The Role of Osteopathic Care in Gynaecology and Obstetrics: An Updated Systematic Review

Background: Many efforts are made to find safer and more feasible therapeutic strategies to improve gynaecological care. Non-pharmacological treatments, such as osteopathic interventions, could be used as complementary strategies to better manage different gynaecological conditions. This review aims to report the effectiveness of osteopathic treatment in the gynaecology and obstetrics field, updating the previous review published in 2016. The secondary aim was to elucidate the role of somatic dysfunction (SD) in osteopathic assessment and treatment procedures, as well as their health and economic implications. Methods: An electronic search was conducted in the following databases: Embase, MEDLINE (PubMed), and Science direct. All types of clinical studies published between May 2014 and December 2021 have been included: randomised controlled trial (RCT), controlled before/after, interrupted time series quasi RCT, case controls, case reports, case series, observational, clinical studies involving any type of osteopathic treatment, (standardised, semi-standardised or patients’ need-based treatment) performed alone or in combination with other treatments, were included). Results: A total of 76,750 were identified through database searching and other sources. After the removal of duplicates, 47,655 papers were screened based on title and abstract. A total of 131 full-text articles were consequently assessed for eligibility. Twenty-one new articles were included in the synthesis. A total of 2632 participants with a mean age of 28.9 ± 10.5 years were included in the review. Conclusions: Results showed an effectiveness of osteopathic care in gynaecology and obstetrics, but the studies were too heterogeneous to perform quantitative analysis and make clinical recommendations. Nevertheless, osteopathic care could be considered a safe complementary approach to traditional gynaecological care

New data on wild grey mullet (mugil cephalus linnaeus, 1758) myxosporean (myxobolus episquamalis egusa et al., 1990) in the black sea

Flathead grey mullet, Mugil cephalus, with mass whitish cystlike plasmodia on their scales were collected at Kerchensky preglass of the Black Sea in 2015. The prevalence of infected fish varied from 15% in spring, reached 100% in summer, and declined to 2.5% in autumn. No fish mortality was detected. The spores were oval in frontal view, tapering to a blunt apex. Two unequal polar capsules were pyriform and extended over the anterior half of spore. Spores were 8.2\ub10.03 \u3bcm (7.9-8.4) long, 5.9\ub10.23 \u3bcm (5.2-7.3) wide, and 4.4\ub10.17 \u3bcm (4.0-4.7) thick. Two pyriform and unequal polar capsules were observed (4.0\ub10.07 \u3bcm (3.3-4.5) long, and 1.5\ub10.24 \u3bcm (1.1-1.8) wide). The investigation of nucleotide sequences of the 18S rDNA gene of the myxosporean spores from scales with universal primer A (5\u2032-ACCTGGTTGATCCTGCCAGT-3\u2032) and B (5\u2032-TGATCCTTCTGCAGGTTCACCTAC-3\u2032) showed 100% identity with episquamalis, and 99 % with M. bizerti, M. ichkeulensis, M. spinacurvata and Myxobolus sp. previously detected in mullets. The results obtained from the present study reveal that M. episquamalis, found on the scales of M. cephalus from Kerchensky preglass of the Black Sea, is new record for Russian waters

Quality and Safety of Beef Produced in Central African Sub-Region

Aim of this research is to provide a general situation of cattle slaughtered in Cameroon, as a representative example for the Central African Sub-region. The quality and safety of beef from the abattoir of Yaoundé, the largest in Cameroon, were considered. From January 2009 to March 2012, the pre-slaughter conditions and characteristics of 1953 cattle carcasses were recorded, as well as the pH of m. longissimus thoracis 24 h after slaughter. From these carcasses, 60 were selected to represent the bulls slaughtered. The quality parameters and composition of m. longissimus thoracis were carried out. The origin of most of the cattle was the Guinea High Savannah (74.6%), and transhumance was the common production system (75.5%). Gudali (45.6%), White Fulani (33.3%) and Red Mbororo (20.3%) breeds were predominant. Carcass weight was affected by rearing system and cattle category, and it markedly varied during year. Considering meat quality, the fat content was low (1.2%) and similar between breeds, moreover Gudali showed the toughest meat. Of the cows slaughtered, 27% were pregnant and the most common abnormal conditions encountered were ectoparasites, fatigue, lameness, fungal-like skin lesions, enlarged lymph nodes, respiratory distress, nodular lesions. More than 20% of the carcasses had some organs condemned, mainly for liver flukes (5.17%), and 1.0% of them were completely condemned due to tuberculosis, that also affected 3.28% of lungs. These data could aid authorities draw up programmes with the aim to strengthen cattle production, improve beef supply, control and prevent the observed diseases, and promote the regional trade

