35 research outputs found
Seismogenic faults, landslides, and associated tsunamis off southern Italy - Cruise No. M86/2, December 27, 2011 - January 17, 2012, Cartagena (Spain) - Brindisi (Italy)
Summary
The continental margins of southern Italy are located along converging plate boundaries, which
are affected by intense seismicity and volcanic activity. Most of the coastal areas experienced
severe earthquakes, landslides, and tsunamis in historical and/or modern times. The most
prominent example is the Messina earthquake of Dec. 28, 1908 (Ms=7.3; 80,000 casualties),
which was characterized by the worst tsunami Italy experienced in the historical time (~2000
casualties). It is, however, still unclear, whether this tsunami was triggered by a sudden vertical
movement along a major fault during the earthquake or as a result of a giant marine slide
initiated by the earthquake. The recurrence rates of major landslides and therefore the risk
associated with landslides is also unknown. Based on detailed bathymetric data sets collected by
Italian colleagues in the frame of the MaGIC Project (Marine Geohazards along the Italian
Coast), we collected seismic data (2D and 3D) and gravity cores in three working areas (The
Messina Straits, off Eastern Sicily, the Gioia Basin). A dense grid of new 2D-seismic data in the
Messina Straits will allow to map fault patterns in great detail. One interesting outcome in this
context is the identification of a set of normal faults striking in an EW-direction, which is almost
perpendicular to the previously postulated faults. This EW-striking faults seem to be active. The
area off eastern Sicily is characterized by numerous landslides and a complex deformation
pattern. A 3D-seismic data set has been collected during the cruise using the so called P-cable in
order to investigate these deformation patterns in detail. The new data will be the basis for a risk
assessment in the working areas
Clustering patients on the basis of their individual course of low back pain over a six month period
<p>Abstract</p> <p>Background</p> <p>Several researchers have searched for subgroups in the heterogeneous population of patients with non-specific low back pain (LBP). To date, subgroups have been identified based on psychological profiles and the variation of pain.</p> <p>Methods</p> <p>This multicentre prospective observational study explored the 6- month clinical course with measurements of bothersomeness that were collected from weekly text messages that were sent by 176 patients with LBP. A hierarchical cluster analysis, Ward's method, was used to cluster patients according to the development of their pain.</p> <p>Results</p> <p>Four clusters with distinctly different clinical courses were described and further validated against clinical baseline variables and outcomes. Cluster 1, a "stable" cluster, where the course was relatively unchanged over time, contained young patients with good self- rated health. Cluster 2, a group of "fast improvers" who were very bothered initially but rapidly improved, consisted of patients who rated their health as relatively poor but experienced the fewest number of days with bothersome pain of all the clusters. Cluster 3 was the "typical patient" group, with medium bothersomeness at baseline and an average improvement over the first 4-5 weeks. Finally, cluster 4 contained the "slow improvers", a group of patients who improved over 12 weeks. This group contained older individuals who had more LBP the previous year and who also experienced most days with bothersome pain of all the clusters.</p> <p>Conclusions</p> <p>It is possible to define clinically meaningful clusters of patients based on their individual course of LBP over time. Future research should aim to reproduce these clusters in different populations, add further clinical variables to distinguish the clusters and test different treatment strategies for them.</p
Adverse effects of extra-articular corticosteroid injections: a systematic review
<p>Abstract</p> <p>Background</p> <p>To estimate the occurrence and type of adverse effects after application of an extra-articular (soft tissue) corticosteroid injection.</p> <p>Methods</p> <p>A systematic review of the literature was made based on a PubMed and Embase search covering the period 1956 to January 2010. Case reports were included, as were prospective and retrospective studies that reported adverse events of corticosteroid injection. All clinical trials which used extra-articular corticosteroid injections were examined. We divided the reported adverse events into major (defined as those needing intervention or not disappearing) and minor ones (transient, not requiring intervention).</p> <p>Results</p> <p>The search yielded 87 relevant studies:44 case reports, 37 prospective studies and 6 retrospective studies. The major adverse events included osteomyelitis and protothecosis; one fatal necrotizing fasciitis; cellulitis and ecchymosis; tendon ruptures; atrophy of the plantar fat was described after injecting a neuroma; and local skin effects appeared as atrophy, hypopigmentation or as skin defect. The minor adverse events effects ranged from skin rash to flushing and disturbed menstrual pattern. Increased pain or steroid flare after injection was reported in 19 studies. After extra-articular injection, the incidence of major adverse events ranged from 0-5.8% and that of minor adverse events from 0-81%. It was not feasible to pool the risk for adverse effects due to heterogeneity of study populations and difference in interventions and variance in reporting.</p> <p>Conclusion</p> <p>In this literature review it was difficult to accurately quantify the incidence of adverse effects after extra-articular corticosteroid injection. The reported adverse events were relatively mild, although one fatal reaction was reported.</p
The effect of colchicine on systemic amyloidosis
[No abstract available
High dose intravenous methylprednisolone treatment in adult idiopathic thrombocytopenic purpura
[No abstract available
CIRCULATING IMMUNE-COMPLEXES IN SYSTEMIC AMYLOIDOSIS
WOS: A1981MF98300005PubMed ID: 7341031
Complex interactions fault fans developed in a strike-slip system: Kozan Fault Zone, Eastern Mediterranean Sea
Interpretation of high-resolution multichannel seismic reflection profiles shows that the Kozan Fault Zone is characterized by northeast-southwest-striking and mainly southeast-dipping planar faults which show significant normal-sense dip separations. Traced toward the southeast these faults progressively swing to assume an east-west trend along the northern margin of the Outer Cilicia Basin. The Kozan Fault Zone initially occupied a wide zone of distributed strike-slip translation in the Early Pliocene, but was subsequently concentrated into a narrowly focused strike-slip fault zone in the Late Pliocene and Quaternary. During the Late Pliocene, the Kozan Fault Zone propagated toward the southwest creating a restraining bend in the Cilicia Basin, and a new east-west oriented strike-slip fault (i.e., Silifke-Anamur Fault) in the Outer Cilicia Basin