Follajes comercializados en dos mercados de flores del altiplano central mexicano

Los tradicionales mercados de flores Xochiquetzal del municipio de Tenancingo, Estado de México y Jamaica en el Distrito Federal, son importantes en la comercialización de especies de follajes, de los cuales se desconoce su filiación taxonómica, por lo que resulta relevante realizar su inventario. Para ello, se visitaron ambos mercados para la adquisición de las especies, y su posterior herborización e identificación taxonómica en el herbario de la facultad de Ciencias Agrícolas de la Universidad Autónoma del Estado de México. Adicionalmente se obtuvo información complementaria de cada una de ellas a través de encuestas aplicadas. Con los datos obtenidos se realizó el inventario y el catálogo de follajes de ambos mercados.Los resultados obtenidos muestran que el número de especies comercializadas en los dos mercados es de 87 especies, las cuales pertenecen a 57 géneros y 38 familias. El mayor número de especies de follajes se comercializan en forma de manojo (43%) y el menor número corresponde a racimos de frutos (3%); el mayor número de especies de follajes se comercializan en el mercado de Jamaica (71%) y sólo el 13% en el mercado de Tenancingo. La familia Araceae muestra un mayor número de especies de follajes (10%). Estos datos se deben a que sus especies tienen inflorescencias muy llamativas y que tienen una larga vida en florero. La información recopilada en el catálogo servirá de difusión y apoyo para establecer estrategias de conservación y uso sustentable de las especies comercializadas en los mercados, objeto de estudio

Local collaborations for physical activity promotion: a network analysis.

This study aims to describe a local network for physical activity promotion and identify factors associated to collaboration or partnership ties between its actors. The study was carried out in a district of São Paulo, Brazil. Thirty-two actors responsible for policies, programs, and initiatives to promote physical activity within the district were interviewed from June to December 2012. Interviews included information about the actors' attributes and their relationships with the other actors. Network analysis techniques were used to describe and analyze the structure of the network. Thirty-two actors maintained 179 relationships among themselves (density = 0.18), of which 46% were reciprocal. Four in 10 relationships did not extend beyond information exchange. Forty-six relationships were classified as collaborations or partnerships (density = 0.09), of which 40% were concentrated on one actor of the public sector. To perceive institutional structure and bureaucracy as limiting factors to networking has been positively associated with new collaboration or partnership ties (OR = 2.37; 95%CI: 1.2-5.50). Understanding the structure of the network may empower the actors and foster self-management, facilitating the identification and decision, in a collaborative way, in which new relationships may have greater impact in the physical activity promotion within the district

Cocaine Induced QT Prolongation

Introduction:The Q-T interval represents ventricular repolarization of the heart. Prolongation of this interval is called Long QT syndrome (LQTS) and can lead to deadly arrythmias such as Torsades de Pointes. (1) According to the AHA, a Q-T interval is prolonged when it is \u3e450ms in males and \u3e460ms in females. LQTS has different etiologies (not limited to, but including): idiopathic, congenital, electrolyte abnormalities, and drug-induced. (2) However, recreational drugs such as cocaine may often be overlooked by some. A study by Magnano et al. found that cocaine can increase a QTc interval by 23 points (+/- 25) (P Case Presentation: 42-year-old gentleman with a known history of hypertension not on medications and polysubstance abuse who presented to the ED with complaints of fever, hypertension, sore throat, nausea, bilateral upper and lower extremity joint pains and stiffness and was admitted for sepsis due to influenza. Patient was taking ibuprofen and acetaminophen since the symptoms started. UDS was positive for cocaine, cannabinoids and opioids. EKG on admission was remarkable for sinus tachycardia with qtc of 472. While on the hospital his blood pressure remained persistently elevated with systolic blood pressure in the 200s after nifedipine and hydralazine were administered at the ED. Enalapril injection 1.25 mg q6h PRN was commenced but patient\u27s blood pressure remained elevated with systolic blood pressure in the 200s. Patient blood pressure continued to be elevated regarding treatment; therefore, patient was transferred to the ICU for the management of hypertensive urgency with Cardizem drip. EKG on the second day showed sinus tachycardia with qtc 452. No medication that affects the qtc were given or taken by the patient that are known to cause qtc prolongation except for cocaine. Conclusion: Cocaine use has been associated with QTc prolongation, which can increase the risk of serious cardiac arrhythmias. Cocaine can interfere with the normal functioning of ion channels in the heart, leading to disruptions in the electrical signals. This disturbance can prolong the QTc interval, potentially causing torsades de pointes or other arrhythmias. Prolongation of the QTc interval can lead to an increased risk of this abnormal heart rhythm, which may result in fainting, seizures, or even sudden cardiac death. Healthcare providers need this information to make informed decisions about prescribing medications, avoiding potentially harmful drug interactions, and ensuring patient safety. It\u27s crucial for healthcare professionals to be aware of these risks when treating individuals who use or have a history of cocaine use, as it can impact decisions regarding medication and overall patient care

