Climate Change in Queensland's Grazing Lands. I. Approaches and Climatic Trends

Climate change is an important global issue but is yet to be recognised as such by many rangelands users. This paper reviews some of the uncertainties relating to pre-instrumental and future climate change and documents current trends and fluctuations in climate of Queensland's grazing lands. Analysis of daily climate surfaces for Queensland's pastoral/cropping zone shows high variability in annual rainfall which is influenced by the El NiHo-Southern Oscillation (ENSO) phenomenon. This relationship, when examined using moving windows, has changed during this century with the 1930-40s being a period of low correlation. Minimum temperatures taken from the climate surfaces also changed, showing a significant (P<0.01) increase over time especially in May. Over the 40 years since 1957, annual minimum temperatures have increased by l.0°C for the pastoral/cropping zone and coastal sub-zone, winter minimum temperatures by 1.2°C for the pastoral/cropping zone (1.3°C for the coastal sub-zone), summer minimum temperatures by 0.7°C for the pastoral/cropping zone and coastal sub-zone, and May minimum temperatures by 2.8°C for the pastoral/cropping zone (3.0°C for the coastal sub-zone). Consistent significant trends in vapour pressure (increasing, P<0.001) and solar radiation (decreasing, P<0.05) also occurred in May. The mechanisms for the identified climate trends and unusual behaviour of ENS0 are the subject of speculation with attribution of causes to natural variability or the enhanced greenhouse effect being unresolved. Continued monitoring of these trends and fluctuations will be important for the future management of Queensland's grazing lands with this analysis highlighting the need for discrimination of trends from natural variability. In terms of grazing management and degradation processes, this work also highlights that general changes in climate averages may disguise important variation at yearly and decadal time scales

Hopping motion of lattice gases through nonsymmetric potentials under strong bias conditions

The hopping motion of lattice gases through potentials without mirror-reflection symmetry is investigated under various bias conditions. The model of 2 particles on a ring with 4 sites is solved explicitly; the resulting current in a sawtooth potential is discussed. The current of lattice gases in extended systems consisting of periodic repetitions of segments with sawtooth potentials is studied for different concentrations and values of the bias. Rectification effects are observed, similar to the single-particle case. A mean-field approximation for the current in the case of strong bias acting against the highest barriers in the system is made and compared with numerical simulations. The particle-vacancy symmetry of the model is discussed.Comment: 8 pages (incl. 6 eps figures); RevTeX 3.

Holomorphic Factorization for a Quantum Tetrahedron

We provide a holomorphic description of the Hilbert space H(j_1,..,j_n) of SU(2)-invariant tensors (intertwiners) and establish a holomorphically factorized formula for the decomposition of identity in H(j_1,..,j_n). Interestingly, the integration kernel that appears in the decomposition formula turns out to be the n-point function of bulk/boundary dualities of string theory. Our results provide a new interpretation for this quantity as being, in the limit of large conformal dimensions, the exponential of the Kahler potential of the symplectic manifold whose quantization gives H(j_1,..,j_n). For the case n=4, the symplectic manifold in question has the interpretation of the space of "shapes" of a geometric tetrahedron with fixed face areas, and our results provide a description for the quantum tetrahedron in terms of holomorphic coherent states. We describe how the holomorphic intertwiners are related to the usual real ones by computing their overlap. The semi-classical analysis of these overlap coefficients in the case of large spins allows us to obtain an explicit relation between the real and holomorphic description of the space of shapes of the tetrahedron. Our results are of direct relevance for the subjects of loop quantum gravity and spin foams, but also add an interesting new twist to the story of the bulk/boundary correspondence.Comment: 45 pages; published versio

