A Summary of the Collaborative IS Curriculum Specification of the Joint DPMA, ACM, AIS Task Force

Information Systems \u2795 (IS \u2795), a model curriculum for a bachelor\u27s degree in Information Systems (IS), is the resulting development of collaborative work of a Joint Task Force of the Data Processing Management Association (DPMA), the Association for Computing Machinery (ACM), and Academy for Information Systems (AIS). Representation on the task force includes both academic and industrial members. This paper summarizes the full report (Figure 1). A definition of the IS discipline and its relevance within the business and university community is discussed. Resources needed to support a viable program are identified, including faculty, and information technology. Courses are identified and the characteristics of graduates defined. A paradigm is provided which couples a definition of the IS discipline and its underlying principles to the of characteristics of the IS graduate. An updated IS body of knowledge is presented. It is based on previous efforts of DPMA and ACM (Longenecker and Feinstein 1991a,b,c; Ashenhurst 1972; Couger 1972; ACM 1983 and ACM 1990; DPMA 1981, 1986). The current body of knowledge contains the Computer Science and Engineering body of knowledge (Turner and Tucker 1991). A cognitive behavioral metric is presented for specifying and evaluating depth of knowledge. The specification includes a numeric depth indicator and appropriate language to describe presentation goals and resultant behavior expected of students completing study of specific aspects of the curriculum. A modular concept of learning units is defined and utilized in specifying proposed courses. Methods for mapping the learning units to alternate course plans are discussed. Elements from the body of knowledge are combined in a logical top-down manner to form Learning Units (LU). Each LU contains a goal statement, behavioral objectives and associated elements from the body of knowledge. Five curriculum areas with 20 sub-areas form clusters of these learning units. A complete set of 128 learning units form meta-presentation units which can be organized in different schemes to meet individual institutional missions. One possible organization of these units into ten courses is presented. This paper provides curriculum guidelines for implementing undergraduate programs in information systems. The full report, IS\u2795, provides the detail necessary for design and implementation of courses. Dissemination of the curriculum and plans for review and updating the curriculum are presented

Il trattamento del gozzo immerso. La nostra esperienza

Gli Autori, dopo avere accennato alla storia naturale del gozzo immerso, riferiscono la loro esperienza di tale patologia maturata negli ultimi 5 anni, sottolineando i caratteri della complessa sintoma - tologia osservata nei vari casi, la condotta terapeutica seguìta, i buoni risultati ottenuti. Si soffermano quindi ad elencare le molteplici classificazioni, via via proposte. Illustrano le complesse situazioni sia di ordine emodina - mico che respiratorio di particolare interesse anestesiologico. Discutono, infine, sulla diagnostica e soprattutto sul corretto atteggiamento terapeutico il cui obiettivo è duplice: risolvere la sinto - matologia prodotta dalla massa mediastinica ed escludere la possibi - lità di recidiv

Biochemical and biophysical characterization of the major outer surface protein, OSP-A from North American and European isolates of Borrelia burgdorferi

Lyme borreliosis, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in North America and Western Europe. As the major delayed immune response in humans, a better understanding of the major outer surface lipoproteins OspA and OspB are of much interest. These proteins have been shown to exhibit three distinct phylogenetic genotypes based on their DNA sequences. This paper describes the cloning of genomic DNA for each variant and amplification of PCR. DNA sequence data was used to derive computer driven phylogenetic analysis and deduced amino acid sequences. Overproduction of variant OspAs was carried out in E. coli using a T7-based expression system. Circular dichroism and fluorescence studies was carried out on the recombinant B31 PspA yielding evidence supporting a B31 protein containing 11% alpha-helix, 34% antiparallel beta-sheet, 12% parallel beta sheet

SGR J1550-5418 bursts detected with the Fermi Gamma-ray Burst Monitor during its most prolific activity

We have performed detailed temporal and time-integrated spectral analysis of 286 bursts from SGR J1550-5418 detected with the Fermi Gamma-ray Burst Monitor (GBM) in January 2009, resulting in the largest uniform sample of temporal and spectral properties of SGR J1550-5418 bursts. We have used the combination of broadband and high time-resolution data provided with GBM to perform statistical studies for the source properties. We determine the durations, emission times, duty cycles and rise times for all bursts, and find that they are typical of SGR bursts. We explore various models in our spectral analysis, and conclude that the spectra of SGR J1550-5418 bursts in the 8-200 keV band are equally well described by optically thin thermal bremsstrahlung (OTTB), a power law with an exponential cutoff (Comptonized model), and two black-body functions (BB+BB). In the spectral fits with the Comptonized model we find a mean power-law index of -0.92, close to the OTTB index of -1. We show that there is an anti-correlation between the Comptonized Epeak and the burst fluence and average flux. For the BB+BB fits we find that the fluences and emission areas of the two blackbody functions are correlated. The low-temperature BB has an emission area comparable to the neutron star surface area, independent of the temperature, while the high-temperature blackbody has a much smaller area and shows an anti-correlation between emission area and temperature. We compare the properties of these bursts with bursts observed from other SGR sources during extreme activations, and discuss the implications of our results in the context of magnetar burst models.Comment: 13 pages, 10 figures, 2 tables; minor changes, ApJ in pres