Las instituciones pedagógicas en la comunidad europea

El perfil de los Estados Unidos de Europa va acusándose ya con un cierto relieve. Desde algún tiempo a esta parte, pero sobre todo desde hace un lustro, la prensa diaria ofrece al lector noticia acerca de las actividades de organismos como el Consejo de Europa, Asamblea y Tribunal de Justicia, Comisiones Económica y Atómica, la Comunidad Europeo del Carbón y del Acero, Mercado Conjunto, Euratom; o bien nos informa de los debates mantenidos en el seno del Comité de Acción pro Estados Unidos de Europa sobre la creación de un "distrito europeo" que fuera la sede de todas estas instituciones

Enhanced nonlinear magnetic resonance signals via square wave dipolar fields

This report introduces a new approach that enhances nonlinear solution magnetic resonance signals from intermolecular dipolar interactions. The resulting signals can theoretically be as large as the full equilibrium magnetization. Simple, readily implemented pulse sequences using square-wave magnetization modulation simultaneously refocus all even order intermolecular multiple quantum coherences, leading to a substantial net signal enhancement, complex nonlinear dynamics, and improved structural sensitivity under realistic conditions

Have historical land use/land cover changes triggered a fire regime shift in central Spain?

Fire is one of the main disturbance factors shaping the landscape, and landscape is a key driver of fire behavior. Considering the role played by land use and land cover (LULC) changes as the main driver of landscape dynamics, the aim of this study was to calculate and analyze (i) the real impact of fire on LULC changes and (ii) how these LULC changes were influencing the fire regime. We used methods of historical geography and socio-spatial systemic analysis for reconstructing and assessing the LULC change and fire history in six case studies in the Central Mountain System (Spain) from archival documentary sources and historical cartography. The main result is an accurate dataset of fire records from 1497 to 2013 and a set of LULC maps for three time points (1890s–1930s, 1956–1957, and the 2000s). We have shown the nonlinear evolution of the fire regime and the importance of the local scale when assessing the interaction of landscape dynamics and fire regime variation. Our findings suggest that LULC trends have been the main influencing factor of fire regime variation in Central Spain since the mid-19th centuryinfo:eu-repo/semantics/publishedVersio

Accurate temperature imaging based on intermolecular coherences in magnetic resonance

Conventional magnetic resonance methods that provide interior temperature profiles, which find use in clinical applications such as hyperthermic therapy, can develop inaccuracies caused by the inherently inhomogeneous magnetic field within tissues or by probe dynamics, and work poorly in important applications such as fatty tissues. We present a magnetic resonance method that is suitable for imaging temperature in a wide range of environments. It uses the inherently sharp resonances of intermolecular zero-quantum coherences, in this case flipping up a water spin while flipping down a nearby fat spin. We show that this method can rapidly and accurately assign temperatures in vivo on an absolute scale

High quality optically active and integrable EuOOH films prepared by pulsed laser deposition

Rare-earth (RE)-Oxygen-Hydrogen compounds are versatile materials whose composition and properties can be significantly varied by changing the relative O and H contents. Among them hydrides and oxyhydrides have been thoroughly investigated due to its photochromic properties. Instead, research of RE-hydroxides and oxyhydroxides (RE-OH and RE-OOH) is scarce although they show promising properties as light emitters. However, their use and integration in solid state devices have been hindered so far because their usual chemical synthesis routes yield materials in bulk or powder configurations. In this work we demonstrate a physical deposition route based on pulsed laser deposition that results in the unprecedented preparation of high-quality Eu oxyhydroxide (EuOOH) thin films. The synthetized EuOOH films show a well-defined monoclinic structure, are optically active and show a robust red emission related to the intra-f transitions of the Eu3+ ions. The excellent quality of these crystalline films has allowed us to obtain relevant properties of the monoclinic EuOOH phase not previously reported such as its refractive index and its Raman spectrum, including the identification of the characteristic phonon modes. These novel EuOOH films have been prepared both on Si and fused silica substrates, and thus are ready for potential integration in solid state optoelectronic components and devicesThis work was funded by the Spanish Research Agency (AEI, Ministry of Research and Innovation) and the European Regional Development Fund (ERDF) under grants RTI2018-096498-B-I00, RTI2018-101020-B-I00, RTI2018-096918-B-C41 and PID2021-123190OB-I00; by the CSIC (PIE-202050E195 and project 2021AEP128IO); by the Regional Government of Madrid through TECHNOFUSION(III)CM ´ (S2018/EMT-4437); and by Comunidad de Madrid (Spain) multiannual agreement with UC3M, “Excelencia para el Profesorado Universitario” (EPUC3M14) - Fifth regional research plan 2016-2020. The work of A. Cano was partially supported by the Autonomous Community of Madrid and the European Social Fund (PEJD-2019-PRE/TIC-16082

