NUMERICAL SIMULATION OF GAS-SOLID FLOW IN AN INTERCONNECTED FLUIDIZED BED

The gas-particles flow in an interconnected bubbling fluidized cold model is simulated using a commercial CFD package by Ansys. Conservation equations of mass and momentum are solved using the Eulerian granular multiphase model. Bubbles formation and their paths are analyzed to investigate the behaviour of the bed at different gas velocities. Experimental tests, carried out by the cold model, are compared with simulation runs to study the fluidization quality and to estimate the circulation of solid particles in the bed

Production of Gaseous Carriers Via Biomass Gasification for Energy Purposes

AbstractIt is under development a biomass gasification plant based on a 1 MWth bubbling fluidized bed (BFB) reactor with internal recirculation. Compared to conventional BFB design, the mechanism of internal circulation of solids can give beneficial effect to the process in terms of biomass conversion efficiency into gaseous product and gas quality. A model describing the process of biomass gasification in the two reaction chambers was developed. Expected results were preliminarily validated by experimental results obtained at a bench scale facility working on the same gasification concept

Città storiche & turismo nell'Italia Centrale. Il cinema per cercare l'anima delle città e per sostenere nuove politiche urbane

Documenta un seminario organizzato a Corinaldo AN nel settembre 2006 da G.Sergi e da C.Aslan dell'EAPLV Parig

Outcomes of patients with drug-resistant-tuberculosis treated with bedaquiline-containing regimens and undergoing adjunctive surgery

Objectives: No study evaluated the contribution of adjunctive surgery in bedaquiline-treated patients. This study describes treatment outcomes and complications in a cohort of drug-resistant pulmonary tuberculosis (TB) cases treated with bedaquiline-containing regimens undergoing surgery.Methods: This retrospective observational study recruited patients treated for TB in 12 centres in 9 countries between January 2007 and March 2015.Patients who had surgical indications in a bedaquiline-treated programme-based cohort were selected and surgery-related information was collected. Patient characteristics and surgical indications were described together with type of operation, surgical complications, bacteriological conversion rates, and treatment outcomes. Treatment outcomes were evaluated according to the time of surgery.Results: 57 bedaquiline-exposed cases resistant to a median of 7 drugs had indication for surgery (52 retreatments; 50 extensively drug-resistant (XDR) or pre XDR-TB). Sixty percent of cases initiated bedaquiline treatment following surgery, while 36.4% underwent the bedaquiline regimen before surgery and completed it after the operation. At treatment completion 90% culture-converted with 69.1% achieving treatment success; 21.8% had unfavourable outcomes (20.0% treatment failure, 1.8% lost to follow-up), and 9.1% were still undergoing treatment.Conclusions: The study results suggest that bedaquiline and surgery can be safely and effectively combined in selected cases with a specific indication. (C) 2018 The British Infection Association. Published by Elsevier Ltd. All rights reserved

What counts more: The patient, the surgical technique, or the hospital? A multivariable analysis of factors affecting perioperative complications of pulmonary lobectomy by video-assisted thoracoscopic surgery from a large nationwide registry

OBJECTIVES: Inherent technical aspects of pulmonary lobectomy by video-assisted thoracoscopic surgery (VATS) may limit surgeons' ability to deal with factors predisposing to complications. We analysed complication rates after VATS lobectomy in a prospectively maintained nationwide registry. METHODS: The registry was queried for all consecutive VATS lobectomy procedures from 49 Italian Thoracic Units. Baseline condition, tumour features, surgical techniques, devices, postoperative care, complications, conversions and the reasons thereof were detailed. Univariable and multivariable regressions were used to assess factors potentially linked to complications. RESULTS: Four thousand one hundred and ninety-one VATS lobectomies in 4156 patients (2480 men, 1676 women) were analysed. The median age-adjusted Charlson index of the patients was 4 (interquartile range 3-6). Grade 1 and 2 and Grade 3-5 complications were observed in 20.1% and in 5.8%, respectively. Ninety-day mortality was 0.55%. The overall conversion rate was 9.2% and significantly higher in low-volume centres (<100 cases, P < 0.001), but there was no significant difference between intermediate- and high-volume centres under this aspect. Low-volume centres were significantly more likely to convert due to issues with difficult local anatomy, but not significantly so for bleeding. Conversion, lower case-volume, comorbidity burden, male gender, adhesions, blood loss, operative time, sealants and epidural analgesia were significantly associated with increased postoperative morbidity. CONCLUSIONS: VATS lobectomy is a safe procedure even in medically compromised patients. An improved classification system for conversions is proposed and prevention strategies are suggested to reduce conversion rates and possibly complications in less-experienced centres

Corrigendum to: What counts more: The patient, the surgical technique, or the hospital? A multivariable analysis of factors affecting perioperative complications of pulmonary lobectomy by video-assisted thoracoscopic surgery from a large nationwide registry (European Journal of Cardio-thoracic Surgery (2019) DOI: 10.1093/ejcts/ezz187)

