Calibration of AVHRR Visible Dual Gain using Meteosat-8 for NOAA-16 to 18

The NOAA AVHRR program has given the remote sensing community over 25 years of imager radiances to retrieve global cloud, vegetation, and aerosol properties. This dataset can be used for long-term climate research, if the AVHRR instrument is well calibrated. Unfortunately, the AVHRR instrument does not have onboard visible calibration and does degrade over time. Vicarious post-launch calibration is necessary to obtain cloud properties that are not biased over time. The recent AVHRR-3 instrument has a dual gain in the visible channels in order to achieve greater radiance resolution in the clear-sky. This has made vicarious calibration of the AVHRR-3 more difficult to unravel. Reference satellite radiances from well-calibrated instruments, usually equipped with solar diffusers, such as MODIS, have been used to successfully vicariously calibrate other visible instruments. Transfer of calibration from one satellite to another using co-angled, collocated, coincident radiances has been well validated. Terra or Aqua MODIS and AVHRR comparisons can only be performed over the poles during summer. However, geostationary satellites offer a transfer medium that captures both parts of the dual gain. This AVHRR-3 calibration strategy uses, calibrated with MODIS, Meteosat-8 radiances simultaneously to determine the dual gains using 50km regions. The dual gain coefficients will be compared with the nominal coefficients. Results will be shown for all visible channels for NOAA-17

Climate Quality Broadband and Narrowband Solar Reflected Radiance Calibration Between Sensors in Orbit

vAs the potential impacts of global climate change become more clear [1], the need to determine the accuracy of climate prediction over decade-to-century time scales has become an urgent and critical challenge. The most critical tests of climate model predictions will occur using observations of decadal changes in climate forcing, response, and feedback variables. Many of these key climate variables are observed by remotely sensing the global distribution of reflected solar spectral and broadband radiance. These "reflected solar" variables include aerosols, clouds, radiative fluxes, snow, ice, vegetation, ocean color, and land cover. Achieving sufficient satellite instrument accuracy, stability, and overlap to rigorously observe decadal change signals has proven very difficult in most cases and has not yet been achieved in others [2]. One of the earliest efforts to make climate quality observations was for Earth Radiation Budget: Nimbus 6/7 in the late 1970s, ERBE in the 1980s/90s, and CERES in 2000s are examples of the most complete global records. The recent CERES data products have carried out the most extensive intercomparisons because if the need to merge data from up to 11 instruments (CERES, MODIS, geostationary imagers) on 7 spacecraft (Terra, Aqua, and 5 geostationary) for any given month. In order to achieve climate calibration for cloud feedbacks, the radiative effect of clear-sky, all-sky, and cloud radiative effect must all be made with very high stability and accuracy. For shortwave solar reflected flux, even the 1% CERES broadband absolute accuracy (1-sigma confidence bound) is not sufficient to allow gaps in the radiation record for decadal climate change. Typical absolute accuracy for the best narrowband sensors like SeaWiFS, MISR, and MODIS range from 2 to 4% (1-sigma). IPCC greenhouse gas radiative forcing is approx. 0.6 W/sq m per decade or 0.6% of the global mean shortwave reflected flux, so that a 50% cloud feedback would change the global reflected flux by approx. 0.3 W/sq m or 0.3% per decade in broadband SW calibration change. Recent results comparing CERES reflected flux changes with MODIS, MISR, and SeaWiFS narrowband changes concluded that only SeaWiFS and CERES were approaching sufficient stability in calibration for decadal climate change [3]. Results using deep convective clouds in the optically thick limit as a stability target may prove very effective for improving past data sets like ISCCP. Results for intercalibration of geostationary imagers to CERES using an entire month of regional nearly coincident data demonstrates new approaches to constraining the calibration of current geostationary imagers. The new Decadal Survey Mission CLARREO is examining future approaches to a "NIST-in-Orbit" approach of very high absolute accuracy reference radiometers that cover the full solar and infrared spectrum at high spectral resolution but at low spatial resolution. Sampling studies have shown that a precessing CLARREO mission could calibrate other geo and leo reflected solar radiation and thermal infrared sensors

Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

<p>Abstract</p> <p>Background</p> <p>A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is coupled with the transcriptional repression of E-cadherin, often mediated by Snail1, Snail2 and Zeb1/δEF1. These genes, overexpressed in breast carcinomas, are known targets of growth factor-initiated pathways, however it is less clear how alterations in ECM attachment cross-modulate to regulate these pathways. EGF induces EMT in the breast cancer cell line PMC42-LA and the kinase inhibitor staurosporine (ST) induces EMT in embryonic neural epithelial cells, with F-actin de-bundling and disruption of cell-cell adhesion, via inhibition of aPKC.</p> <p>Methods</p> <p>PMC42-LA cells were treated for 72 h with 10 ng/ml EGF, 40 nM ST, or both, and assessed for expression of E-cadherin repressor genes (Snail1, Snail2, Zeb1/δEF1) and EMT-related genes by QRT-PCR, multiplex tandem PCR (MT-PCR) and immunofluorescence +/- cycloheximide. Actin and focal contacts (paxillin) were visualized by confocal microscopy. A public database of human breast cancers was assessed for expression of Snail1 and Snail2 in relation to outcome.</p> <p>Results</p> <p>When PMC42-LA were treated with EGF, Snail2 was the principal E-cadherin repressor induced. With ST or ST+EGF this shifted to Snail1, with more extreme EMT and Zeb1/δEF1 induction seen with ST+EGF. ST reduced stress fibres and focal contact size rapidly and independently of gene transcription. Gene expression analysis by MT-PCR indicated that ST repressed many genes which were induced by EGF (EGFR, CAV1, CTGF, CYR61, CD44, S100A4) and induced genes which alter the actin cytoskeleton (NLF1, NLF2, EPHB4). Examination of the public database of breast cancers revealed tumours exhibiting higher Snail1 expression have an increased risk of disease-recurrence. This was not seen for Snail2, and Zeb1/δEF1 showed a reverse correlation with lower expression values being predictive of increased risk.</p> <p>Conclusion</p> <p>ST in combination with EGF directed a greater EMT via actin depolymerisation and focal contact size reduction, resulting in a loosening of cell-ECM attachment along with Snail1-Zeb1/δEF1 induction. This appeared fundamentally different to the EGF-induced EMT, highlighting the multiple pathways which can regulate EMT. Our findings add support for a functional role for Snail1 in invasive breast cancer.</p