37 research outputs found
Planck scale effects in neutrino physics
We study the phenomenology and cosmology of the Majoron (flavon) models of
three active and one inert neutrino paying special attention to the possible
(almost) conserved generalization of the Zeldovich-Konopinski-Mahmoud lepton
charge. Using Planck scale physics effects which provide the breaking of the
lepton charge, we show how in this picture one can incorporate the solutions to
some of the central issues in neutrino physics such as the solar and
atmospheric neutrino puzzles, dark matter and a 17 keV neutrino. These
gravitational effects induce tiny Majorana mass terms for neutrinos and
considerable masses for flavons. The cosmological demand for the sufficiently
fast decay of flavons implies a lower limit on the electron neutrino mass in
the range of 0.1-1 eV.Comment: 24 pages, 1 figure (not included but available upon request), LaTex,
IC/92/196, SISSA-140/92/EP, LMU-09/9
A class-wide phylogenetic assessment of Dothideomycetes
We present a comprehensive phylogeny derived from 5 genes, nucSSU, nucLSU
rDNA, TEF1, RPB1 and RPB2, for 356 isolates and 41
families (six newly described in this volume) in Dothideomycetes. All
currently accepted orders in the class are represented for the first time in
addition to numerous previously unplaced lineages. Subclass
Pleosporomycetidae is expanded to include the aquatic order
Jahnulales. An ancestral reconstruction of basic nutritional modes
supports numerous transitions from saprobic life histories to plant associated
and lichenised modes and a transition from terrestrial to aquatic habitats are
confirmed. Finally, a genomic comparison of 6 dothideomycete genomes with
other fungi finds a high level of unique protein associated with the class,
supporting its delineation as a separate taxon
A class-wide phylogenetic assessment of Dothideomycetes
We present a comprehensive phylogeny derived from 5 genes, nucSSU, nucLSU rDNA, TEF1, RPB1 and RPB2, for 356 isolates and 41 families (six newly described in this volume) in Dothideomycetes. All currently accepted orders in the class are represented for the first time in addition to numerous previously unplaced lineages. Subclass Pleosporomycetidae is expanded to include the aquatic order Jahnulales. An ancestral reconstruction of basic nutritional modes supports numerous transitions from saprobic life histories to plant associated and lichenised modes and a transition from terrestrial to aquatic habitats are confirmed. Finally, a genomic comparison of 6 dothideomycete genomes with other fungi finds a high level of unique protein associated with the class, supporting its delineation as a separate taxon
Vascular Remodeling in Health and Disease
The term vascular remodeling is commonly used to define the structural changes in blood vessel geometry that occur in response to long-term physiologic alterations in blood flow or in response to vessel wall injury brought about by trauma or underlying cardiovascular diseases.1, 2, 3, 4 The process of remodeling, which begins as an adaptive response to long-term hemodynamic alterations such as elevated shear stress or increased intravascular pressure, may eventually become maladaptive, leading to impaired vascular function. The vascular endothelium, owing to its location lining the lumen of blood vessels, plays a pivotal role in regulation of all aspects of vascular function and homeostasis.5 Thus, not surprisingly, endothelial dysfunction has been recognized as the harbinger of all major cardiovascular diseases such as hypertension, atherosclerosis, and diabetes.6, 7, 8 The endothelium elaborates a variety of substances that influence vascular tone and protect the vessel wall against inflammatory cell adhesion, thrombus formation, and vascular cell proliferation.8, 9, 10 Among the primary biologic mediators emanating from the endothelium is nitric oxide (NO) and the arachidonic acid metabolite prostacyclin [prostaglandin I2 (PGI2)], which exert powerful vasodilatory, antiadhesive, and antiproliferative effects in the vessel wall
Interventions for improving understanding and minimising the psychological impact of screening
This is the protocol for a review and there is no abstract. The objectives are as follows: The original broad objectives of this review were to identify and assess the effects of interventions that: a) aim to improve people's understanding of screening and the results of the screening process; and b) aim to minimise the adverse psychological impact and/or anxiety associated with screening