reserved88noErratumIn the originally published version of this article the list of the Italian VATS group members is missing. The names of the members have now been included.mixedInfante, M.V.; Benato, C.; Silva, R.; Rocco, G.; Bertani, A.; Bertolaccini, L.; Gonfiotti, A.; Giovannetti, R.; Bonadiman, C.; Lonardoni, A.; Canneto, B.; Falezza, G.; Gandini, P.; Curcio, C.; Crisci, R.; Zaraca, F.; Alloisio, M.; Amore, D., Ampollini, L.; Andreetti, C.; Argnani, D.; Baietto, G.; Bandiera, A.; Benvenuti, M.; Bortolotti, L.; Bottoni, E.; Breda, C.; Camplese, P.; Carbognani, P.; Cardillo, G.; Casadio, C.; Cavallesco, G.; Cherchi, R.; Dell'Amore, A.; Beffa, V.; Dolci, G; Droghetti, A; Ferrari, P.A.; Fontana, D.; Gargiulo, G.; Gasparri, R.; Gavezzoli, D.; Ghisalberti, M.; Giovanardi, M.; Guerrera, F.; Imperatori, A.; Iurilli, L.; Lausi, P.; Lo Giudice, F.; Londero, F.; Lopez, C.; Luzzi, L.; Mancuso, M.; Maniscalco, P.; Margaritora, S.; Meacci, E.; Melloni, G.; Morelli, A.; Mucilli, F.; Natali, P.;, Negri, G.; Nicotra, S.; Nosotti, M.; Pariscenti, G.; Perkmann, R.; Pernazza, F.; Pirondini, E.; Poggi, C.; Puma, F.; Refai, M.; Rinaldo, A.; Rizzardi, G; Rosso, L.; Rotolo, N.; Russo, E.; Sabbatini, A.; Scarci, M.; Spaggiari, L.; Stefani, A.; Solli, P.; Surrente, C.; Terzi, A.; Torre, M.; Vinci, D.; Viti, A.; Voltolini, L.; Zaccagna, G.; the Italian VATS group membersInfante, M. V.; Benato, C.; Silva, R.; Rocco, G.; Bertani, A.; Bertolaccini, L.; Gonfiotti, A.; Giovannetti, R.; Bonadiman, C.; Lonardoni, A.; Canneto, B.; Falezza, G.; Gandini, P.; Curcio, C.; Crisci, R.; Zaraca, F.; Alloisio, M.; Amore, D.; Ampollini, L.; Andreetti, C.; Argnani, D.; Baietto, G.; Bandiera, A.; Benvenuti, M.; Bortolotti, L.; Bottoni, E.; Breda, C.; Camplese, P.; Carbognani, P.; Cardillo, G.; Casadio, C.; Cavallesco, G.; Cherchi, R.; Dell'Amore, A.; Beffa, V.; Dolci, G; Droghetti, A; Ferrari, P. A.; Fontana, D.; Gargiulo, G.; Gasparri, R.; Gavezzoli, D.; Ghisalberti, M.; Giovanardi, M.; Guerrera, F.; Imperatori, A.; Iurilli, L.; Lausi, P.; Lo Giudice, F.; Londero, F.; Lopez, C.; Luzzi, L.; Mancuso, M.; Maniscalco, P.; Margaritora, S.; Meacci, E.; Melloni, G.; Morelli, A.; Mucilli, F.; Natali, P.; Negri, G.; Nicotra, S.; Nosotti, M.; Pariscenti, G.; Perkmann, R.; Pernazza, F.; Pirondini, E.; Poggi, C.; Puma, F.; Refai, M.; Rinaldo, A.; Rizzardi, G; Rosso, L.; Rotolo, N.; Russo, E.; Sabbatini, A.; Scarci, M.; Spaggiari, L.; Stefani, A.; Solli, P.; Surrente, C.; Terzi, A.; Torre, M.; Vinci, D.; Viti, A.; Voltolini, L.; Zaccagna, G.; the Italian VATS group, Member

What counts more: The patient, the surgical technique, or the hospital? A multivariable analysis of factors affecting perioperative complications of pulmonary lobectomy by video-assisted thoracoscopic surgery from a large nationwide registry

Inherent technical aspects of pulmonary lobectomy by video-assisted thoracoscopic surgery (VATS) may limit surgeons' ability to deal with factors predisposing to complications. We analysed complication rates after VATS lobectomy in a prospectively maintained nationwide registry.OBJECTIVES: Inherent technical aspects of pulmonary lobectomy by video-assisted thoracoscopic surgery (VATS) may limit surgeons' ability to deal with factors predisposing to complications. We analysed complication rates after VATS lobectomy in a prospectively maintained nationwide registry.METHODS: The registry was queried for all consecutive VATS lobectomy procedures from 49 Italian Thoracic Units. Baseline condition, tumour features, surgical techniques, devices, postoperative care, complications, conversions and the reasons thereof were detailed. Univariable and multivariable regressions were used to assess factors potentially linked to complications.RESULTS: Four thousand one hundred and ninety-one VATS lobectomies in 4156 patients (2480 men, 1676 women) were analysed. The median age-adjusted Charlson index of the patients was 4 (interquartile range 3-6). Grade 1 and 2 and Grade 3-5 complications were observed in 20.1% and in 5.8%, respectively. Ninety-day mortality was 0.55%. The overall conversion rate was 9.2% and significantly higher in low-volume centres (<100 cases, P < 0.001), but there was no significant difference between intermediate- and high-volume centres under this aspect. Low-volume centres were significantly more likely to convert due to issues with difficult local anatomy, but not significantly so for bleeding. Conversion, lower case-volume, comorbidity burden, male gender, adhesions, blood loss, operative time, sealants and epidural analgesia were significantly associated with increased postoperative morbidity.CONCLUSIONS: VATS lobectomy is a safe procedure even in medically compromised patients. An improved classification system for conversions is proposed and prevention strategies are suggested to reduce conversion rates and possibly complications in less-experienced centres