Influence mechanisms of mineralocorticoid receptor antagonist (spironolactone) among elderly patients with chronic heartfailure against ischemic disease

It was determined that a significant positive dynamics of TNF-synthesis suppression by 67.0% (p 0.0001) was established in the 4th group of patients taking combined therapy with the blocker of mineralocorticoid receptors with spironolacton

Contributions of spontaneous phase slippage to linear and non-linear conduction near the Peierls transition in thin samples of o-TaS_3

In the Peierls state very thin samples of TaS_3 (cross-section area \sim 10^{-3} mkm^2) are found to demonstrate smearing of the I-V curves near the threshold field. With approaching the Peierls transition temperature, T_P, the smearing evolves into smooth growth of conductance from zero voltage interpreted by us as the contribution of fluctuations to the non--linear conductance. We identify independently the fluctuation contribution to the linear conductance near T_P. Both linear and non-linear contributions depend on temperature with close activation energies \sim (2 - 4) x 10^3 K and apparently reveal the same process. We reject creep of the {\it continuous} charge-density waves (CDWs) as the origin of this effect and show that it is spontaneous phase slippage that results in creep of the CDW. A model is proposed accounting for both the linear and non-linear parts of the fluctuation conduction up to T_P.Comment: 6 pages, 5 Postscript figure, RevTeX, accepted for publication in PR

Use of L-arginine immobilised on activated carbon for pharmacological correction of endothelial disfunction

For the first time a complex of L-arginine sodium salt of sulfate of cellulose acetate on activated carbon. To investigate the processes of sorption-desorption of L-arginine in a model environmen

Discretized rotation has infinitely many periodic orbits

For a fixed k in (-2,2), the discretized rotation on Z^2 is defined by (x,y)->(y,-[x+ky]). We prove that this dynamics has infinitely many periodic orbits.Comment: Revised after referee reports, and added a quantitative statemen

Multiple Superconducting Phases in New Heavy Fermion Superconductor PrOs4Sb12

The superconducting gap structure of recently discovered heavy fermion superconductor PrOs4Sb12 was investigated by using thermal transport measurements in magnetic field rotated relative to the crystal axes. We demonstrate that a novel change in the symmetry of the superconducting gap function occurs deep inside the superconducting state, giving a clear indication of the presence of two distinct superconducting phases with twofold and fourfold symmetries. We infer that the gap functions in both phases have a point node singularity, in contrast to the familiar line node singularity observed in almost all unconventional superconductors.Comment: 4 Pages, 4 Figure

Parametric Generation of Second Sound by First Sound in Superfluid Helium

We report the first experimental observation of parametric generation of second sound (SS) by first sound (FS) in superfluid helium in a narrow temperature range in the vicinity of $T_\lambda$. The temperature dependence of the threshold FS amplitude is found to be in a good quantitative agreement with the theory suggested long time ago and corrected for a finite geometry. Strong amplitude fluctuations and two types of the SS spectra are observed above the bifurcation. The latter effect is quantitatively explained by the discreteness of the wave vector space and the strong temperature dependence of the SS dissipation length.Comment: 4 pages, 4 postscript figures, REVTE

Parametric generation of second sound in superfluid helium: linear stability and nonlinear dynamics

We report the experimental studies of a parametric excitation of a second sound (SS) by a first sound (FS) in a superfluid helium in a resonance cavity. The results on several topics in this system are presented: (i) The linear properties of the instability, namely, the threshold, its temperature and geometrical dependencies, and the spectra of SS just above the onset were measured. They were found to be in a good quantitative agreement with the theory. (ii) It was shown that the mechanism of SS amplitude saturation is due to the nonlinear attenuation of SS via three wave interactions between the SS waves. Strong low frequency amplitude fluctuations of SS above the threshold were observed. The spectra of these fluctuations had a universal shape with exponentially decaying tails. Furthermore, the spectral width grew continuously with the FS amplitude. The role of three and four wave interactions are discussed with respect to the nonlinear SS behavior. The first evidence of Gaussian statistics of the wave amplitudes for the parametrically generated wave ensemble was obtained. (iii) The experiments on simultaneous pumping of the FS and independent SS waves revealed new effects. Below the instability threshold, the SS phase conjugation as a result of three-wave interactions between the FS and SS waves was observed. Above the threshold two new effects were found: a giant amplification of the SS wave intensity and strong resonance oscillations of the SS wave amplitude as a function of the FS amplitude. Qualitative explanations of these effects are suggested.Comment: 73 pages, 23 figures. to appear in Phys. Rev. B, July 1 st (2001

Integrated evaluation of the endothelioprotective activity of an innovative peptide simulating the alpha-helix of B-erythropoethin in L-name-induced nitrogen oxide deficiency at the late gestation period

To study the efficiency of using carbamylated darbepoetin, asialized erythropoietin and an 11-amino acid peptide that simulating the spatial structure of the B-erythropoietin alpha-helix in the correction of L-NAME-induced nitric oxide deficiency in the late gestation perio

Coupling of the lattice and superlattice deformations and hysteresis in thermal expansion for the quasi one-dimensional conductor TaS3_3

An original interferometer-based setup for measurements of length of needle-like samples is developed, and thermal expansion of o-TaS$_3$ crystals is studied. Below the Peierls transition the temperature hysteresis of length $L$ is observed, the width of the hysteresis loop $\delta L/L$ being up to $5 \cdot 10^{-5}$. The behavior of the loop is anomalous: the length changes so that it is in front of its equilibrium value. The hysteresis loop couples with that of conductivity. The sign and the value of the length hysteresis are consistent with the strain dependence of the charge-density waves (CDW) wave vector. With lowering temperature down to 100 K the CDW elastic modulus grows achieving a value comparable with the lattice Young modulus. Our results could be helpful in consideration of different systems with intrinsic superstructures.Comment: 4 pages, 3 figures. Phys. Rev. Lett., accepted for publicatio