Oesophageal cancer mortality in Spain: a spatial analysis

BACKGROUND: Oesophageal carcinoma is one of the most common cancers worldwide. Its incidence and mortality rates show a wide geographical variation at a world and regional level. Geographic mapping of age-standardized, cause-specific death rates at a municipal level could be a helpful and powerful tool for providing clues leading to a better understanding of its aetiology. METHODS: This study sought to describe the geographic distribution of oesophageal cancer mortality for Spain's 8077 towns, using the autoregressive spatial model proposed by Besag, York and Mollié. Maps were plotted, depicting standardised mortality ratios, smoothed relative risk (RR) estimates, and the spatial pattern of the posterior probability of RR being greater than 1. RESULTS: Important differences associated with area of residence were observed in risk of dying from oesophageal cancer in Spain during the study period (1989-1998). Among men, excess risk appeared across the north of the country, along a band spanning the length of the Cantabrian coastline, Navarre, the north of Castile & León and the north-west of La Rioja. Excess risk was likewise observed in the provinces of Cadiz and part of Seville in Andalusia, the islands of Tenerife and Gran Canaria, and some towns in the Barcelona and Gerona areas. Among women, there was a noteworthy absence of risk along the mid-section of the Cantabrian seaboard, and increases in mortality, not observed for men, in the west of Extremadura and south-east of Andalusia. CONCLUSION: These major gender- and area-related geographical differences in risk would seem to reflect differences in the prevalence of some well-established and modifiable risk factors, including smoking, alcohol consumption, obesity and diet. In addition, excess risks were in evidence for both sexes in some areas, possibly suggesting the implication of certain local environmental or socio-cultural factors. From a public health standpoint, small-area studies could be very useful for identifying locations where epidemiological research and intervention measures ought to receive priority, given the potential for reducing risk in certain places.This study was funded by Grant No. EPY-1176/02 from the Carlos III Institute of Health (ISCIII) and RCESP FIS-C03/09 (Spanish Network for Cooperative Research in Epidemiology and Public Health)S

