1,307 research outputs found
Regulations Overshadow Science in Ohio’s Educational Standards - Opinion
Ohio Academy of Scienc
Science and Technology Policy Issues of Concern to Ohio's Leaders: A Report of the Science Policy Advisory Committee of the The Ohio Academy of Science
Author Institution: Science Policy Advisory Committee, The Ohio Academy of ScienceBiotechnology, education reform, environmental protection, technology development, and cancer prevention were the leading science and technology policy issues most on the minds of Ohio's leaders at the end of 2000 according to a mail-response survey by The Ohio Academy of Science. Biotechnology received the greatest number of mentions (9) out of 108 specific issues identified by 38 respondents who identified up to five science and technology policy issues. The survey audience included legislators, professional organizations, registered lobbyists, university presidents, corporate vice presidents for R&D, regulatory agency directors, state and local elected officials, and environmental groups. The results of this survey will serve the Academy's continuing effort to provide informed scientific advice to Ohio
Orientation filtering by growth-velocity competition in zone-melting recrystallization of silicon on SiO_2
We describe a method of controlling the in-plane directions of grains in (100)-textured silicon films produced by zone-melting recrystallization over amorphous SiO2. Grains having in-plane orientation within a narrow range are able to grow through an orientation filter consisting of a pattern of crystallization barriers, while grains having other orientations are occluded. The results of experiments using an orientation filter, and the parameters which optimize filter performance, are reported
16 x 25 Ge:Ga Detector Arrays for FIFI LS
We are developing two-dimensional 16 x 25 pixel detector arrays of both
unstressed and stressed Ge:Ga photoconductive detectors for far-infrared
astronomy from SOFIA. The arrays, based on earlier 5 x 5 detector arrays used
on the KAO, will be for our new instrument, the Far Infrared Field Imaging Line
Spectrometer (FIFI LS). The unstressed Ge:Ga detector array will cover the
wavelength range from 40 to 120 microns, and the stressed Ge:Ga detector array
from 120 to 210 microns. The detector arrays will be operated with multiplexed
integrating amplifiers with cryogenic readout electronics located close to the
detector arrays. The design of the stressed detector array and results of
current measurements on several prototype 16 pixel linear arrays are reported.
They demonstrate the feasibility of the current concept. ***This paper does not
include Figures due to astro-ph size limitations. Please download entire file
at http://fifi-ls.mpe-garching.mpg.de/spie.det.ps.gz ***Comment: 8 pages, SPIE Proceedings, Astronomical Telescopes and
Instrumentation 200
Stressed detector arrays for airborne astronomy
The development of stressed Ge:Ga detector arrays for far-infrared astronomy from the Kuiper Airborne Observatory (KAO) is discussed. Researchers successfully constructed and used a three channel detector array on five flights from the KAO, and have conducted laboratory tests of a two-dimensional, 25 elements (5x5) detector array. Each element of the three element array performs as well as the researchers' best single channel detector, as do the tested elements of the 25 channel system. Some of the exciting new science possible with far-infrared detector arrays is also discussed
The 158 micron (CII) mapping of galaxies: Probing the atomic medium
Using the MPE/UCB Far-infrared Imaging Fabry-Perot Interferometer (FIFI) on the Kuiper Airborne Observatory (KAO), we have made large scale maps of (CII) in the spiral galaxies NGC 6946, NGC 891, M83 and the peculiar elliptical Cen A, thus allowing for the first time, detailed studies of the spatial distribution of the FIR line emission in external galaxies. We find that the (CII) emission comes from a mixture of components of interstellar gas. The brightest emission is associated with the nuclear regions, a second component traces the spiral arms as seen in the nearly face on spiral galaxies NGC 6946 and M83 and the largest star forming/H2 regions contained within them, and another extended component of low brightness can be detected in all of the galaxies far from the nucleus, beyond the extent of CO emission
The effects of star formation on the low-metallicity ISM: NGC4214 mapped with Herschel/PACS spectroscopy
We present Herschel/PACS spectroscopic maps of the dwarf galaxy NC4214
observed in 6 far infrared fine-structure lines: [C II] 158mu, [O III] 88mu, [O
I] 63mu, [O I] 146mu, [N II] 122mu, and [N II] 205mu. The maps are sampled to
the full telescope spatial resolution and reveal unprecedented detail on ~ 150
pc size scales. We detect [C II] emission over the whole mapped area, [O III]
being the most luminous FIR line. The ratio of [O III]/[C II] peaks at about 2
toward the sites of massive star formation, higher than ratios seen in dusty
starburst galaxies. The [C II]/CO ratios are 20 000 to 70 000 toward the 2
massive clusters, which are at least an order of magnitude larger than spiral
or dusty starbursts, and cannot be reconciled with single-slab PDR models.
Toward the 2 massive star-forming regions, we find that L[CII] is 0.5 to 0.8%
of the LTIR . All of the lines together contribute up to 2% of LTIR . These
extreme findings are a consequence of the lower metallicity and young,
massive-star formation commonly found in dwarf galaxies. These conditions
promote large-scale photodissociation into the molecular reservoir, which is
evident in the FIR line ratios. This illustrates the necessity to move to
multiphase models applicable to star-forming clusters or galaxies as a whole.Comment: Accepted for publication in the A&A Herschel Special Issu
Process development for improved Car-t production utilizing an automated perfusion stirred-tank bioreactor
Ex vivo genetically-modified cellular immunotherapies, such as chimeric antigen receptor T-cells (CAR-T), have generated significant clinical and commercial outcomes due to their unparalleled response rates against refractory/relapsed blood cancers. However, the development and manufacture of these advanced therapies face a number of translational bottlenecks that must be addressed to ensure long-term commercial viability.
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