3,369 research outputs found
Geometries for universal quantum computation with matchgates
Matchgates are a group of two-qubit gates associated with free fermions. They
are classically simulatable if restricted to act between nearest neighbors on a
one-dimensional chain, but become universal for quantum computation with
longer-range interactions. We describe various alternative geometries with
nearest-neighbor interactions that result in universal quantum computation with
matchgates only, including subtle departures from the chain. Our results pave
the way for new quantum computer architectures that rely solely on the simple
interactions associated with matchgates.Comment: 6 pages, 4 figures. Updated version includes an appendix extending
one of the result
Discrete Wigner functions and quantum computational speedup
In [Phys. Rev. A 70, 062101 (2004)] Gibbons et al. defined a class of
discrete Wigner functions W to represent quantum states in a finite Hilbert
space dimension d. I characterize a set C_d of states having non-negative W
simultaneously in all definitions of W in this class. For d<6 I show C_d is the
convex hull of stabilizer states. This supports the conjecture that negativity
of W is necessary for exponential speedup in pure-state quantum computation.Comment: 7 pages, 2 figures, RevTeX. v2: clarified discussion on dynamics,
added refs., published versio
Spin-orbit mode transfer via a classical analog of quantum teleportation
We translate the quantum teleportation protocol into a sequence of coherent
operations involving three degrees of freedom of a classical laser beam. The
protocol, which we demonstrate experimentally, transfers the polarisation state
of the input beam to the transverse mode of the output beam. The role of
quantum entanglement is played by a non-separable mode describing the path and
transverse degrees of freedom. Our protocol illustrates the possibility of new
optical applications based on this intriguing classical analogue of quantum
entanglement.Comment: 5 pages, 7 figure
Entanglement and the nonlinear elastic behavior of forests of coiled carbon nanotubes
Helical or coiled nanostructures have been object of intense experimental and
theoretical studies due to their special electronic and mechanical properties.
Recently, it was experimentally reported that the dynamical response of
foamlike forest of coiled carbon nanotubes under mechanical impact exhibits a
nonlinear, non-Hertzian behavior, with no trace of plastic deformation. The
physical origin of this unusual behavior is not yet fully understood. In this
work, based on analytical models, we show that the entanglement among
neighboring coils in the superior part of the forest surface must be taken into
account for a full description of the strongly nonlinear behavior of the impact
response of a drop-ball onto a forest of coiled carbon nanotubes.Comment: 4 pages, 3 figure
Clinical and Pathological Findings in Women with Fabry Disease
Introduction. Fabry disease is a rare metabolic disorder caused by the genetic deficiency of the lysosomal hydrolase alpha-galactosidase A, located on chromosome X. Females with the defective gene are more than carriers and can develop a wide
range of symptoms. Nevertheless, disease symptoms generally occur later and are less severe in women than in men. The enzyme deficiency manifests as a glycosphingolipidosis with progressive
accumulation of glycosphingolipids and deposit of inclusion bodies in lysosomes giving a myelinlike appearance.
Patients and Methods. Records of renal biopsies performed on adults from 1st January 2008 to 31st August 2011, were retrospectively examined at the Renal Pathology Laboratory. We retrieved biopsies
diagnosed with Fabry disease and reviewed clinical and laboratory data and pathology findings.
Results. Four female patients with a mean age of 49.3±4.5 (44-55) years were identified. The mean proteinuria was 0.75±0.3 g/24h (0.4-1.2) and estimated
glomerular filtration rate (CKD EPI equation)
was 71±15.7 ml/min/1.73m2 (48-83). Three patients experienced extra-renal organ involvement (cerebrovascular, cardiac, dermatologic, ophthalmologic and
thyroid) with distinct severity degrees. Leukocyte α-GAL A activity was below normal range in the four cases but plasma and urinary enzymatic activity was normal.
Light microscopy showed predominant vacuolisation of the podocyte cytoplasm and darkly staining granular inclusions on paraffin and plastic-embedded semi-thin sections. Electron microscopy showed in
three patients the characteristic myelin-like inclusions in the podocyte cytoplasm and also focal podocyte foot process effacement. In one case the inclusions
were also present in parietal glomerular cells, endothelial cells of peritubular capillary and arterioles.
Conclusion. Clinical signs and symptoms are varied and can be severe among heterozygous females with Fabry disease. Intracellular accumulation of glycosphingolipids
is a characteristic histologic finding
of Fabry nephropathy. Since this disease is a potentially treatable condition, its early identification is imperative. We should consider it in the differential diagnosis of any patient presenting with proteinuria
and/or chronic kidney disease, especially if there is a family history of kidney disease
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