5,754 research outputs found
Biomechanical comparison of the track start and the modified one-handed track start in competitive swimming: an intervention study
This study compared the conventional track and a new one-handed track start in elite age group swimmers to determine if the new technique had biomechanical implications on dive performance. Five male and seven female GB national qualifiers participated (mean ± SD:
age 16.7 ± 1.9 years, stretched stature 1.76 ± 0.8 m, body mass 67.4 ± 7.9 kg) and were assigned to a control group (n = 6) or an intervention group (n = 6) that learned the new onehanded dive technique. All swimmers underwent a 4-week intervention comprising 12 ± 3 thirty-minute training sessions. Video cameras synchronized with an audible signal and timing suite captured temporal and kinematic data. A
portable force plate and load cell handrail mounted to a swim starting block collected force data over 3 trials of each technique. A MANCOVA identified Block Time (BT),
Flight Time (FT), Peak Horizontal Force of the lower limbs (PHF) and Horizontal Velocity at Take-off (Vx) as covariates. During the 10-m swim trial, significant differences were found in Time to 10 m (TT10m), Total Time (TT), Peak Vertical Force (PVF), Flight Distance (FD), and Horizontal Velocity at Take-off (Vx) (p < .05). Results indicated that the conventional track start method was faster over 10 m, and therefore may be seen as a superior start after a short intervention. During training, swimmers and coaches should focus on the most statistically significant dive performance variables: peak horizontal force and velocity at take-off, block and flight time
Transferrin Binding to Peripheral Blood Lymphocytes Activated by Phytohemagglutinin Involves a Specific Receptor: Ligand Interaction
Immunohistological studies have indicated that membrane sites binding transferrin are present upon activated human peripheral blood lymphocytes. In this study, we have investigated transferrin uptake in human lymphocytes exposed to phytohemagglutinin (PHA), by quantitative radiobinding and immunofluorescence in parallel. In stimulated lymphocytes, binding was maximal after a 30-min incubation, being greatest at 37°C, and greater at 22°C than at 4°C. Although some shedding and endocytosis of transferrin occurred at 22° and 37°C, these factors, and resulting synthesis of new sites, did not affect measurement of binding which was found to be saturable, reversible, and specific for transferrin (Ka 0.5-2.5 x 10^8 M-1). Binding was greater after a 48-h exposure to PHA than after 24 h, and was maximal at 66 h. Sequential Scatchard analysis revealed no significant elevation in affinity of interaction. However, although the total number of receptors increased, the proportion of cells in which binding of ligand was detected immunohistologically increased in parallel, and after appropriate correction, the cellular density of receptors remained relatively constant throughout (60,000-80,000 sites/cell). Increments in binding during the culture period were thus due predominantly to expansion of a population of cells bearing receptors. Similar differences in binding were apparent upon comparison of cells cultured in different doses of PHA, and in unstimulated cells binding was negligible. Transferrin receptors appear, therefore, to be readily detectable only upon lymphocytes that have been activated
The Big Deal Is Dead! Long Live The Big Deal!
In many countries, the proclamation âThe King is dead, long live the Kingâ heralds the demise of the old monarch and the accession of a new one. This tradition ensures that the throne never remains empty while facilitating a smooth transition of power.
When the âBig Dealâ journal subscription model debuted in 1996, few suspected the extent to which academic libraries would come to rely upon it, or that it would become the primary channel by which academic libraries procure academic journal content.
As budget cuts take their toll on libraries, the demise of the Big Deal model seems inevitable as the true value of all-inclusive packages becomes less evident. But is it? Collection analysis reveals that many titles included within these âBig Dealâ packages remain unused or underutilized, significantly decreasing the overall value of serial subscription packages. SPARCâs Big Deal Cancellation Tracker shows an increasing number of libraries and consortia forgoing this model in favor of regaining local control over their collections and budgets.
The Binghamton University Libraries is no exception. Recent curriculum changes and financial developments have prompted us to adopt an ongoing evaluation of our usersâ information needs and proactively negotiate and cancel deals in order to better serve our constituents. This session described our fact finding, workflow modifications, and data analysis processes as well as the outcomes of our adventures in pursuing and planning for the cancellation of Big Deal agreements based on local collection development priorities and serials budget realities
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Rapid coastal deoxygenation due to ocean circulation shift in the NW Atlantic.
