Helminth infections, atopy, asthma and allergic diseases: protocol for a systematic review of observational studies worldwide.

INTRODUCTION: Childhood infections, particularly those caused by helminths are considered to be important environmental exposures influencing the development of allergic diseases. However, epidemiological studies focusing on the relationship between helminth infections and risk of allergic diseases, performed worldwide, show inconsistent findings. Previous systematic reviews of observational studies published 10 or more years ago showed conflicting findings for effects of helminths on allergic diseases. Over the past 10 years there has been growing literature addressing this research area and these need to be considered in order to appreciate the most contemporary evidence. The objective of the current systematic review will be to provide an up-to-date synthesis of findings of observational studies investigating the influence of helminth infections on atopy, and allergic diseases. METHODS AND ANALYSIS: This systematic review protocol was registered at PROSPERO. We will search Cochrane Library, MEDLINE, EMBASE, CINAHL, AMED, ISI Web of Science, WHO Global Health Library, Scielo, IndMed, PakMediNet, KoreaMed, Ichushi for published studies from 1970 to January 2020. Bibliographies of all eligible studies will be reviewed to identify additional studies. Unpublished and ongoing research will also be searched in key databases. There will be no language or geographical restrictions regarding publications. Critical Appraisal Skills Programme quality assessment tool will be used to appraise methodological quality of included studies. A descriptive summary with data tables will be constructed, and if adequate, meta-analysis using random-effects will be performed. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist will be followed for reporting of the systematic review. ETHICS AND DISSEMINATION: Since this systematic review will be only based on published and retrievable literature, no ethics approval will be sought. The multidisciplinary team performing this systematic review will participate in relevant dissemination activities. Findings will be presented at scientific meetings and publish the systematic review in international, peer-reviewed, open-access journals. PROSPERO REGISTRATION NUMBER: CRD42020167249

Pelatihan Bahasa Inggris Bagi Guru Tk di Kalurahan Dukuh, Kecamatan Mojolaban Sukoharjo

Kemampuan mengajar Bapak / Ibu guru TK di desa Dukuh dalam bahasa Inggris untuk anak anak belum memiliki dasar pelatihan sama sekali dan dalam melakukan komunikasi dengan menggunakan bahasa Inggris dipandang sangat kurang. Hal ini disebabkan karena Bapak/ Ibu guru tidak memiliki latar belakang pendidikan bahasa Inggris. Bahasa Inggris dewasa kini sangat penting sekali, dikarenakan menjadi bahasa global yang wajib dikuasai dalam masyarakat global. Oleh karena itu sangat penting mengajarkan dan mengenalkan bahasa inggris kepada anak- anak sedini mungkin. Agar mereka dapat mengenal dan menyenangi bahasa Inggris. Bapak / Ibu guru TK di desa dukuh perlu adanya pelatihan mengajar bahasa Inggris untuk anak anak TK supaya mereka senang dan bahagia belajar bahasa Inggris. Oleh karena itu untuk meningkatkan kualitas sumber daya manusia mitra maka kegiatan pengabdian kepada masyarakat dilakukan dalam bentuk: Program Short Course Bahasa Inggris, Program Pengadaan media pembelajaran bahasa Inggris yang berupa buku ajar English for young learner, Program Penguatan Kompetensi Kebahasaan dan program mengajar bahasa Inggris untuk anak TK

Diffusion-limited deposition of dipolar particles

Deposits of dipolar particles are investigated by means of extensive Monte Carlo simulations. We found that the effect of the interactions is described by an initial, non-universal, scaling regime characterized by orientationally ordered deposits. In the dipolar regime, the order and geometry of the clusters depend on the strength of the interactions and the magnetic properties are tunable by controlling the growth conditions. At later stages, the growth is dominated by thermal effects and the diffusion-limited universal regime obtains, at finite temperatures. At low temperatures the crossover size increases exponentially as T decreases and at T=0 only the dipolar regime is observed.Comment: 5 pages, 4 figure

Improving adaptive bagging methods for evolving data streams

We propose two new improvements for bagging methods on evolving data streams. Recently, two new variants of Bagging were proposed: ADWIN Bagging and Adaptive-Size Hoeffding Tree (ASHT) Bagging. ASHT Bagging uses trees of different sizes, and ADWIN Bagging uses ADWIN as a change detector to decide when to discard underperforming ensemble members. We improve ADWIN Bagging using Hoeffding Adaptive Trees, trees that can adaptively learn from data streams that change over time. To speed up the time for adapting to change of Adaptive-Size Hoeffding Tree (ASHT) Bagging, we add an error change detector for each classifier. We test our improvements by performing an evaluation study on synthetic and real-world datasets comprising up to ten million examples

Pathways to folding, nucleation events and native geometry

We perform extensive Monte Carlo simulations of a lattice model and the Go potential to investigate the existence of folding pathways at the level of contact cluster formation for two native structures with markedly different geometries. Our analysis of folding pathways revealed a common underlying folding mechanism, based on nucleation phenomena, for both protein models. However, folding to the more complex geometry (i.e. that with more non-local contacts) is driven by a folding nucleus whose geometric traits more closely resemble those of the native fold. For this geometry folding is clearly a more cooperative process.Comment: Accepted in J. Chem. Phy

Recursos florestais não madeireiros: experiência e novos rumos em Rondônia.

Nesta publicação apresenta-se, de forma resumida, as principais pesquisas com Produtos Florestais Não Madeireiros (PFNM) realizadas pela Embrapa Rondônia e as novas tendências de aproveitamento da biodiversidade do Estado de Rondônia.bitstream/CPAF-RO-2010/14327/1/doc115-recursosflorestaisnaomadeireiros.pd

Fenotipagem associada a tolerância a seca em milho para uso em melhoramento, estudos genômicos e seleção assistida por marcadores.

bitstream/CNPMS/16487/1/Circ_39.pd