Optimising trotter-suzuki decompositions for quantum simulation using evolutionary strategies

One of the most promising applications of near-term quantum computing is the simulation of quantum systems, a classically intractable task. Quantum simulation requires computationally expensive matrix exponentiation; Trotter-Suzuki decomposition of this exponentiation enables efficient simulation to a desired accuracy on a quantum computer. We apply the Covariance Matrix Adaptation Evolutionary Strategy (CMA-ES) algorithm to optimise the Trotter-Suzuki decompositions of a canonical quantum system, the Heisenberg Chain; we reduce simulation error by around 60%. We introduce this problem to the computational search community, show that an evolutionary optimisation approach is robust across runs and problem instances, and find that optimisation results generalise to the simulation of larger systems

A study of salmonid egg and fry survival in the River Taff catchment

This report looks at previous findings that egg survival was related to the percentage of fine solids in the spawning gravels of the River Taff. Green salmonid eggs were planted out at 8 sites in the Taff catchment; and eyed salmonid eggs were planted out at 27 sites. Gravel cores were taken at 18 of these sites and an analysis of their composition was carried out, particular attention being given to the pecentage of particles less than 1mm. As well as its method, the report includes its own findings and recommendations, which includes other factors influencing egg survival such as the need for water quality improvements

Systematic review of economic evaluations and cost analyses of guideline implementation strategies

Objectives To appraise the quality of economic studies undertaken as part of evaluations of guideline implementation strategies; determine their resources use; and recommend methods to improve future studies. Methods Systematic review of economic studies undertaken alongside robust study designs of clinical guideline implementation strategies published (1966-1998). Studies assessed against the BMJ economic evaluations guidelines for each stage of the guideline process (guideline development, implementation and treatment). Results 235 studies were identified, 63 reported some information on cost. Only 3 studies provided evidence that their guideline was effective and efficient. 38 reported the treatment costs only, 12 implementation and treatment costs, 11 implementation costs alone, and two guideline development, implementation and treatment costs. No study gave reasonably complete information on costs. Conclusions Very few satisfactory economic evaluations of guideline implementation strategies have been performed. Current evaluations have numerous methodological defects and rarely consider all relevant costs and benefits. Future evaluations should focus on evaluating the implementation of evidence based guidelines. Keywords: Cost-effectiveness analysis, physician (or health care professional) behaviour, practice guidelines, quality improvement, systematic review.Peer reviewedAuthor versio

Slope dynamics project report : Holderness Coast - Aldbrough, survey & monitoring, 2001-2013

This report is a published product of an ongoing study by the British Geological Survey (BGS) of the coastal change at Aldbrough on the Holderness coast, East Riding of Yorkshire, UK. The test site at Aldbrough has been selected as one of the BGS Landslide Observatories because it is representative of the high rates of coastal recession along this stretch of the east coast. The Aldbrough Landslide Observatory is operated under the BGS ‘Slope Dynamics’ task within the BGS’s ‘Landslide’ project of the ‘Shallow Geohazards and Risk’ team. As well as providing new insights with respect to the volumetric rates of recession and the near surface processes, it is a focus for the trialling of new surface and subsurface monitoring technologies. The establishment of the Aldbrough observatory and the initial research findings are reported in a series of reports in addition to this report. These are: Hobbs, P.R.N., Jones, L.D., & Kirkham, M.P. (2015) Slope Dynamics project report: Holderness Coast – Aldbrough: Drilling & Instrumentation, 2012-2015. British Geological Survey, Internal Report No IR/15/001. Hobbs, P.R.N., Kirkham, M.P. & Morgan, D.J.R. (2016) Geotechnical laboratory testing of glacial deposits from Aldbrough, Phase 2 boreholes. British Geological Survey, Open Report No. OR/15/056. Whilst this report is focused on the survey and monitoring programme, it should be read in conjunction with the reports listed above, which provide further details on drilling and instrumentation and the geotechnical properties of the underlying geology. A series of reports will follow presenting the updated survey and monitoring reports, and their publication will be announced through the BGS project web page. Readers of these reports will probably also be interested in the context for this research, which can be found in: Hobbs, P.R.N., Pennington, C.V.L., Pearson, S.G., Jones, L.D., Foster, C., Lee, J.R., Gibson, A. (2008) Slope Dynamics Project Report: the Norfolk Coast (2000-2006). British Geological Survey, Open Report No. OR/08/018

