TRACKING OF MOVING OBJECT IN WIRELESS SENSOR NETWORK

A Wireless Sensor Network is a collection of sensor nodes distributed into a network to monitor the environmental conditions and send the sensed data to the Base Station. Wireless Sensor Network is one of the rapidly developing area in which energy consumption is the most important aspect to be considered while tracking, monitoring, reporting and visualization of data. An Energy Efficient Prediction-based Clustering algorithm is proposed to track the moving object in wireless sensor network. This algorithm reduces the number of hops between transmitter and receiver nodes and also the number of transmitted packets. In this method, the sensor nodes are statically placed and clustered using LEACH-R algorithm. The Prediction based clustering algorithm is applied where few nodes are selected for tracking which uses the prediction mechanism to predict the next location of the moving object. The Current Location of the target is found using Trilateration algorithm. The Current Location or Predicted Location is sent to active Cluster Head from the leader node or the other node. Based on which node send the message to the Cluster Head, the Predicted or Current Location will be sent to the base station. In real time, the proposed work is applicable in traffic tracking and vehicle tracking. The experiment is carried out using Network Stimulator-2 environment. Simulation result shows that the proposed algorithm gives a better performance and reduces the energy consumption

Optimizing differential identifiability improves connectome predictive modeling of cognitive deficits from functional connectivity in Alzheimer's disease

Functional connectivity, as estimated using resting state functional MRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of individual functional connectomes and lack of generalizability of models predicting cognitive outcomes from connectivity. To address these issues, we combine the frameworks of connectome predictive modeling and differential identifiability. Using the combined framework, we show that enhancing the individual fingerprint of resting state functional connectomes leads to robust identification of functional networks associated to cognitive outcomes and also improves prediction of cognitive outcomes from functional connectomes. Using a comprehensive spectrum of cognitive outcomes associated to Alzheimer's disease (AD), we identify and characterize functional networks associated to specific cognitive deficits exhibited in AD. This combined framework is an important step in making individual level predictions of cognition from resting state functional connectomes and in understanding the relationship between cognition and connectivity

Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair

Shape variation of human head hair shows striking variation within and between human populations, while its genetic basis is far from being understood. We performed a series of genome-wide association studies (GWASs) and replication studies in a total of 28 964 subjects from 9 cohorts from multiple geographic origins. A meta-analysis of three European GWASs identified 8 novel loci (1p36.23

Analysis of phytochemical constituents and antibacterial activity of Wrightia tinctoria: traditional medicinal plant of India for application on wound dressing materials

Wrightia tinctoria is one of the important traditional medicinal plants used in the treatment of various diseases. The idea of the research is to study the presence of phytochemicals and test the antibacterial activity of Wrightia tinctoria leaf extracts on nonwoven fabrics to find its suitability for wound dressings. The methodology includes identification and collection of W.tinctoria leaves, preparation of leaf powder, determination of physicochemical analysis, extraction using different solvents, preliminary phytochemical screening, quantitative estimation of phytoconstituents, yield of the extracts and determination of antibacterial activity on treated fabrics. Results revealed the presence of more active metabolites in the extracts of W.tinctoria which may be the reason for the promising antibacterial potential against the bacterial strains. As a promising ethnomedicinal plant, Wrightia tinctoria may serve as a major source of useful drugs finding its suitability for developing wound dressings

Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair

Shape variation of human head hair shows striking variation within and between human populations, while its genetic basis is far from being understood. We performed a series of genome-wide association studies (GWASs) and replication studies in a total of 28 964 subjects from 9 cohorts from multiple geographic origins. A meta-analysis of three European GWASs identified 8 novel loci (1p36.23 ERRFI1/SLC45A1, 1p36.22 PEX14, 1p36.13 PADI3, 2p13.3 TGFA, 11p14.1 LGR4, 12q13.13 HOXC13, 17q21.2 KRTAP, and 20q13.33 PTK6), and confirmed 4 previously known ones (1q21.3 TCHH/TCHHL1/LCE3E, 2q35 WNT10A, 4q21.21 FRAS1, and 10p14 LINC00708/GATA3), all showing genome-wide significant association with hair shape (