Headache during pregnancy : an observational study

Introducción: Las cefaleas primarias (CP) tienen mayor prevalencia e incidencia a menor edad y en su mayoría afectan a mujeres. La predilección femenina puede ser explicada por la relación de la cefalea y las hormonas sexuales, en particular el estrógeno. La migraña es la CP más discapacitante. Diversos estudios demuestran que dicha cefalea mejora durante el embarazo, principalmente en cuanto a frecuencia e intensidad. Objetivo: Caracterizar las CP según su intensidad y frecuencia durante el embarazo, además de valorar aspectos demográficos y clínicos asociados en estas pacientes. Materiales y métodos: Estudio descriptivo, transversal que analizó al azar mujeres durante el embarazo o puerperio mediato y se investigó el padecimiento de cefalea antes o durante el curso de dicho estado, mediante un cuestionario realizado por médicos del Servicio de Neurología. Se emplearon criterios de la International Headache Society 2018 (IHS) para la clasificación de cefaleas. Se analizaron datos con EpiInfo 7. Resultados: Se incluyeron 102 pacientes obstétricas. La media de edad fue de 27,6 años (DS+/-7). El 47,1% cursaba puerperio, 40,2% tercer trimestre, 7,8% segundo trimestre, 4,9% primer trimestre. El 14% presentaba antecedentes patológicos previos. El 89,2% padecía CP previa al embarazo siendo mayor en frecuencia la cefalea tensional episódica (61,8%). Se observó que hubo mejoría durante el embarazo en el 71,4%.Además se vio que el 12,8% de las pacientes presentaron cefalea nueva durante el embarazo siendo más frecuente la secundaria (8,8%). Conclusión: Entre las pacientes que presentaban CP previa al embarazo se observó que la mayoría mejoró durante el mismo. Además se concluyó que ante la aparición de cefalea nueva durante el embarazo se deberían realizar estudios complementarios ya que la mayoría fue secundaria a patologías graves.Introduction: Primary headache disorders (PH) are pathologies with high prevalence and incidence in young people, affecting women predominantly. Female predilection is associated with the linkage between headache and sexual hormones, mainly estrogens. Migraine is the most disabling primary headache. Some studies have shown that intensity and frequency of migraine tend to improve during pregnancy. Objetive: Describe primary headaches during pregnancy, in terms of frequency and intensity, and assess demographic and clinical manifestations associated with this condition. Subjects and methods: Descriptive, transversal study that randomly analyzed women during pregnancy or mediate puerperium. Existence of headache before and after these conditions was investigated trough a questionary made by physicians of the Neurology Service. International Headache Society 2018 criteria (IHS) were used to classify headaches. Data were analyzed with EpiInfo 7. Results: One hundred and twoobstetric patients were included. Median agewas 27,6 (SD +/-7). 47,1% patientswere in puerperium, 40,2% in the third trimester, 7.8% in the second trimester and 4.9% in the first trimester. Previous medical history was reported in 14% cases. PH prior to pregnancy was reported in 89.2% patients, being episodic tension headache the most frequent (61.8%). Improvement of headache during pregnancy was detected in 71.4% of the cases. There was a 12,8% of new-onset headache during pregnancy, with the secondary etiology as the most frequent cause (8,8%). Conclusion: Most of the headaches previous to pregnancy improve during this condition. New-onset headache during pregnancy must induce to request complementary studies in order to rule out severe secondary etiologies.Fil: Peñalver, F.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Galiana, G.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Delfino, C.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Farfan Alé, F.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Sánchez, C.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Gonzalez, M.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Giner, F.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Rodríguez, N.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Martínez, M.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y NeurocirugíaFil: Ianardi, S.. Hospital Luis Lagomaggiore (Mendoza, Argentina). Servicio de Neurología y Neurocirugí

Enfermedad de Creutzfeld Jakob, desafío diagnóstico : reporte de dos casos en la ciudad de Mendoza

La enfermedad de Creutzfeldt-Jakob (ECJ) es una afección neurodege-nerativa rápidamente progresiva y mortal producida por priones. Es la más común de las encefalopatías espongiformes. La hipótesis prevalente sugiere que se inicia y propaga por conversión de una proteína priónica normal (PrP) en una isoforma conformacional anormal (PrPreS), que se acumula en el cerebro causando destrucción neuronal. Se reporta el caso de dos pacientes asistido en el Servicio de Neurología del Hospital Lagomaggiore de la ciudad de Mendoza en el período de 2 años: mujer de 49 años con cuadro de deterioro cognitivo rápidamente progresivo asociado a trastorno de la marcha y ataxia de 2 meses de evolución; y varón de 54 años con conductas inapropiadas y desorientación temporo-espacial de 20 días de evolución. Ambos con EEG compatible y proteína 14.3.3 positiva, falleciendo semanas después del diagnóstico. Se discute ambos casos, los cuales representaron un desafío diagnóstico dada la baja frecuencia y escaso reconocimiento de esta entidad en nuestro medio, debiendo debe ser considerado en pacientes que evolucionan a una demencia rápidamente progresiva.Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and fatal neurodegenerative disease caused by prions. It is the most common of spongiform encephalopathies. The most accepted hypothesis suggests that it initiates and propagates through conversion of normal prion protein (PrP) in an abnormal conformational isoform (PrPres), which accumulates in the brain causing neuronal destruction. The cases of two patients assisted in the Department of Neurology of Hospital Lagomaggiore city of Mendoza in 2-year period are reported: A 49-year old female patient with symptoms of rapidly progressing cognitive impairment associated with gait disturbance and ataxia of 2 months of progression; and a 54-year old male with misconduct and temporo-spatial disorientation of 20 days of evolution. In both cases, EEG was compatible with CJD and 14.3.3 protein was positive, dying weeks after diagnosis. Both cases are discussed, which represented a diagnostic challenge given the low frequency and little recognition of this entity in our environment, must be considered in patients who develop a rapidly progressive dementia.Fil: Galiana, Graciana Lourdes. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Farfan Alé, F.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: De Monte, M.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Sánchez, C.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Torres, A.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Ianardi, S.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Genco, J.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Genco, D.. Hospital Luis Lagomaggiore (Mendoza, Argentina)Fil: Castellino, G.. Hospital Luis Lagomaggiore (Mendoza, Argentina