Reducing meat consumption and following plant-based diets: current evidence and future directions to inform integrated transitions

Background: There is increasing consensus that transitioning towards reduced meat consumption and more plant-based diets is a key feature to address important health and sustainability challenges. However, relevant evidence that may inform these transitions remains fragmented with no overarching rationale or theoretical framework, which limits the ability to design and deliver coordinated efforts to address these challenges. Scope and approach: Eleven databases were systematically searched using sets of keywords referring meat curtailment, meat substitution and plant-based diets, as well as consumer choice, appraisal or behavior (2602 articles selected for title and abstract screening; 161 full-texts assessed for eligibility; 110 articles selected for extraction and coding). Barriers and enablers were identified and integrated into an overarching framework (i.e., COM-B system), which conceptualizes behavior as being influenced by three broad components: capability, opportunity and motivation. Key findings and conclusions: This review mapped potential barriers and enablers in terms of capability, opportunity, and motivation to reduce meat consumption and follow more plant-based diets. These included lack of information for consumers and difficulty to acquire new cooking skills (barrier, capability), changes in service provision in collective meal contexts (enabler, opportunity), and positive taste expectations for plant-based meals (enabler, motivation). Evidence on variables referring to the motivation domain is clearly increasing, but there is a striking need for studies that include capability and opportunity variables as well. The results of this review are relevant to a variety of fields and audiences interested in promoting sustainable living and health improvements through dietary choice.info:eu-repo/semantics/acceptedVersio

Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor

The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor. Furthermore, we recently reported that an alternative peptide, Ang-(1-9) also counteracts cardiac remodelling via the angiotensin type 2 receptor (AT(2)R). Here, we have engineered adenoviral vectors expressing fusion proteins which release Ang-(1-7) [RAdAng-(1-7)] or Ang-(1-9) [RAdAng-(1-9)] and compared their effects on cardiomyocyte hypertrophy in rat H9c2 cardiomyocytes or primary adult rabbit cardiomyocytes, stimulated with angiotensin II, isoproterenol or arg-vasopressin. RAdAng-(1-7) and RAdAng-(1-9) efficiently transduced cardiomyocytes, expressed fusion proteins and secreted peptides, as demonstrated by western immunoblotting and conditioned media assays. Furthermore, secreted Ang-(1-7) and Ang-(1-9) inhibited cardiomyocyte hypertrophy (Control = 168.7±8.4 µm; AngII = 232.1±10.7 µm; AngII+RAdAng-(1-7) = 186±9.1 µm, RAdAng-(1-9) = 180.5±9 µm; P<0.05) and these effects were selectively reversed by inhibitors of their cognate receptors, the mas antagonist A779 for RAdAng-(1-7) and the AT(2)R antagonist PD123,319 for RAdAng-(1-9). Thus gene transfer of Ang-(1-7) and Ang-(1-9) produces receptor-specific effects equivalent to those observed with addition of exogenous peptides. These data highlight that Ang-(1-7) and Ang-(1-9) can be expressed via gene transfer and inhibit cardiomyocyte hypertrophy via their respective receptors. This supports applications for this approach for sustained peptide delivery to study molecular effects and potential gene therapeutic actions

Distalização de molares superiores com mini implantes – caso clínico

Poster apresentado nas XXIII Jornadas Internacionais do ISCSEM, 20-21 Março de 2015, Egas Moniz, Caparica

Emphasizing the losses or the gains: comparing situational and individual moderators of framed messages to promote fruit and vegetable intake