Global observations show that the ocean lost approximately 2% of its oxygen inventory over the last five decades 1-3, with important implications for marine ecosystems 4, 5. The rate of change varies with northwest Atlantic coastal waters showing a long-term drop 6, 7 that vastly outpaces the global and North Atlantic basin mean deoxygenation rates 5, 8. However, past work has been unable to resolve mechanisms of large-scale climate forcing from local processes. Here, we use hydrographic evidence to show a Labrador Current retreat is playing a key role in the deoxygenation on the northwest Atlantic shelf. A high-resolution global coupled climate-biogeochemistry model 9 reproduces the observed decline of saturation oxygen concentrations in the region, driven by a retreat of the equatorward-flowing Labrador Current and an associated shift toward more oxygen-poor subtropical waters on the shelf. The dynamical changes underlying the shift in shelf water properties are correlated with a slowdown in the simulated Atlantic Meridional Overturning Circulation 10. Our results provide strong evidence that a major, centennial-scale change of the Labrador Current is underway, and highlight the potential for ocean dynamics to impact coastal deoxygenation over the coming century
Electromagnetic modelling of a monolithic pulse reshaper based on a photonic crystal waveguide integrated with a SOA
More Discriminants with the Brezing-Weng Method
The Brezing-Weng method is a general framework to generate families of
pairing-friendly elliptic curves. Here, we introduce an improvement which can
be used to generate more curves with larger discriminants. Apart from the
number of curves this yields, it provides an easy way to avoid endomorphism
rings with small class number
A Device to Measure Magnetic and Mechanical Axis of Superconducting Magnets for the Large Hadron Collider at CERN
The LHC will be composed of 1232 horizontally curved, 15 meter long, cryodipoles and 474 Short Straight Sections, being assembled by different manufacturers. Magnetic axis alignment is an essential part of the magnets quality for two reasons: first, to be able to install correctly the magnets in the tunnel w.r.t. the reference beam orbit; secondly, to assess the relative alignment between the magnets composing the assembly, i.e. spool pieces for the dipoles and larger correctors for the SSS. A system called AC mole is being used extensively to measure magnetic and geometric axis, as well as roll angle, for every single magnet composing all the SSS. This paper describes its performance, its first years of operation, as well as the improvements that have made it very powerful, versatile and easy to use
Statistics for Fission-Track Thermochronology
This chapter introduces statistical tools to extract geologically meaningful information from fission-track (FT) data using both the external detector and LA-ICP-MS methods. The spontaneous fission of 238U is a Poisson process resulting in large single-grain age uncertainties. To overcome this imprecision, it is nearly always necessary to analyse multiple grains per sample. The degree to which the analytical uncertainties can explain the observed scatter of the single-grain data can be visually assessed on a radial plot and objectively quantified by a chi-square test. For sufficiently low values of the chi-square statistic (or sufficiently high p values), the pooled age of all the grains gives a suitable description of the underlying âtrueâ age population. Samples may fail the chi-square test for several reasons. A first possibility is that the true age population does not consist of a single discrete age component, but is characterised by a continuous range of ages. In this case, a ârandom effectsâ model can constrain the true age distribution using two parameters: the âcentral ageâ and the â(over)dispersionâ. A second reason why FT data sets might fail the chi-square test is if they are underlain by multimodal age distributions. Such distributions may consist of discrete age components, continuous age distributions, or a combination of the two. Formalised statistical tests such as chi-square can be useful in preventing overfitting of relatively small data sets. However, they should be used with caution when applied to large data sets (including length measurements) which generate sufficient statistical âpowerâ to reject any simple yet geologically plausible hypothesis
Additional Records of Deep-Sea Fishes from Off Greater New England
Recent review of deep-sea fishes captured deeper than 200m off greater New England, from the Scotian Shelf at 44°N to the southern New England Shelf at about 38°N, documented 591 species. Subsequent trawling activity and reviews of deep-sea taxa occurring in the area have revealed that an additional 40 species in habit the deep sea off New England. Thirty-two of these new records were captured in the course of 44 bottom trawls and 94 mid-water trawls over or in the proximity of Bear Seamount (39°55\u27N, 67°30\u27W). Five of the 40 species have been described as new to science, at least in part from material taken in the study area. In addition to describing such information as specimen size and position, depth, and date of capture, errors made in the previous study of deep-sea fishes in the area are identified and corrected
Combined radiolabel-binding and immunocytochemical evaluation of receptorâligand interactions. Studies of transferrin receptors on activated lymphocytes
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