UK bone conduction hearing device consensus workshop:narrative summary

Objectives : To identify United Kingdom (UK)-specific research priorities in the field of bone conduction hearing devices (BCHDs). Method : Narrative summary of the discussions and outcomes of a UK BCHD research workshop. The workshop was organized on 8 September 2016 under the auspices of the National Institute for Health Research (NIHR) Clinical Research Network (CRN) ENT Specialty group and Royal College of Surgeons (RCS) Clinical Research Initiative. Representatives from a wide range of patient and professional groups from the UK and abroad were invited to attend. Main outcome measures were research priorities and approaches in the field of BCHDs. Results : Key research questions in the field of BCHDs are as follows: (1) What are the existing national BCHD practices? (2) What are the patient information and support needs on BCHDs? (3) Which outcomes should be measured across clinical studies in the field of BCHDs? The workshop suggested the following approaches to address these priorities: (1) a service evaluation of current UK BCHD practice; development of a national registry of BCHDs; (2) qualitative research to understand patient information and support needs; development of patient decision support tools; (3) development of core outcome sets for BCHDs. Discussion : Building upon the framework of the recent UK Research Agenda for ENT, Hearing and Balance, patients and professionals defined key UK-specific research priorities and approaches in the field of BCHDs. This approach promotes engagement, buy-in, national collaboration and thereby value of future BCHD research

Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains

Intestinal carriage of extended-spectrum beta-lactamase (ESBL) -producing bacteria in food-producing animals and contamination of retail meat may contribute to increased incidences of infections with ESBL-producing bacteria in humans. Therefore, distribution of ESBL genes, plasmids and strain genotypes in Escherichia coli obtained from poultry and retail chicken meat in the Netherlands was determined and defined as ‘poultry-associated’ (PA). Subsequently, the proportion of E. coli isolates with PA ESBL genes, plasmids and strains was quantified in a representative sample of clinical isolates. The E. coli were derived from 98 retail chicken meat samples, a prevalence survey among poultry, and 516 human clinical samples from 31 laboratories collected during a 3-month period in 2009. Isolates were analysed using an ESBL-specific microarray, sequencing of ESBL genes, PCR-based replicon typing of plasmids, plasmid multi-locus sequence typing (pMLST) and strain genotyping (MLST). Six ESBL genes were defined as PA (blaCTX-M-1, blaCTX-M-2, blaSHV-2, blaSHV-12, blaTEM-20, blaTEM-52): 35% of the human isolates contained PA ESBL genes and 19% contained PA ESBL genes located on IncI1 plasmids that were genetically indistinguishable from those obtained from poultry (meat). Of these ESBL genes, 86% were blaCTX-M-1 and blaTEM-52 genes, which were also the predominant genes in poultry (78%) and retail chicken meat (75%). Of the retail meat samples, 94% contained ESBL-producing isolates of which 39% belonged to E. coli genotypes also present in human samples. These findings are suggestive for transmission of ESBL genes, plasmids and E. coli isolates from poultry to humans, most likely through the food chain

Climate Change in Queensland's Grazing Lands: II. An Assessment of the Impact on Animal Production From Native Pastures

The 160 million ha of grazing land in Queensland support approximately 10 million beef equivalents (9.8 million cattle and 10.7 million sheep) with treed and cleared native pastures as the major forage source. The complexity of these biophysical systems and their interaction with pasture and stock management, economic and social forces limits our ability to easily calculate the impact of climate change scenarios. We report the application of a systems approach in simulating the flow of plant dry matter and utilisation of forage by animals. Our review of available models highlighted the lack of suitable mechanistic models and the potential role of simple empirical relationships of utilisation and animal production derived from climatic and soil indices. Plausible climate change scenarios were evaluated by using a factorial of rainfall (f 10%) * 3260C temperature increase * doubling CO, in sensitivity studies at property, regional and State scales. Simulation of beef cattle liveweight gain at three locations in the Queensland black speargrass zone showed that a *lo% change in rainfall was magnified to be a f 15% change in animal production (liveweight gain per ha) depending on location, temperature and CO, change. Models of 'safe' carrying capacity were developed from property data and expert opinion. Climate change impacts on 'safe' carrying capacity varied considerably across the State depending on whether moisture, temperature or nutrients were the limiting factors. Without the effect of doubling CO,, warmer temperatures and +lo% changes in rainfall resulted in -35 to +70% changes in 'safe' carrying capacity depending on location. With the effect of doubling CO, included, the changes in 'safe' carrying capacity ranged from -12 to +115% across scenarios and locations. When aggregated to a whole-of-State carrying capacity, the combined effects of warmer temperature, doubling CO, and +lo% changes in rainfall resulted in 'safe' carrying capacity changes of +3 to +45% depending on rainfall scenario and location. A major finding of the sensitivity study was the potential importance of doubling CO, in mitigating or amplifying the effects of warmer temperatures and changes in rainfall. Field studies on the impact of CO, are therefore a high research priority. Keywords: climate change, Queensland, simulation, rangelands, beef production, cattle, carrying capacity, CO,, utilisatio