Eocene to Miocene Magnetostratigraphy, Biostratigraphy, and Chemostratigraphy at ODP Site 1090 (Sub-Antarctic South Atlantic)

At Ocean Drilling Program (ODP) Site 1090 (lat 42854.89S, long 8854.09E) locatedin a water depth of 3702 m on the Agulhas Ridge in the sub-Antarctic South Atlantic, ~300 m of middle Eocene to middle Miocenesediments were recovered with the advancedpiston corer (APC) and the extendedcore barrel (XCB). U-channel samplesfrom the 70–230 meters composite depth(mcd) interval provide a magnetic polaritystratigraphy that is extended to 380 mcd byshipboard whole-core and discrete sampledata. The magnetostratigraphy can be interpretedby the fit of the polarity-zone patternto the geomagnetic polarity time scale(GPTS) augmented by isotope data andbioevents with documented correlation tothe GPTS. Three normal-polarity subchrons(C5Dr.1n, C7Ar.1n, and C13r.1n),not included in the standard GPTS, are recordedat Site 1090. The base of the sampledsection is correlated to C19n (middleEocene), although the interpretation is unclearbeyond C17r. The top of the sampledsection is correlated to C5Cn (late earlyMiocene), although, in the uppermost 10 m of the sampled section, a foraminifer (Globorotaliasphericomiozea) usually associatedwith the Messinian and early Pliocene hasbeen identified. 87Sr/86Sr, d13C, and d18Ovalues measured on foraminifera, includingthe d18O and d13C shifts close to the Eocene/Oligocene boundary, support the correlationto the GPTS. For the interval spanningthe Oligocene/Miocene boundary, benthicd13C, d18O, and 87Sr/86Sr records from Site1090 can be correlated to isotope recordsfrom ODP Site 929 (Ceara Rise), providing support for the recently-published Oligocene/Miocene boundary age (22.92 Ma) of Shackleton et al

Statistical Mechanics of maximal independent sets

The graph theoretic concept of maximal independent set arises in several practical problems in computer science as well as in game theory. A maximal independent set is defined by the set of occupied nodes that satisfy some packing and covering constraints. It is known that finding minimum and maximum-density maximal independent sets are hard optimization problems. In this paper, we use cavity method of statistical physics and Monte Carlo simulations to study the corresponding constraint satisfaction problem on random graphs. We obtain the entropy of maximal independent sets within the replica symmetric and one-step replica symmetry breaking frameworks, shedding light on the metric structure of the landscape of solutions and suggesting a class of possible algorithms. This is of particular relevance for the application to the study of strategic interactions in social and economic networks, where maximal independent sets correspond to pure Nash equilibria of a graphical game of public goods allocation

Mental retardation in mucopolysaccharidoses correlates with high molecular weight urinary heparan sulphate derived glucosamine

none11noMucopolysaccharidoses (MPS) are characterized by mental retardation constantly present in the severe forms of Hurler (MPS I), Hunter (MPS II) and Sanfilippo (MPS III) diseases. On the contrary, mental retardation is absent in Morquio (MPS IV) and Maroteaux-Lamy (MPS VI) diseases and absent or only minimal in the attenuated forms of MPS I, II and III. Considering that MPS patients affected by mental disease accumulate heparan sulfate (HS) due to specific enzymatic defects, we hypothesized a possible correlation between urinary HS-derived glucosamine (GlcN) accumulated in tissues and excreted in biological fluids and mental retardation. 83 healthy subjects were found to excrete HS in the form of fragments due to the activity of catabolic enzymes that are absent or impaired in MPS patients. On the contrary, urinary HS in 44 patients was observed to be composed of high molecular weight polymer and fragments of various lengths depending on MPS types. On this basis we correlated mental retardation with GlcN belonging to high and low molecular weight HS. We demonstrate a positive relationship between the accumulation of high molecular weight HS and mental retardation in MPS severe compared to attenuated forms. This is also supported by the consideration that accumulation of other GAGs different from HS, as in MPS IV and MPS VI, and low molecular weight HS fragments do not impact on central nervous system disease.Coppa, G.V; Gabrielli, O.; Zampini, L.; Maccari, F.; Mantovani, V.; Galeazzi, T.; Santoro, L.; Padella, L.; Marchesiello, R.L.; Galeotti, F.; Volpi, N.Coppa, Giovanni Valentino; Gabrielli, Orazio; Zampini, Lucia; Maccari, F.; Mantovani, V.; Galeazzi, Tiziana; Santoro, Lucia; Padella, Lucia; Marchesiello, R. L.; Galeotti, F.; Volpi, N