Possible origins of macroscopic left-right asymmetry in organisms

I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules. In light of a fundamental symmetry principle, the typical pattern-formation mechanisms of diffusion plus regulation cannot implement the "right-hand rule"; at the microscopic level, the cell's cytoskeleton of chiral filaments seems always to be involved, usually in collective states driven by polymerization forces or molecular motors. It seems particularly easy for handedness to emerge in a shear or rotation in the background of an effectively two-dimensional system, such as the cell membrane or a layer of cells, as this requires no pre-existing axis apart from the layer normal. I detail a scenario involving actin/myosin layers in snails and in C. elegans, and also one about the microtubule layer in plant cells. I also survey the other examples that I am aware of, such as the emergence of handedness such as the emergence of handedness in neurons, in eukaryote cell motility, and in non-flagellated bacteria.Comment: 42 pages, 6 figures, resubmitted to J. Stat. Phys. special issue. Major rewrite, rearranged sections/subsections, new Fig 3 + 6, new physics in Sec 2.4 and 3.4.1, added Sec 5 and subsections of Sec

The Large Scale Structure in the Universe: From Power-Laws to Acoustic Peaks

The most popular tools for analysing the large scale distribution of galaxies are second-order spatial statistics such as the two-point correlation function or its Fourier transform, the power spectrum. In this review, we explain how our knowledge of cosmic structures, encapsulated by these statistical descriptors, has evolved since their first use when applied on the early galaxy catalogues to the present generation of wide and deep redshift surveys, incorporating the most challenging discovery in the study of the galaxy distribution: the detection of Baryon Acoustic Oscillations.Comment: 20 pages, 12 figures, to appear in "Data Analysis in Cosmology", Lecture Notes in Physics, 2008, eds. V. J. Martinez, E. Saar, E. Martinez-Gonzalez, and M.J. Pons-Borderia, Springer-Verla

Establishing tephrostratigraphic frameworks to aid the study of abrupt climatic and glacial transitions: a case study of the Last Glacial-Interglacial Transition in the British Isles (c. 16-8 ka BP)

Distally dispersed tephra layers have become an important tool in the investigation of palaeoenvironmental and archaeological records across the globe. They offer possibilities for the synchronisation and improved chronological control in those records to which they can be traced and hence contribute to an improved understanding of the pattern and timing of environmental and archaeological change during periods of rapid climatic adjustment. However, their use as robust isochronous markers for synchronising records is frequently compromised by uncertainties relating to stratigraphical context, precise chronology and chemical composition. Here we collate and review the tephrostratigraphical information dating to the Last Glacial-Interglacial Transition (LGIT; c. 16-8 ka BP) in the British Isles based on published and unpublished records obtained from 54 sites. Based on details of their stratigraphic position, chronology and chemical composition, we propose that 26 individual eruption events may be represented in this collective record which spans the LGIT. The great majority of these eruptives can be traced in origin to Iceland, but we also report on the recent discoveries of ultra-distal tephra from the North American Cascades range, including for the first time the Mount St Helens J Tephra at a site in southern Ireland. These particular ultra-distal discoveries have resulted from a reinterpretation of older data, demonstrating the potential importance of ‘unknown’ analyses in older tephra datasets. The outcome of this review is a comprehensive but provisional tephrostratigraphic framework for the LGIT in the British Isles, which helps to focus future research on parts of the scheme that are in need of further development or testing. The results, therefore, make an important contribution to the wider European tephrostratigraphic framework, while adding new discoveries of transcontinental isochronous tephra markers