Attendance of MSM at Genitourinary Medicine services in England: implications for selective HPV vaccination programme (a short communication)

Background Human papillomaviruses (HPV) immunisation programmes for female adolescents in the UK offer relatively little benefit to men who have sex with men (MSM). Targeted HPV vaccination for MSM may reduce the high incidence of HPV-related disease among MSM. We used national data from sexual health clinics to calculate the number of MSM attending these clinics throughout England from 2009 to 2014 and to identify their characteristics, to inform the implementation of a targeted HPV vaccination programme in MSM. Methods We used the Genitourinary Medicine Clinic Activity Dataset (GUMCADv2) to obtain data for men aged 15–70 years who had attended a GUM clinic in England from 2009 to 2014. We analysed both numbers of MSM attending and number of GUM attendances, age at first attendance, ethnicity and geographical area of the clinic in England. Results A total of 374 983 MSM attended sexual health services in England between 2009 and 2014. Median age of presentation was 32 years (IQR 25–41) and showed regional geographical variation. Of all men attending sexual health clinics in England, the highest proportion of those identifying as MSM was in London (21%). Excluding visits within 1 month of an initial attendance, 49% of all MSM re-attended within 12 months and 58% within 24 months. MSM aged ≥36 years reattended more frequently than younger MSM. 51% reattended at least twice within 24 months of initial visit. Conclusions The majority of MSM reattend clinic at least once within a 24-month period, potentially facilitating the delivery of a three-dose HPV vaccination programme. This would reduce the burden on sexual health clinics and cost to local authorities due to extra visits if HPV vaccination were to be delivered through these services

Fast scan control for deflection type mass spectrometers

A high speed scan device is reported that allows most any scanning sector mass spectrometer to measure preselected gases at a very high sampling rate. The device generates a rapidly changing staircase output which is applied to the accelerator of the spectrometer and it also generates defocusing pulses that are applied to one of the deflecting plates of the spectrometer which when shorted to ground deflects the ion beam away from the collector. A defocusing pulse occurs each time there is a change in the staircase output

Photometric Metallicities in Bootes I

We present new Stromgren and Washington data sets for the Bootes I dwarf galaxy, and combine them with the available SDSS photometry. The goal of this project is to refine a ground-based, practical, accurate method to determine age and metallicity for individual stars in Bootes I that can be selected in an unbiased imaging survey, without having to take spectra. We produce photometric metallicities from Stromgren and Washington photometry, for stellar systems with a range of $-1.0>[Fe/H]>-3.5$. To avoid the decrease in sensitivity of the Stromgren metallicity index on the lower red-giant branch, we replace the Stromgren v-filter with the broader Washington C-filter; we find that $CT_1by$ is the most successful filter combination, for individual stars with $[Fe/H]<-2.0$, to maintain ~0.2 dex $[Fe/H]$-resolution over the whole red-giant branch. We demonstrate that we can break the isochrones' age-metallicity degeneracy with these filters, using stars with log g=2.5-3.0, which have less than a 2% change in their $(C-T_1)$-colour due to age, over a range of 11-14 Gyr.Comment: 24 pages, 18 figures, accepted by MNRA

Peer-to-peer:is deviant behavior the norm on P2P file-sharing networks?

P2P file-sharing networks such as Kazaa, eDonkey, and Limewire boast millions of users. Because of scalability concerns and legal issues, such networks are moving away from the semicentralized approach that Napster typifies toward more scalable and anonymous decentralized P2P architectures. Because they lack any central authority, these networks provide a new, interesting context for the expression of human social behavior. However, the activities of P2P community members are sometimes at odds with what real-world authorities consider acceptable. One example is the use of P2P networks to distribute illegal pornography. To gauge the form and extent of P2P-based sharing of illegal pornography, we analyzed pornography-related resource-discovery traffic in the Gnutella P2P network. We found that a small yet significant proportion of Gnutella activity relates to illegal pornography: for example, 1.6 percent of searches and 2.4 percent of responses are for this type of material. But does this imply that such activity is widespread in the file-sharing population? On the contrary, our results show that a small yet particularly active subcommunity of users searches for and distributes illegal pornography, but it isn't a behavioral norm

