202 research outputs found
Training Recommendations from Early Childhood Education Providers
Early childcare education providers are seen as having many training needs. Training needs concur with the challenges most providers face, but not always. A series of focus groups conducted in Hancock County by Hanson (2017) provided an estimation of the resources present; the challenges early childcare providers faced; and the trainings that individuals would like to see. The school districts in the neighboring county, Washington County, were asked if the county was interested in having a similar audit. Washington County school districts declined suggesting that the county had all the services they needed. Instead this research was conducted to see if Washington County has all the resources it was preserved to have. When the research was conducted it was observed that there was striking similarities between the Hancock and Washington County studies in training and resource needs. Similar responses were collected about the perceived barriers and trainings recommendations that early childcare education providers would like to attend or have
The American Bar by Adolf Loos, Vienna, Austria 1907
The American Bar by Adolf Loos, inaugurated in Vienna in 1908, is a small watering hole, for ages frequented by the cultural intelligentsia of the city. Although reduced in space, it contains numerous architectural features, later developed by Loos in his oeuvre, establishing many tropes of modern architecture: the careful control of affects, the use of raw materials, the incorporation of advanced technical features. The text analyzes the numerous analogies and references that can be identified in this project within the canons of western architectur
Simultaneous accessory pathway and AV node mechanical block
We report a clinical case of a 22-year-old female referred to our institution due to palpitations
and preexcitation. Her ECG suggested a right superior paraseptal accessory pathway (AP),
which was localised during the electrophysiological study at the superior paraseptal region in
close proximity to the His recordings. Reproducible orthodromic reciprocating tachycardia
was induced by atrial pacing with extrastimuli. Cryo-mapping performed in the area of earliest
atrial activation was not able to terminate the tachycardia. A second attempt, slightly more
posterior, caused mechanical block of the AP, which rendered the tachycardia non-inducible.
More pressure with the ablation catheter determined a Wenckebach type supra-hisian AV
block, which was transient but reproducible. Given this finding no ablation was done.
Simultaneous block to the AP and the atrioventricular node has rarely been reported using
radiofrequency energy. However, to our knowledge this phenomenon has not been previously
reported in large series using cryo-thermal energ
Polyunsaturated fatty acids in atrial fibrillation: Looking for the proper candidates
This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionAtrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice
with growing prevalence in developed countries. Several medical and interventional
therapies, such as atrial specific drugs and pulmonary vein isolation, have demonstrated
prevention of recurrences. However, their suboptimal long-term success and significant
rate of secondary effects have led to intensive research in the last decade focused on
novel alternative and supplemental therapies. One such candidate is polyunsaturated fatty
acids (PUFAs). Because of their biological properties, safety, simplicity, and relatively cheap
cost, there is a special clinical interest in omega-3 PUFAs as a possible antiarrhythmic agent.
Obtained from diets rich in fish, they represent one of the current supplemental therapies.
At the cellular level, an increasing body of evidence has shown that n-3 PUFAs exert a
variety of effects on cardiac ion channels, membrane dynamic properties, inflammatory
cascade, and other targets related to AF prevention. In this article, we review the current
basic and clinical evidence pertinent to n-3 PUFAs in AF treatment and prevention.We also
discuss controversial outcomes among clinical studies and propose specific subsets of AF
patients who will benefit most from n-3 PUFAsNHLBI Grant K99-HL105574 to SFN and the Alfonso Martín Escudero Foundation Grant to DF
Hydrogen sulphide triggers VEGF-induced intracellular Ca2+ signals in human endothelial cells but not in their immature progenitors
Wound Repair Capability in EDS Fibroblasts can be Retrieved by Exogenous Type V Collagen
Impaired wound healing is a typical clinical hallmark of Ehlers-Danlos Syndrome (EDS). Mutated fibroblasts from EDS patients, which deposit an abnormal extracellular matrix, showed defective migration resulting in a marked delay in wound repair. The migratory capability remarkably improved in the presence of exogenous type V collagen
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