Mixed-method tutoring support improves learning outcomes of veterinary students in basic subjects

P. 1-10Tutoring is a useful tool in the university teaching-learning binomial, although its development is impaired in large classes. Recent improvements in information and communication technologies have made tutoring possible via the Internet. The aim of this study was to evaluate the efficacy of mixed-method academic tutoring in two basic subjects in Veterinary Science studies at the University of León (Spain) to optimize the usefulness of tutoring support in the college environment. This quasi-experimental study was firstly carried out as a pilot study in a small group of tutored students of “Cytology and Histology” (CH) (47/186; 25.3%) and “Veterinary Pharmacology” (VP) (33/141; 23.4%) subjects, and was implemented in a large class of CH the next academic year (150 students) while comparing the results with those obtained in a previous tutorless course (162 students). Tutored students were given access to online questionnaires with electronic feedback on each subject. In addition to traditional tutoring carried out in both tutored and tutorless students, the pilot study included three sessions of face-to-face tutoring in order to monitor the progress of students. Its efficacy was assessed by monitoring students’ examination scores and attendance as well as a satisfaction survey. Online tutoring support, together with conventional teaching methods, may be a useful method to incorporate student-centered learning in basic subjects in Veterinary Science.S

Arqueología del genocidio en Tucumán: Biografías, inhumaciones, espacios concentracionarios y cartografías

Los trabajos forenses realizados por el Colectivo de Arqueología, Memoria e Identidad de Tucumán (CAMIT), en el marco de causas judiciales, posibilitaron tanto recuperar e identificar nominalmente a 113 personas en el denominado “Pozo de Vargas” como así también contribuir con pruebas referidas a la dinámica del Centro de Exterminio que funcionó en el predio militar Compañía de Arsenales Miguel de Azcuénaga. Estas investigaciones pusieron en manifiesto las estrechas relaciones entre una diversidad de lugares que fueron integrados a la política de exterminio diseñada por las fuerzas de seguridad y armadas durante el período comprendido entre los años 1975 y 1983. En efecto, no es posible dimensionar las características que asumió el genocidio a escala provincial si no se vinculan materialidades y testimonios y que viabilizan -conjuntamente- dar cuenta de la complejidad de la persecución, represión y exterminio de una importante fracción social. Durante los últimos años desde el equipo nos abocamos a determinar las biografías de cada uno/a de los/las hombres y mujeres recuperados/as en el Pozo de Vargas, para ello centramos la atención en: la información disponible en cada caso (ampliándola con nuevas indagaciones –entrevistas, relevamiento en distintos archivos, etc.–, reevaluación de la información disponible, etc.); definir grupos hacia el interior del universo de identificados hasta el momento en dicha inhumación clandestina (los grupos fueron delimitados considerando distintas variables tales como: militancias sociales y políticas; trabajo y ocupación; etc.); y, evaluando la información disponible sobre los lugares donde atravesaron sus experiencias concentracionarias (en Tucumán y en otras provincias). Como resultado preliminar –en esta primera etapa del trabajo prestamos mayor atención a la capital tucumana y al período comprendido entre 1975 y 1978- contamos actualmente con mayor información referida a las trayectorias de las personas: desde sus secuestros -y los distintos espacios de reclusión clandestinos por los que transitaron- hasta sus asesinatos y ocultamiento de los cuerpos en el Pozo de Vargas. Asimismo, tales itinerarios fueron incorporados a cartografías personales y colectivas que posibilitan evaluar, por ejemplo, aquellos aspectos de logística y diseño de circuitos a los fines de efectivizar el exterminio. Tales cartografías, además, destacan una diversidad de espacios –entre privados y públicos– involucrados a los fines de llevar a cabo una matanza como la perpetrada en la provincia de Tucumán. Toda esta información posibilita dimensionar las características que asumió el genocidio a una escala local.Fil: Ataliva, Víctor Hugo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Estudios Sociales. Universidad Nacional de Tucumán. Instituto Superior de Estudios Sociales; Argentina. Colectivo de Arqueología Memoria E Identidad de Tucumán; ArgentinaFil: Gerónimo, A.. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Huetagoyena Gutiérrez, G.. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Zurita, R. D.. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Cano, S.. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo. Instituto Interdisciplinario de Estudios Andinos; Argentina. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Molina, L. R.. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Romano, Andres Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Estudios Sociales. Universidad Nacional de Tucumán. Instituto Superior de Estudios Sociales; Argentina. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Srur, Florencia Rocío. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Lund, Julia. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo. Instituto de Arqueología y Museo; Argentina. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaFil: Leiva, A.. Colectivo de Arqueología, Memoria e Identidad de Tucumán; ArgentinaXIV Jornadas Internas de Comunicaciones en Investigación, Docencia y ExtensiónSan Miguel de TucumánArgentinaUniversidad Nacional de Tucumán. Facultad de Ciencias Naturales. Instituto Miguel Lill

