437 research outputs found
A Multilepton signal for supersymmetric particles in Tevatron data?
The CDF and D0 collaborations have both reported unusual events in the
dilepton+jets sample with very high lepton and missing transverse energies. It
is possible, but very unlikely, that these events originate from top quark pair
production; however, they have characteristics that are better accounted for by
decays of supersymmetric quarks with mass in the region of 300 GeV: , ,
. Such a supersymmetric
origin also leads to events with large transverse missing energy and either 0,
1, 2 same-sign, or 3 isolated leptons.Comment: 11 pages, 1 figure include
Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions.
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: The nuclear receptors (NRs) are an important class of transcription factors that are conserved across animal phyla. Canonical NRs consist of a DNA-binding domain (DBD) and ligand-binding domain (LBD). While most animals have 20-40 NRs, nematodes of the genus Caenorhabditis have experienced a spectacular proliferation and divergence of NR genes. The LBDs of evolutionarily-conserved Caenorhabditis NRs have diverged sharply from their Drosophila and vertebrate orthologs, while the DBDs have been strongly conserved. The NR2E family of NRs play critical roles in development, especially in the nervous system. In this study, we explore the phylogenetics and function of the NR2E family of Caenorhabditis elegans, using an in vivo assay to test LBD function. RESULTS: Phylogenetic analysis reveals that the NR2E family of NRs consists of three broadly-conserved clades of orthologous NRs. In C. elegans, these clades are defined by nhr-67, fax-1 and nhr-239. The vertebrate orthologs of nhr-67 and fax-1 are Tlx and PNR, respectively. While the nhr-239 clade includes orthologs in insects (Hr83), an echinoderm, and a hemichordate, the gene appears to have been lost from vertebrate lineages. The C. elegans and C. briggsae nhr-239 genes have an apparently-truncated and highly-diverged LBD region. An additional C. elegans NR2E gene, nhr-111, appears to be a recently-evolved paralog of fax-1; it is present in C. elegans, but not C. briggsae or other animals with completely-sequenced genomes. Analysis of the relatively unstudied nhr-111 and nhr-239 genes demonstrates that they are both expressed--nhr-111 very broadly and nhr-239 in a small subset of neurons. Analysis of the FAX-1 LBD in an in vivo assay revealed that it is not required for at least some developmental functions. CONCLUSIONS: Our analysis supports three conserved clades of NR2E receptors, only two of which are represented in vertebrates, indicating three ancestral NR2E genes in the urbilateria. The lack of a requirement for a FAX-1 LBD suggests that the relatively high level of sequence divergence for Caenorhabditis LBDs reflects relaxed selection on the primary sequence as opposed to divergent positive selection. This observation is consistent with a model in which divergence of some Caenorhabditis LBDs is allowed, at least in part, by the absence of a ligand requirement
Editorial: The Human Genome Project
This is the publisher's version, also available electronically from www.jstor.org.No abstract is available for this item
Bigger, Better, Faster, More at the LHC
Multijet plus missing energy searches provide universal coverage for theories
that have new colored particles that decay into a dark matter candidate and
jets. These signals appear at the LHC further out on the missing energy tail
than two-to-two scattering indicates. The simplicity of the searches at the LHC
contrasts sharply with the Tevatron where more elaborate searches are necessary
to separate signal from background. The searches presented in this article
effectively distinguish signal from background for any theory where the LSP is
a daughter or granddaughter of the pair-produced colored parent particle
without ever having to consider missing energies less than 400 GeV.Comment: 26 pages, 8 Figures. Minor textual changes, typos fixed and
references adde
Metastable Vacua in Flux Compactifications and Their Phenomenology
In the context of flux compactifications, metastable vacua with a small
positive cosmological constant are obtained by combining a sector where
supersymmetry is broken dynamically with the sector responsible for moduli
stabilization, which is known as the F-uplifting. We analyze this procedure in
a model-independent way and study phenomenological properties of the resulting
vacua.Comment: 21 pages, 19 figures; v2: matches version published in JHE
High-resolution pulsed field ionization photoelectron–photoion coincidence study of CH4: Accurate 0 K dissociation threshold for CH3+
No abstract prepared
High-resolution pulsed field ionization photoelectron-photoion coincidence spectroscopy using synchrotron radiation
No abstract prepared
Resummation of Yukawa enhanced and subleading Sudakov logarithms in longitudinal gauge boson and Higgs production
Future colliders will probe the electroweak theory at energies much larger
than the gauge boson masses. Large double (DL) and single (SL) logarithmic
virtual electroweak Sudakov corrections lead to significant effects for
observable cross sections. Recently, leading and subleading universal
corrections for external fermions and transverse gauge boson lines were
resummed by employing the infrared evolution equation method. The results were
confirmed at the DL level by explicit two loop calculations with the physical
Standard Model (SM) fields. Also for longitudinal degrees of freedom the
approach was utilized for DL-corrections via the Goldstone boson equivalence
theorem. In all cases, the electroweak Sudakov logarithms exponentiate. In this
paper we extend the same approach to both Yukawa enhanced as well as subleading
Sudakov corrections to longitudinal gauge boson and Higgs production. We use
virtual contributions to splitting functions of the appropriate Goldstone
bosons in the high energy regime and find that all universal subleading terms
exponentiate. The approach is verified by employing a non-Abelian version of
Gribov's factorization theorem and by explicit comparison with existing one
loop calculations. As a side result, we obtain also all top-Yukawa enhanced
subleading logarithms for chiral fermion production at high energies to all
orders. In all cases, the size of the subleading contributions at the two loop
level is non-negligible in the context of precision measurements at future
linear colliders.Comment: 32 pages, 7 figures, uses LaTeX2
Spin Dependence of Massive Lepton Pair Production in Proton-Proton Collisions
We calculate the transverse momentum distribution for the production of
massive lepton-pairs in longitudinally polarized proton-proton reactions at
collider energies within the context of perturbative quantum chromodynamics.
For values of the transverse momentum Q_T greater than roughly half the pair
mass Q, Q_T > Q/2, we show that the differential cross section is dominated by
subprocesses initiated by incident gluons, provided that the polarized gluon
density is not too small. Massive lepton-pair differential cross sections
should be a good source of independent constraints on the polarized gluon
density, free from the experimental and theoretical complications of photon
isolation that beset studies of prompt photon production. We provide
predictions for the spin-averaged and spin-dependent differential cross
sections as a function of Q_T at energies relevant for the Relativistic Heavy
Ion Collider (RHIC) at Brookhaven, and we compare these with predictions for
real prompt photon production.Comment: 34 pages, RevTeX including 17 figures in .ps file
- …