Childhood leukaemia risk and residential proximity to busy roads

BACKGROUND: Current evidence suggests that childhood leukaemia can be associated with residential traffic exposure; nevertheless, more results are needed to support this conclusion. OBJECTIVES: To ascertain the possible effects of residential proximity to road traffic on childhood leukaemia, taking into account traffic density, road proximity and the type of leukaemia (acute lymphoid leukaemia or acute myeloid leukaemia). METHODS: We conducted a population-based case-control study of childhood leukaemia in Spain, covering the period 1990-2011. It included 1061 incidence cases gathered from the Spanish National Childhood Cancer Registry and those Autonomous Regions with 100% coverage, and 6447 controls, individually matched by year of birth, sex and autonomous region of residence. Distances were computed from the respective participant's residential locations to the different types of roads and four different buffers. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (95%CIs), were calculated for four different categories of distance to roads. RESULTS: Cases of childhood leukaemia had more than three-fold increased odds of living at <50 m of the busiest motorways compared to controls (OR = 2.90; 95%CI = 1.30-6.49). The estimates for acute lymphoid leukaemia (ALL) were slightly higher (OR = 2.95; 95%CI = 1.22-7.14), while estimates for cases with the same address at birth and at diagnosis were lower (OR = 2.40; 95%CI = 0.70-8.30). CONCLUSIONS: Our study agrees with the literature and furnishes some evidence that living near a busy motorway could be a risk factor for childhood leukaemia.This study was funded by Spain's Health Research Fund, Spain (Fondo de Investigación Sanitaria - FIS 12/01416 and FIS CP11/00112), Carlos III Health Institute, Spain Grand EPY 1344/16 and Scientific Foundation of the Spanish Association Against Cancer, Spain (Fundación Científica de la Asociación Española Contra el Cáncer (AECC) – EVP-1178/14). This article presents independent research. The views expressed are those of the authors and not necessarily those of the Carlos III Institute of Health.S

Radiopharmacokinetics and uptake of 99m Tc-cRGD in av B3 integrins for imaging angiogenesis in induced malignant tumors in athymic mice

The multistep process of angiogenesis offers several targets for therapeutic interventions. One molecular target structure is the alfa five beta three (av b3 ) integrin which is expressed on vascular endothelial cells and over-expressed in cancer tumor angiogenesis. To image neoangiogenesis in athymic mice with induced pancreatic, breast and prostate malignant tumors a new radiopharmaceutical was developed. The 99mTc-EDDA/HYNIC-cyclic-Arg-Gly- Asp-D-Phe-Lys (99mTc-cRGD) targets integrin receptors av b3 and was prepared with an average radiochemical purity > 95 %. 99mTc-cRGD shows high in vivo stability, fast blood clearance and rapid renal excretion in mice. There are statistical differences between tumor/muscle ratios for the 3 tumors studied. The highest tumor/non-target ratio was found in breast cancer (7.2 after 24 h) and a representative dorsal SPECT image was obtained where the tumor showed up very clearly over the background tissue. The high resolution of the image implies that 99mTc-cRGD will be of great value in nuclear medicine as a potential radiopharmaceutical for av b3 integrins receptor uptake and for imaging neoangiogenesis in neoplastic tissue and to follow up cancer tumor progression

Childhood leukemia and residential proximity to industrial and urban sites

BACKGROUND: Few risk factors for the childhood leukemia are well established. While a small fraction of cases of childhood leukemia might be partially attributable to some diseases or ionizing radiation exposure, the role of industrial and urban pollution also needs to be assessed. OBJECTIVES: To ascertain the possible effect of residential proximity to both industrial and urban areas on childhood leukemia, taking into account industrial groups and toxic substances released. METHODS: We conducted a population-based case-control study of childhood leukemia in Spain, covering 638 incident cases gathered from the Spanish Registry of Childhood Tumors and for those Autonomous Regions with 100% coverage (period 1990-2011), and 13,188 controls, individually matched by year of birth, sex, and autonomous region of residence. Distances were computed from the respective subject's residences to the 1068 industries and the 157 urban areas with ≥10,000 inhabitants, located in the study area. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (95%CIs) for categories of distance to industrial and urban pollution sources were calculated, with adjustment for matching variables. RESULTS: Excess risk of childhood leukemia was observed for children living near (≤2.5 km) industries (OR=1.31; 95%CI=1.03-1.67) - particularly glass and mineral fibers (OR=2.42; 95%CI=1.49-3.92), surface treatment using organic solvents (OR=1.87; 95%CI=1.24-2.83), galvanization (OR=1.86; 95%CI=1.07-3.21), production and processing of metals (OR=1.69; 95%CI=1.22-2.34), and surface treatment of metals (OR=1.62; 95%CI=1.22-2.15) - , and urban areas (OR=1.36; 95%CI=1.02-1.80). CONCLUSIONS: Our study furnishes some evidence that living in the proximity of industrial and urban sites may be a risk factor for childhood leukemia.This study was funded by Spain’s Health Research Fund (Fondode Investigación Sanitaria–FIS 12/01416 and FIS CP11/00112).S

