71 research outputs found

    Gdal-On

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    Tc-99m labeled red blood cells scintigraphy: a diagnostic method for orbital cavernous hemangioma INTRODUCTION Tc-99m labeled red blood cells (Tc-99m RBC) is an intravascular tracer which has been used extensively in nuclear medicine (1). The main applications of the tracer are: the evaluation of the cardiovascular system (2), and the detection of gastrointestinal bleeding (3). It has also been found to be specific for diagnosing cavernous hemangioma of the liver (4). Encouraged by this high specificity of Tc-99m RBC for diagnosing cavernous hemangioma of the liver, as early as 1982 we attempted to use this intravascular tracer for diagnosing orbital cavernous hemangioma (5). We used Tc-99m RBC scintigraphy to establish the preoperative diagnosis of orbital cavernous hemangioma in 3 patients with orbital masses, in whom the diagnosis of orbital cavernous hemangioma was suspected on CT scan. The preoperative diagnosis of all 3 patients was later confirmed pathologically. From then onwards, over the past 16 years, we have used Tc-99m RBC scintigraphy routinely to confirm the diagnosis of orbital cavernous hemangioma whenever it was suspected on CT scan. Following our initial work, 3 cases of orbital cavernous hemangioma which were diagnosed by nuclear medicine techniques using red blood cells were recently published (6,7 ). The purpose of this retrospective case series was to evaluate Tc-99m RBC scintigraphy as a diagnostic method for orbital cavernous hemangioma. ABSTRACT

    High performance computation of landscape genomic models including local indicators of spatial association

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    With the increasing availability of both molecular and topo-climatic data, the main challenges facing landscape genomics – that is the combination of landscape ecology with population genomics – include processing large numbers of models and distinguishing between selection and demographic processes (e.g. population structure). Several methods address the latter, either by estimating a null model of population history or by simultaneously inferring environmental and demographic effects. Here we present samβada, an approach designed to study signatures of local adaptation, with special emphasis on high performance computing of large-scale genetic and environmental data sets. samβada identifies candidate loci using genotype–environment associations while also incorporating multivariate analyses to assess the effect of many environmental predictor variables. This enables the inclusion of explanatory variables representing population structure into the models to lower the occurrences of spurious genotype–environment associations. In addition, samβada calculates local indicators of spatial association for candidate loci to provide information on whether similar genotypes tend to cluster in space, which constitutes a useful indication of the possible kinship between individuals. To test the usefulness of this approach, we carried out a simulation study and analysed a data set from Ugandan cattle to detect signatures of local adaptation with samβada, bayenv, lfmm and an FST outlier method (FDIST approach in arlequin) and compare their results. samβada – an open source software for Windows, Linux and Mac OS X available at http://lasig.epfl.ch/sambada – outperforms other approaches and better suits whole-genome sequence data processing

    Petite suite en style ancienne

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    4 p. 31 cm. Prélude.--Sarabande.--Menuet

    Famous Musicians of a Wandering Race [title page]

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    http://cdm16613.contentdm.oclc.org/cdm/singleitem/collection/p16613coll1/id/15/rec/1Title page of "Famous Musicians of a Wandering Race" autographed by Gdal Saleski and presented to the Friedheim Music Library of the Peabody Institute

    Elègie

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    score and part. 34 cm
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