CEO pay, shareholder returns, and accounting profits

We assess the impact on CEO pay (including salary, cash bonus, and benefits in kind) of changes in both accounting and shareholder returns in 99 British companies in the years 1972-89. After correcting for heterogeneity biases inherent in the standard specifications of the problem, we find a strong positive relationship between CEO pay and within-company changes in shareholder returns, and no statistically significant relationship between CEO pay and within-company changes in accounting returns. Differences between firms in long-term average profitability do appear to have a substantial effect on CEO pay, while differences between firms in shareholder returns add nothing to the within-firm pay dynamics.These findings call into question the rationale for explicitly share-based incentive schemes

Multi-centre evaluation of a phenotypic extended spectrum β-lactamase detection guideline in the routine setting

AbstractThis study aimed to evaluate the routine setting performance of a guideline for phenotypic detection of extended spectrum β-lactamases (ESBLs) in Enterobacteriaceae, recommending ESBL confirmation with Etest or combination disc for isolates with a positive ESBL screen test (i.e. cefotaxime and/or ceftazidime MIC >1 mg/L or an automated system ESBL warning). Twenty laboratories submitted 443 Enterobacteriaceae with a positive ESBL screen test and their confirmation test result (74% Escherichia coli, 12% Enterobacter cloacae, 8% Klebsiella pneumoniae, 3% Proteus mirabilis, 2% Klebsiella oxytoca). Presence of ESBL genes was used as reference test. Accuracy of local phenotypic ESBL detection was 88%. The positive predictive value (PPV) of local screen tests was 70%, and differed per method (Vitek-2: 69%, Phoenix: 68%, disc diffusion: 92%), and species (95% K. pneumoniae-27% K. oxytoca). A low PPV (3%) was observed for isolates with automated system alarm but third-generation cephalosporin MICs <2 mg/L. Local ESBL confirmation had a PPV and negative predictive value (NPV) of 93% and 90%, respectively. Compared with centrally performed confirmation tests, 7% of local tests were misinterpreted. Combination disc was more specific than Etest (91% versus 61%). Confirmation tests were not reliable for P. mirabilis and K. oxytoca (PPV 33% and 38%, respectively, although NPVs were 100%). In conclusion, performance of Etests could be enhanced by education of technicians to improve their interpretation, by genotypic ESBL confirmation of P. mirabilis and K. oxytoca isolates with positive phenotypic ESBL confirmation, and by interpreting isolates with a positive ESBL alarm but an MIC <2 mg/L for cefotaxime and ceftazidime as ESBL-negative

Heart-Kidney Interaction: Epidemiology of Cardiorenal Syndromes

Cardiac and kidney diseases are common, increasingly encountered, and often coexist. Recently, the Acute Dialysis Quality Initiative (ADQI) Working Group convened a consensus conference to develop a classification scheme for the CRS and for five discrete subtypes. These CRS subtypes likely share pathophysiologic mechanisms, however, also have distinguishing clinical features, in terms of precipitating events, risk identification, natural history, and outcomes. Knowledge of the epidemiology of heart-kidney interaction stratified by the proposed CRS subtypes is increasingly important for understanding the overall burden of disease for each CRS subtype, along with associated morbidity, mortality, and health resource utilization. Likewise, an understanding of the epidemiology of CRS is necessary for characterizing whether there exists important knowledge gaps and to aid in the design of clinical studies. This paper will provide a summary of the epidemiology of the cardiorenal syndrome and its subtypes

Detecting local synchronization in coupled chaotic systems

We introduce a technique to detect and quantify local functional dependencies between coupled chaotic systems. The method estimates the fraction of locally syncronized configurations, in a pair of signals with an arbitrary state of global syncronization. Application to a pair of interacting Rossler oscillators shows that our method is capable to quantify the number of dynamical configurations where a local prediction task is possible, also in absence of global synchronization features