All conformally flat pure radiation metrics

The complete class of conformally flat, pure radiation metrics is given, generalising the metric recently given by Wils.Comment: 7 pages, plain Te

Topological Hysteresis in the Intermediate State of Type-I Superconductors

Magneto-optical imaging of thick stress-free lead samples reveals two distinct topologies of the intermediate state. Flux tubes are formed upon magnetic field penetration (closed topology) and laminar patterns appear upon flux exit (open topology). Two-dimensional distributions of shielding currents were obtained by applying an efficient inversion scheme. Quantitative analysis of the magnetic induction distribution and correlation with magnetization measurements indicate that observed topological differences between the two phases are responsible for experimentally observable magnetic hysteresis.Comment: 4 pages, RevTex

Origins of Sinuous and Braided Channels on Ascraeus Mons, Mars - A Keck Geology Consortium Undergraduate Research Project

Water has clearly played an important part in the geological evolution of Mars. There are many features on Mars that were almost certainly formed by fluvial processes -- for example, the channels Kasei Valles and Ares Vallis in the Chryse Planitia area of Mars are almost certainly fluvial features. On the other hand, there are many channel features that are much more difficult to interpret -- and have been variously attributed to volcanic and fluvial processes. Clearly unraveling the details of the role of water on Mars is extremely important, especially in the context of the search of extinct or extant life. In this project we built on our recent work in determining the origin of one channel on the southwest rift apron of Ascraeus Mons. This project, funded by the Keck Geology Consortium and involving 4 undergraduate geology majors took advantage of the recently available datasets to map and analyze similar features on Ascraeus Mons and some other areas of Mars. A clearer understanding of how these particular channel features formed might lead to the development of better criteria to distinguish how other Martian channel features formed. Ultimately this might provide us with a better understanding of the role of volcanic and fluvial processes in the geological evolution of Mars

Thermomechanical relaxation and different water states in cottonseed protein derived bioplastics

Thermomechanical relaxation events and different water states in cottonseed protein bioplastics are presented whilst investigating the effects of aldehyde cross-linking agents. Thermomechanical relaxation of cottonseed protein bioplastics associated with protein denaturation, moisture absorption and broad glass transitions (Tg) were observed from DSC and DMA measurements. It was shown that variation of the aldehyde influences the storage modulus at very low temperature (below Tg). From measurements of the water fusion point, enthalpy, vaporisation, and weight loss, three water states in the water-absorbed bioplastics are suggested; namely strongly-bound-to-polymer, weakly-bound-to-polymer and bulk-like water. The water content and unreacted cross-linking agents are influential factors in controlling formation of the different water states, whilst the selection of different aldehydes was found to be negligible. These results could be valuable for adjusting the thermomechanical relaxations of protein based bioplastics, and tailoring their properties in wet environments

Development and application of optical fibre strain and pressure sensors for in-flight measurements

Fibre optic based sensors are becoming increasingly viable as replacements for traditional flight test sensors. Here we present laboratory, wind tunnel and flight test results of fibre Bragg gratings (FBG) used to measure surface strain and an extrinsic fibre Fabry–Perot interferometric (EFFPI) sensor used to measure unsteady pressure. The calibrated full scale resolution and bandwidth of the FBG and EFFPI sensors were shown to be 0.29% at 2.5 kHz up to 600 με and 0.15% at up to 10 kHz respectively up to 400 Pa. The wind tunnel tests, completed on a 30% scale model, allowed the EFFPI sensor to be developed before incorporation with the FBG system into a Bulldog aerobatic light aircraft. The aircraft was modified and certified based on Certification Standards 23 (CS-23) and flight tested with steady and dynamic manoeuvres. Aerobatic dynamic manoeuvres were performed in flight including a spin over a g-range −1g to +4g and demonstrated both the FBG and the EFFPI instruments to have sufficient resolution to analyse the wing strain and fuselage unsteady pressure characteristics. The steady manoeuvres from the EFFPI sensor matched the wind tunnel data to within experimental error while comparisons of the flight test and wind tunnel EFFPI results with a Kulite pressure sensor showed significant discrepancies between the two sets of data, greater than experimental error. This issue is discussed further in the paper

Role for polo-like kinase 4 in mediation of cytokinesis.