The QUIJOTE experiment: project overview and first results

QUIJOTE (Q-U-I JOint TEnerife) is a new polarimeter aimed to characterize the polarization of the Cosmic Microwave Background and other Galactic and extragalactic signals at medium and large angular scales in the frequency range 10-40 GHz. The multi-frequency (10-20~GHz) instrument, mounted on the first QUIJOTE telescope, saw first light on November 2012 from the Teide Observatory (2400~m a.s.l). During 2014 the second telescope has been installed at this observatory. A second instrument at 30~GHz will be ready for commissioning at this telescope during summer 2015, and a third additional instrument at 40~GHz is now being developed. These instruments will have nominal sensitivities to detect the B-mode polarization due to the primordial gravitational-wave component if the tensor-to-scalar ratio is larger than r=0.05.Comment: To appear in "Highlights of Spanish Astrophysics VIII", Proceedings of the XI Scientific Meeting of the Spanish Astronomical Society, Teruel, Spain (2014

Infrastructures and Installation of the Compact Muon Solenoid Data Acquisition at CERN

At the time of this paper, all hardware elements of the CMS Data Acquisition System have been installed and commissioned both in the underground and surface areas. This paper describes in detail the infrastructures and the different steps that were necessary from the very beginning when the underground control rooms and surface building were building sites to a working system collecting data fragment from ~650 sources and sending them to surface for assembly and analysis

Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer:A Population-Based Case-Control Study and Meta-Analysis

In this study, we have evaluated whether 57 genome-wide association studies (GWAS)-identified common variants for type 2 diabetes (T2D) influence the risk of developing prostate cancer (PCa) in a population of 304 Caucasian PCa patients and 686 controls. The association of selected single nucleotide polymorphisms (SNPs) with the risk of PCa was validated through meta-analysis of our data with those from the UKBiobank and FinnGen cohorts, but also previously published genetic studies. We also evaluated whether T2D SNPs associated with PCa risk could influence host immune responses by analysing their correlation with absolute numbers of 91 blood-derived cell populations and circulating levels of 103 immunological proteins and 7 steroid hormones. We also investigated the correlation of the most interesting SNPs with cytokine levels after in vitro stimulation of whole blood, peripheral mononuclear cells (PBMCs), and monocyte-derived macrophages with LPS, PHA, Pam3Cys, and Staphylococcus Aureus. The meta-analysis of our data with those from six large cohorts confirmed that each copy of the FTOrs9939609A, HNF1Brs7501939T, HNF1Brs757210T, HNF1Brs4430796G, and JAZF1rs10486567A alleles significantly decreased risk of developing PCa (p = 3.70 × 10−5, p = 9.39 × 10−54, p = 5.04 × 10−54, p = 1.19 × 10−71, and p = 1.66 × 10−18, respectively). Although it was not statistically significant after correction for multiple testing, we also found that the NOTCH2rs10923931T and RBMS1rs7593730 SNPs associated with the risk of developing PCa (p = 8.49 × 10−4 and 0.004). Interestingly, we found that the protective effect attributed to the HFN1B locus could be mediated by the SULT1A1 protein (p = 0.00030), an arylsulfotransferase that catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic com-pounds. In addition to these results, eQTL analysis revealed that the HNF1Brs7501939, HNF1Brs757210, HNF1Brs4430796, NOTCH2rs10923931, and RBMS1rs7593730 SNPs influence the risk of PCa through the modulation of mRNA levels of their respective genes in whole blood and/or liver. These results confirm that functional TD2-related variants influence the risk of developing PCa, but also highlight the need of additional experiments to validate our functional results in a tumoral tissue context

The CMS High Level Trigger System

The CMS Data Acquisition (DAQ) System relies on a purely software driven High Level Trigger (HLT) to reduce the full Level-1 accept rate of 100 kHz to approximately 100 Hz for archiving and later offline analysis. The HLT operates on the full information of events assembled by an event builder collecting detector data from the CMS front-end systems. The HLT software consists of a sequence of reconstruction and filtering modules executed on a farm of O(1000) CPUs built from commodity hardware. This paper presents the architecture of the CMS HLT, which integrates the CMS reconstruction framework in the online environment. The mechanisms to configure, control, and monitor the Filter Farm and the procedures to validate the filtering code within the DAQ environment are described

Validación de la producción masiva de las micorrizas como alternativa agroambiental para los pequeños productores del municipio de Restrepo :informe final

Los problemas generados por el uso de la agricultura intensiva en el Piedemonte Llanero, zona de mayor desarrollo agrícola de los Llanos Orientales, ha propiciado la degradación progresiva del ambiente y la reducción de la productividad de los cultivos, por lo cual surge la necesidad de establecer estrategias viables que aportan beneficios económicos y ambientales como el uso de biofertilizantes donde las micorrizas se convierten en una importante alternativa para los sistemas de producción integrados, acompañados de prácticas sostenibles de manejo agrícola que permitan mejorar la calidad de los agroecosistemas y contribuir al logro de un desarrollo socioeconómico equitativo de los pequeños productores agrícolas del municipio de Restrepo, mediante la validación y apropiación de la tecnología de uso y producción de las micorrizas

Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019

Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population