Exclusive light particle measurements for the system 19^{19}F + 12^{12}C at 96 MeV

Decay sequence of hot {31}^P nucleus has been investigated through exclusive light charged particle measurements in coincidence with individual evaporation residues using the reaction {19}^F (96 MeV) + {12}^C. Information on the sequential decay chain have been extracted by confronting the data with the predictions of the statistical model. It is observed from the present analysis that such exclusive light charged particle data may be used as a powerful tool to probe the decay sequence of the hot light compound systems.Comment: 13 pages, 8 figures, Physical Review C (in press

Basic considerations in the dermatokinetics of topical formulations

Assessing the bioavailability of drug molecules at the site of action provides better insight into the efficiency of a dosage form. However, determining drug concentration in the skin layers following topical application of dermatological formulations is a great challenge. The protocols followed in oral formulations could not be applied for topical dosage forms. The regulatory agencies are considering several possible approaches such as tape stripping, microdialysis etc. On the other hand, the skin bioavailability assessment of xenobiotics is equally important for topical formulations in order to evaluate the toxicity. It is always possible that drug molecules applied on the skin surface may transport thorough the skin and reaches systemic circulation. Thus the real time measurement of molecules in the skin layer has become obligatory. In the last two decades, quite a few investigations have been carried out to assess the skin bioavailability and toxicity of topical/dermatological products. This review provides current understanding on the basics of dermatokinetics, drug depot formation, skin metabolism and clearance of drug molecules from the skin layers following application of topical formulations

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Not AvailableOn-farm experiments conducted at 60 locations in northern India demonstrated that yields and profits for rice and wheat increased significantly with a combined application of K, S and Zn along with farmer fertilisation practice that primarily focuses on N and P application. Application of Zn improved grain Zn contents in rice and wheat, which is critical for nutritional security in the region. Soil exchangeable and non-exchangeable K decreased without K application and increased with K application within just one rice-wheat cropping cycle.Not Availabl