Health messages are a commonly used way to promote changes in dietary habits but their efficacy could be enhanced by strategies such as the way in which the presented arguments are framed. This study aimed to test the effectiveness of framed messages (gain vs. loss) on behavioural intention and fruit and vegetable (FV) intake, comparing predictions based on prominent theoretical perspectives on message framing (function of the health behaviour and recipients' motivational orientation) and by further exploring the role of baseline intentions as a potential moderator of the framing effects. Undergraduate students (N = 180) completed the three assessment points in time. At baseline, individual moderators (motivational orientation and intentions) and fruit and vegetable intake were assessed. One week later, participants were randomly assigned to the loss or gain-framed message and indicated their intentions for FV intake the following week. A week later, FV intake over the previous week was assessed. The gain-frame was not conducive, per se, to higher intentions or behaviour. Having intention as the outcome, only baseline intentions moderated the effects of message frame. When considering FV intake as the outcome, both motivational orientation and baseline intentions moderated the effects of message frame, with the loss-frame promoting higher FV intake among individuals who were prevention-oriented and had higher baseline intentions. Findings suggest that the success of framed messages for FV intake depends upon the recipient's characteristics, such as motivational orientation, baseline intentions, and cultural background, with implications for health communication interventions.info:eu-repo/semantics/acceptedVersio

Estudo entre a maturação das vertebras cervicais e a idade cronológica

Poster apresentado na SPODF2015 - XXVII Reunião Científica Anual da Sociedade Portuguesa de Ortopedia Dento-Facial, 23-25 Abril de 2015, Figueira da Foz, Portugal

A brief intervention increases fruit and vegetable intake: a comparison of two intervention sequences

Background and Purpose: To evaluate the effectiveness of two subsequent intervention components (motivational and self-regulatory components), placed in different order, to promote fruit and vegetable (FV) intake. Methods: After baseline assessment, university students (N = 205, aged 18-26 years) were allocated to two groups. One group received a motivational intervention (outcome expectancies, risk perception, and task self-efficacy) followed by a self-regulatory intervention (planning and dietary self-efficacy) after 17 days. The second group received the same intervention conditions in the opposite order. Follow-up assessments were done after another 17 days. Results: Both intervention sequences yielded gains in terms of FV intake and self-efficacy. However, this gain was only due to the self-regulatory component whereas the motivational component did not contribute to the changes. Moreover, changes in intention and self-efficacy mediated between intervention sequence and follow-up behavior, suggesting that improving these proximal predictors of FV intake was responsible for the behavioral gains. Conclusions: Findings highlight the superiority of a self-regulatory intervention over a motivational intervention when it comes to dietary changes in this sample of young adults. Moreover, changes in dietary self-efficacy may drive nutritional changes.info:eu-repo/semantics/publishedVersio

Reassessment of exclusion zones of GM cotton in Brazil: the case of Rondônia State.

Cotton (Gossypium hirsutum) was the second crop to received commercial approval to planting GM cultivars in Brazil, in 2005. At that time, the main concern was the possibility of gene flow from GM cottons to affect in situ maintenance of others species sexually compatible ? G. barbadense and G. mustelinum. To avoid this problem, the National Biosafety Technical Commision (CTNBio) conditioned the cultivation of GM cotton to the creation of GM Cotton Exclusion Zones, where just non-GM cultivars could be planted. Cotton cultivation is an important agricultural activity in Brazil and the producers are almost unanimous: fields of GM cultivars yield more, the management is less laborious and the protection against weeds and pests is higher. For these reasons, farmers in the Rondonia, a state included into the exclusion zones, requested CTNBio to remove Rondônia from the exclusion zones. To deliberate, CTNBio asked Embrapa for information. To properly answer, an expedition was performed in 20 of the state?s 52 municipalities, and only one species was found, Gossypium barbadense. Plants were present just in higly anthropized areas, mainly in dooryards of urban and rural houses, and they were maintained as medicinal plants. Plants of G. barbadense were found in 5% to 10% of the houses, protected from gene flow by walls, houses, and trees. There was no signal of interespecifc crossing, even in municipalities were conventional Gossypium hirsutum were planted. The main risk to in situ mainatenance of G. barbadense is the loss of cultural habits resulting from the expansion of the public health care, which increases the use of chemical drugs over medicinal plants. In conclusion, gene flow is not a significant concern to the preservation of Gossypium barbadense in Rondônia, and there is no reason for the state to remain as an exclusion zones