Determination of water content using mass spectrometry

Mass spectrometer is used to measure small quantities of water present in different materials. System has been applied in measuring water and gases desorbed from microcircuitry insulation, can also be used with foods, polymeric materials, and organic solvents

Dynamic delta method for trace gas analysis

Method has been developed in which measurements are made only over viscous flow range, eliminating fractionation before the molecular leak and problems due to surface elution

Determining the venting efficiency of simple chimneys for buoyant plumes

We present preliminary results from an examination of the capture and venting of a buoyant plume by a chimney. The aim is to enable improved management of indoor pollutant sources – for instance, the plume rising from a cooking pan in a kitchen or a cooking fire in a hut. Using the principle of dynamic similarity, we precise ly and controllably model the behaviour of indoor plumes by using saline solutions ejected into an enclosure containing freshwater. These well - established laboratory analogue techniques enable the location and concentration of tracer in the plume to be eas ily tracked, reflecting the evolution of pollutants carried in the plume. Focusing on a plume within a room containing a quiescent ambient environment, we identify two physical mechanisms potentially responsible for driving the removal of pollutants. The f irst, we describe as the capture of the plume, a process driven by the direct interaction between the plume and the evacuation opening; the second, we describe as the draining flow driven by a buoyant layer of fluid which may accumulate at the ceiling and is then evacuated through the effects of buoyancy. We first demonstrate that the addition of a simple cylindrical chimney that hangs downwards from an opening in the (analogue) ceiling increases the venting efficiency of these potentially polluting plumes. We go on to examine how the capture efficiency of these simple chimneys varies as the relative size of the plume and the chimney are altered, and demonstrate that simple model can provide predictions of the observed variation in capture efficiency

Double-impulse magnetic focusing of launched cold atoms.

We have theoretically investigated three-dimensional focusing of a launched cloud of cold atoms using a pair of magnetic lens pulses (the alternate-gradient method). Individual lenses focus radially and defocus axially or vice versa. The performance of the two possible pulse sequences are compared and found to be ideal for loading both 'pancake' and 'sausage' shaped magnetic/optical microtraps. It is shown that focusing aberrations are considerably smaller for double-impulse magnetic lenses compared to single-impulse magnetic lenses. An analysis of clouds focused by the double-impulse technique is presented

Continuous-Time Random Walks at All Times

Continuous-time random walks (CTRW) play important role in understanding of a wide range of phenomena. However, most theoretical studies of these models concentrate only on stationary-state dynamics. We present a new theoretical approach, based on generalized master equations picture, that allowed us to obtain explicit expressions for Laplace transforms for all dynamic quantities for different CTRW models. This theoretical method leads to the effective description of CTRW at all times. Specific calculations are performed for homogeneous, periodic models and for CTRW with irreversible detachments. The approach to stationary states for CTRW is analyzed. Our results are also used to analyze generalized fluctuations theorem

Nonlinear photon transport in a semiconductor waveguide-cavity system containing a single quantum dot: Anharmonic cavity-QED regime

We present a semiconductor master equation technique to study the input/output characteristics of coherent photon transport in a semiconductor waveguide-cavity system containing a single quantum dot. We use this approach to investigate the effects of photon propagation and anharmonic cavity-QED for various dot-cavity interaction strengths, including weakly-coupled, intermediately-coupled, and strongly-coupled regimes. We demonstrate that for mean photon numbers much less than 0.1, the commonly adopted weak excitation (single quantum) approximation breaks down, even in the weak coupling regime. As a measure of the anharmonic multiphoton-correlations, we compute the Fano factor and the correlation error associated with making a semiclassical approximation. We also explore the role of electron--acoustic-phonon scattering and find that phonon-mediated scattering plays a qualitatively important role on the light propagation characteristics. As an application of the theory, we simulate a conditional phase gate at a phonon bath temperature of $20$K in the strong coupling regime.Comment: To appear in PR