The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes. In addition, we find that phospho-PLK4 (pPLK4) is cleaved and distributed to kinetochores (metaphase and anaphase), spindle midzone/cleavage furrow (anaphase and telophase), and midbody (cytokinesis) during cell division in immortalized epithelial cells as well as breast, ovarian, and colorectal cancer cells. The distribution of pPLK4 midzone/cleavage furrow and midbody positions pPLK4 to play a functional role in cytokinesis. Indeed, we found that inhibition of PLK4 kinase activity with a small-molecule inhibitor, CFI-400945, prevents translocation to the spindle midzone/cleavage furrow and prevents cellular abscission, leading to the generation of cells with polyploidy, increased numbers of duplicated centrosomes, and vulnerability to anaphase or mitotic catastrophe. The regulatory role of PLK4 in cytokinesis makes it a potential target for therapeutic intervention in appropriately selected cancers

Formation of submarine lava channel textures : insights from laboratory simulations

Author Posting. © American Geophysical Union, 2006. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 111 (2006): B03104, doi:10.1029/2005JB003796.Laboratory simulations using polyethylene glycol (PEG) extruded at a constant rate and temperature into a tank with a uniform basal slope and filled with a cold sucrose solution generate channels that are defined by stationary levees and mobile flow interiors. These laboratory channels consistently display the following surface textures in the channel: smooth, folded, lineated, and chaotic. In the simulations, we can observe specific local conditions including flow rate, position within the channel, and time that combine to develop each texture. The textures in PEG flows form due to relative differences in shear forces between the PEG crust and the underlying liquid wax. Minimal shear forces form smooth crust, whereas folded crust forms when the shear is sufficiently high to cause ductile deformation. Brittle deformation of solid PEG creates a chaotic texture, and lineated crust results from shear forces along the channel-levee margin. We observe similar textures in submarine lava channels with sources at or near the Axial Summit Trough of the East Pacific Rise between 9° and 10°N. We mapped the surface textures of nine submarine lava channels using high-resolution digital images collected during camera tows. These textural maps, along with observations of the formation of similar features in analog flows, reveal important information about the mechanisms occurring across the channel during emplacement, including relative flow velocity and shear stress.The cruise was funded by a grant to WHOI from the National Science Foundation (NSF) OCE-9819261, with additional funding provided by WHOI thorough the Vetlesen Foundation. The PEG experiments were funded by NSF OCE-0425073 in a grant to Tracy Gregg

The influence of patellar tendon and muscle-tendon unit stiffness on quadriceps explosive strength in man

What is the central question of this study? \ud Do tendon and/or muscle–tendon unit stiffness influence rate of torque development? What is the main finding and its importance? In our experimental conditions, some measures of relative (to maximal voluntary torque and tissue length) muscle–tendon unit stiffness had small correlations with voluntary/evoked rate of torque development over matching torque increments. However, absolute and relative tendon stiffness were unrelated to voluntary and evoked rate of torque development. Therefore, the muscle aponeurosis but not free tendon influences the relative rate of torque development. Factors other than tissue stiffness more strongly determine the absolute rate of torque development. The influence of musculotendinous tissue stiffness on contractile rate of torque development (RTD) remains opaque. In this study, we examined the relationships between both patellar tendon (PT) and vastus lateralis muscle–tendon unit (MTU) stiffness and the voluntary and evoked knee-extension RTD. Fifty-two healthy untrained men completed duplicate laboratory sessions. Absolute and relative RTD were measured at 50 N m or 25% maximal voluntary torque (MVT) increments from onset and sequentially during explosive voluntary and evoked octet isometric contractions (supramaximal stimulation; eight pulses at 300 Hz). Isometric MVT was also assessed. Patellar tendon and MTU stiffness were derived from simultaneous force and ultrasound recordings of the PT and vastus lateralis aponeurosis during constant RTD ramp contractions. Absolute and relative (to MVT and resting tissue length) stiffness (k) was measured over identical torque increments as RTD. Pearson's correlations tested relationships between stiffness and RTD measurements over matching absolute/relative torque increments. Absolute and relative PT k were unrelated to equivalent voluntary/evoked (r = 0.020–0.255, P = 0.069–0.891). Absolute MTU k was unrelated to voluntary or evoked RTD (r ≤ 0.191, P ≥ 0.184), but some measures of relative MTU k were related to relative voluntary/evoked RTD (e.g. RTD for 25–50% MVT, r = 0.374/0.353, P = 0.007/0.014). In conclusion, relative MTU k explained a small proportion of the variance in relative voluntary and evoked RTD (both ≤19%), despite no association of absolute MTU k or absolute/relative PT k with equivalent RTD measures. Therefore, the muscle-aponeurosis component but not free tendon was associated with relative RTD, although it seems that an overriding influence of MVT negated any relationship of absolute MTU k and absolute RTD