Exploring Blue Spaces' Effects on Childhood Leukaemia Incidence: A Population-Based Case-Control Study in Spain

Background: Blue spaces have been a key part of human evolution, providing resources and helping economies develop. To date, no studies have been carried out to explore how they may be linked to paediatric oncological diseases. Objectives: To explore the possible relationship of residential proximity to natural and urban blue spaces on childhood leukaemia. Methods: A population-based case–control study was conducted in four regions of Spain across the period 2000–2018. A total of 936 incident cases and 5616 controls were included, individually matched by sex, year of birth and place of residence. An exposure proxy with four distances (250 m, 500 m, 750 m, and 1 km) to blue spaces was built using the geographical coordinates of the participants’ home residences. Odds ratios (ORs) and 95% confidence intervals (95%CIs) for blue-space exposure were calculated for overall childhood leukaemia, and the acute lymphoblastic (ALL) and acute myeloblastic leukaemia (AML) subtypes, with adjustment for socio-demographic and environmental covariates. Results: A decrease in overall childhood leukaemia and ALL-subtype incidence was found as we came nearer to children’s places of residence, showing, for the study as a whole, a reduced incidence at 250 m (odds ratio (OR) = 0.77; 95%CI = 0.60–0.97), 500 m (OR = 0.78; 95%CI = 0.65–0.93), 750 m (OR = 0.80; 95%CI = 0.69–0.93), and 1000 m (OR = 0.84; 95%CI = 0.72–0.97). AML model results showed an increasing incidence at closest to subjects’ homes (OR at 250m = 1.06; 95%CI=0.63–1.71). Conclusions: Our results suggest a possible association between lower childhood leukaemia incidence and blue-space proximity. This study is a first approach to blue spaces’ possible effects on childhood leukaemia incidence; consequently, it is necessary to continue studying these spaces—while taking into account more individualised data and other possible environmental risk factors.This study was funded by Carlos III Institute of Health, Spain (grant numbers PI19CIII/00025, PI16CIII/00009, EPY-505/19-PFIS), and Spain’s Health Research Fund (Fondo de Investigación Sanitaria-FIS grant number 12/01416). The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.S

Justo para ti” Campaña Publicitaria para el Seguro Pago por Kilómetros de Rimac 2021

En el presente trabajo se explica la campaña publicitaria “Justo para ti” propuesta para Rimac sobre el Seguro Pago por Kilómetros, un seguro vehicular creado en un contexto en el cual los autos son menos utilizados y los hábitos y costumbres de los consumidores han cambiado a raíz de la pandemia en Lima Metropolitana. Por ello, se realiza una investigación exploratoria con metodología cualitativa con el objetivo de identificar por qué los consumidores no consideran relevante la adquisición de seguros vehiculares actualmente. En esta, se identifica que el público objetivo siente que el seguro es justo por diversos motivos frente a sus competidores. A raíz de ello, se crea una campaña que mantiene esa esencia de lo que significa el término “justo” para ellos y demuestra la empatía de la marca frente a estos nuevos estilos de vida mediante un personaje que comprende sus nuevas necesidades. Adicionalmente, se resalta el beneficio principal del producto, que es el precio al cual calificamos también como justo, pues se pretende pagar, únicamente, por los kilómetros consumidos. Esta campaña pretende impulsar la venta del Seguro Pago por Kilómetros tanto en antiguos como en nuevos clientes demostrando que este seguro vehicular se adapta al estilo de vida de sus clientes brindándoles un servicio y precio justos